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VERAPAMIL ER (verapamil HCl)
- Hypertension
- Verelan Capsule,extended Release
- Verapamil Er Tab
- Verapamil Er 24 Hr Capsule,extended Release
- Verapamil Er 24 Hr Cap
- Verapamil Er (sr) Tablet,extended Release
- Calan Sr Tablet,extended Release
- By Indication
120 mg capsule,extended release
- 1 capsule (120 mg) by oral route once daily
180 mg capsule,extended release
- 1 capsule (180 mg) by oral route once daily
240 mg capsule,extended release
- 1 capsule (240 mg) by oral route once daily
360 mg capsule,extended release
- 1 capsule (360 mg) by oral route once daily
ER (SR) 120 mg tablet,extended release
- 1 tablet (120 mg) by oral route once daily with food
ER (SR) 180 mg tablet,extended release
- 1 tablet (180 mg) by oral route once daily with food
ER (SR) 240 mg tablet,extended release
- 1 tablet (240 mg) by oral route once daily with food
120 mg 24 hr capsule,extended release
- 1 capsule (120 mg) by oral route once daily
180 mg 24 hr capsule,extended release
- 1 capsule (180 mg) by oral route once daily
240 mg 24 hr capsule,extended release
- 1 capsule (240 mg) by oral route once daily
360 mg 24 hr capsule,extended release
- 1 capsule (360 mg) by oral route once daily
ER 120 mg 24 hr capsule,extended release
- 1 capsule (120 mg) by oral route once daily
ER 180 mg 24 hr capsule,extended release
- 1 capsule (180 mg) by oral route once daily
ER 240 mg 24 hr capsule,extended release
- 1 capsule (240 mg) by oral route once daily
ER 360 mg 24 hr capsule,extended release
- 1 capsule (360 mg) by oral route once daily
verapamil ER 120 mg 24 hr capsule,extended release
- 1 capsule (120 mg) by oral route once daily
verapamil ER 180 mg 24 hr capsule,extended release
- 1 capsule (180 mg) by oral route once daily
verapamil ER 240 mg 24 hr capsule,extended release
- 1 capsule (240 mg) by oral route once daily
verapamil ER 360 mg 24 hr capsule,extended release
- 1 capsule (360 mg) by oral route once daily
ER 120 mg 24 hr capsule,extended release
- 1 capsule (120 mg) by oral route once daily
ER 180 mg 24 hr capsule,extended release
- 1 capsule (180 mg) by oral route once daily
ER 240 mg 24 hr capsule,extended release
- 1 capsule (240 mg) by oral route once daily
ER 360 mg 24 hr capsule,extended release
- 1 capsule (360 mg) by oral route once daily
(SR) 120 mg tablet,extended release
- 1 tablet (120 mg) by oral route once daily with food
(SR) 180 mg tablet,extended release
- 1 tablet (180 mg) by oral route once daily with food
(SR) 240 mg tablet,extended release
- 1 tablet (240 mg) by oral route once daily with food
120 mg tablet,extended release
- 1 tablet (120 mg) by oral route once daily with food
180 mg tablet,extended release
- 1 tablet (180 mg) by oral route once daily with food
240 mg tablet,extended release
- 1 tablet (240 mg) by oral route once daily with food
Hypertension
- 1 capsule (120 mg) by oral route once daily
- 1 tablet (120 mg) by oral route once daily with food
- 1 tablet (120 mg) by oral route 2 times per day with food
- 1 tablet (120 mg) by oral route every 12 hours with food
- 1 tablet (180 mg) by oral route once daily with food
- 1 tablet (180 mg) by oral route 2 times per day with food
- 1 tablet (180 mg) by oral route every 12 hours with food
- 1 capsule (180 mg) by oral route once daily
- 1 capsule (240 mg) by oral route once daily
- 2 capsules (240 mg) by oral route once daily
- 1 tablet (240 mg) by oral route once daily with food
- 2 tablets (240 mg) by oral route 2 times per day with food
- 2 tablets (240 mg) by oral route once daily with food
- 2 tablets (240 mg) by oral route every 12 hours with food
- 2 capsules (360 mg) by oral route once daily
- 2 capsules (480 mg) by oral route once daily
- dofetilide
- ezetimibe-simvastatin
- Juxtapid
- lomitapide
- niacin-simvastatin
- Simcor
- Tikosyn
- Vytorin 10-20
- Vytorin 10-40
- Vytorin 10-80
Contraindicated
- abobotulinumtoxinA
- amiodarone
- amiodarone in dextrose,iso-osm
- amoxicil-clarithromy-lansopraz
- Anectine
- Anzemet
- atracurium
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- Bosulif
- bosutinib
- Botox
- Botox Cosmetic
- cisatracurium
- clarithromycin
- colchicine
- colchicine-probenecid
- Colcrys
- Cordarone
- Dantrium
- dantrolene
- Digox
- digoxin
- dolasetron
- Dysport
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- fingolimod
- Gilenya
- guanfacine
- Hycamtin
- ibrutinib
- Imbruvica
- incobotulinumtoxinA
- Intuniv Er
- Ketek
- Lanoxin
- Lanoxin Pediatric
- midazolam
- midazolam (PF)
- Myobloc
- Nexterone
- Nimbex
- Olysio
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- onabotulinumtoxinA
- Orap
- Pacerone
- pancuronium
- pimozide
- Prevpac
- Quelicin
- Revonto
- rimabotulinumtoxinB
- rocuronium
- Samsca
- simeprevir
- succinylcholine chloride
- telithromycin
- Tenex
- tizanidine
- tolvaptan
- topotecan
- triazolam
- vecuronium bromide
- Xeomin
- Zanaflex
- Zemuron
Severe
Moderate
- Abstral
- acebutolol
- Actiq
- Advicor
- afatinib
- Afinitor
- Afinitor Disperz
- Alfenta
- alfentanil
- aliskiren
- aliskiren-amlodipin-hcthiazide
- aliskiren-amlodipine
- aliskiren-hydrochlorothiazide
- Altoprev
- amlodipine-atorvastatin
- Amturnide
- Anti-diarrhea
- Anti-diarrheal (lope)-anti-gas
- Anti-diarrheal (loperamide)
- Astagraf Xl
- atenolol
- atenolol-chlorthalidone
- atorvastatin
- avanafil
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Betapace
- Betapace Af
- Betimol
- boceprevir
- bosentan
- brimonidine-timolol
- buspirone
- Bystolic
- Caduet
- calcium-mag-B complex-D3-hrb61
- carbamazepine
- Carbatrol
- cilostazol
- Cold & Flu Fighter
- Combigan
- Corgard
- Corzide
- Cosopt
- Cosopt Pf
- cyclosporine
- cyclosporine modified
- dextromethorphan-quinidine
- Diamode
- dorzolamide-timolol
- dorzolamide-timolol (PF)
- dronedarone
- Duragesic
- dutasteride-tamsulosin
- Dutoprol
- Endocet
- Endodan
- Epitol
- eplerenone
- Equetro
- Etopophos
- etoposide
- etoposide phosphate
- everolimus
- ezetimibe-atorvastatin
- Fatigue Relief Complex
- fentanyl
- fentanyl citrate
- fentanyl citrate (PF)
- Fentora
- Flomax
- Gengraf
- Gilotrif
- Hecoria
- ibuprofen-oxycodone
- Imodium Multi-symptom Relief
- Incivek
- Inderal La
- Inderal Xl
- Innopran Xl
- Inspra
- isoniazid-rifamp-pyrazinamide
- Istalol
- ivacaftor
- Jalyn
- Kalydeco
- ketoconazole
- labetalol
- Latuda
- Lazanda
- Levitra
- Lipitor
- Liptruzet
- Lo-peramide
- loperamide
- loperamide-simethicone
- Lopressor
- Lopressor Hct
- lovastatin
- lurasidone
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Mevacor
- Minipress
- Multaq
- Mycobutin
- nadolol
- nadolol-bendroflumethiazide
- nebivolol
- Neoral
- niacin-lovastatin
- Nuedexta
- Oxecta
- oxycodone
- oxycodone-acetaminophen
- oxycodone-aspirin
- Oxycontin
- Percocet
- Percodan
- pindolol
- Pletal
- prazosin
- Priftin
- Primlev
- Prograf
- propranolol
- propranolol-hydrochlorothiazid
- quinidine gluconate
- quinidine sulfate
- Rapamune
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- Roxicet
- Sandimmune
- Sectral
- simvastatin
- sirolimus
- Sorine
- sotalol
- Sotalol Af
- St. John's wort
- Stendra
- Sublimaze (pf)
- Subsys
- tacrolimus
- tamsulosin
- Tegretol
- Tegretol Xr
- Tekamlo
- Tekturna
- Tekturna Hct
- telaprevir
- temsirolimus
- Tenoretic 100
- Tenoretic 50
- Tenormin
- terazosin
- timolol
- timolol maleate
- timolol maleate (PF)
- Timoptic
- Timoptic Ocudose (pf)
- Timoptic-xe
- Toposar
- Toprol Xl
- Torisel
- Tracleer
- Trandate
- Ultra A-d
- vardenafil
- Victrelis
- vit C-St. John wort-elder-hb30
- Vytorin 10-10
- Women's Complex
- Xartemis Xr
- Zocor
- Zortress
- Cardiogenic shock
- Complete atrioventricular block
- Low cardiac output
- Lown-ganong-levine syndrome
- Second degree atrioventricular heart block
- Severe chronic heart failure
- Severe hypotension
- Wolff-parkinson-white pattern
Contraindicated
- Abnormal hepatic function tests
- Bradycardia
- Chronic idiopathic constipation
- Duchenne muscular dystrophy
- First degree atrioventricular heart block
- Hypotension
- Left ventricular failure
- Myasthenia gravis
- Neuromuscular transmission deficiency
- Sick sinus syndrome
- Ventricular tachycardia
Severe
Moderate
- Disease of liver
- Kidney disease with reduction in GFR
VERAPAMIL ER (verapamil HCl)
- Hypertension
- None
- Constipation
- Dizziness
- Flu-like symptoms
- Headache disorder
- Infection
- Peripheral edema
- Pharyngitis
- Sinusitis
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Bradycardia
- Chronic heart failure
- Dyspnea
- Hypotension
- Pulmonary edema
- Edema
- Fatigue
- Nausea
- Rhinitis
- Skin rash
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal ECG
- Abnormal hepatic function tests
- Acute myocardial infarction
- Atrioventricular block
- Cerebrovascular accident
- Drug-induced psychosis
- Erythema multiforme
- Extrapyramidal disease
- Galactorrhea not associated with childbirth
- Gingival hyperplasia
- Hepatocellular damage
- Hyperbilirubinemia
- Hyperprolactinemia
- Increased alanine transaminase
- Increased aspartate transaminase
- Severe hypotension
- Stevens-johnson syndrome
Less Severe
- Acute confusion
- Alopecia
- Arthralgias
- Blurred vision
- Cramps
- Diarrhea
- Drowsy
- Dyspepsia
- Ecchymosis
- Erectile dysfunction
- Flushing
- General weakness
- Gynecomastia
- Increased urinary frequency
- Insomnia
- Menstrual disorder
- Palpitations
- Paresthesia
- Purpura
- Tinnitus
- Tremor
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Verapamil (Oral)
Safety and efficacy of oral dose form not established. Dosing guidelines available.
- 1 Day – 18 Years
- Safety and efficacy of oral dose form not established. Dosing guidelines available.
Verapamil Hydrochloride
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Verapamil Hydrochloride
Limited data suggest infant levels are low with no resulting adverse effects
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Limited data suggest infant levels are low with no resulting adverse effects |
Contraindicated
None
Precaution Exists
Verapamil
Cardiovascular-Elderly are more sensitive to blood pressure lowering effects and may have lower drug clearance. Start at lower doses and titrate upward more slowly. May promote fluid retention and exacerbate heart failure. Gastrointestinal-may cause or worsen pre-existing constipation.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- None
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool