TOPROL XL (metoprolol succinate)

Moderate

• Aceta-gesic

• Acetadryl

• Acetaminophen Pm

• Acetaminophen Pm Extra Str

• Acid Control (ranitidine)

• Acid Reducer (cimetidine)

• Acid Reducer (ranitidine)

• Acid Relief (cimetidine)

• Adalat Cc

• Adult Robitussin Night M-s Cld

• Advil

• Advil Allergy Sinus

• Advil Allergy-congestion Rlf

• Advil Cold & Sinus

• Advil Congestion Relief

• Advil Liqui-gel

• Advil Migraine

• Advil Pm

• Advil Pm Liqui-gels

• Afeditab Cr

• Alagesic Lq

• Aldex-ct

• Aler-cap

• Aler-tab

• Aleve

• Aleve Cold & Sinus

• Aleve Sinus & Headache

• Aleve-d Sinus & Cold

• Aleve-d Sinus & Headache

• Alka-seltzer Plus Allergy

• Alka-seltzer Pm

• All Day Pain Relief

• All Day Pain Relief Sinus & Co

• All Day Relief

• Aller-g-time

• Allergy (diphenhydramine)

• Allergy M-s Nighttime

• Allergy Medication

• Allergy Medicine

• Allergy Plus Severe Sinus Ha

• Allergy Relief(diphenhydramin)

• Allergy Relief-sinus Headache

• Allergy Severe

• Allergy Sinus Headache

• Allergy-d

• Allergy-sinus

• Altavera (28)

• Alyacen 1/35 (28)

• Alyacen 7/7/7 (28)

• Amethia

• Amethia Lo

• Amethyst

• amiodarone

• amiodarone in dextrose,iso-osm

• amobarbital

• Amytal

• Anaprox

• Anaprox Ds

• Ansaid

• Antihist

• Antihistamine

• Aplenzin

• Apri

• Aranelle (28)

• Ascomp With Codeine

• aspirin-diphenhydramine

• aspirin-diphenhydramine citrat

• Aubra

• Aviane

• Azurette (28)

• Balziva (28)

• Banophen

• Banophen Allergy

• Bayer Pm

• Belladonna-phenobarbital

• Belviq

• Benadryl

• Benadryl Allergy

• Beyaz

• Brevicon (28)

• Briellyn

• Brisdelle

• Bupap

• Buproban

• bupropion HBr

• bupropion HCl

• butabarbital

• Butalbital Compound W/codeine

• Butalbital Compound-codeine

• butalbital-acetaminop-caf-cod

• butalbital-acetaminophen

• butalbital-acetaminophen-caff

• butalbital-aspirin-caffeine

• Butisol

• Calan

• Calan Sr

• Caldolor

• Camila

• Camrese

• Camrese Lo

• Capacet

• Cardizem

• Cardizem Cd

• Cardizem La

• Cartia Xt

• Caziant (28)

• Celebrex

• celecoxib

• Celexa

• Chateal

• Child Allergy Relief (diphen)

• Child Delsym Cough+cold

• Child Ibuprofen

• Child's Benadryl-d Allergy-sin

• Children Night Time Cold-cough

• Children's Advil

• Children's Allergy

• Children's Complete Allergy

• Children's Ibu-drops

• Children's Ibuprofen

• Children's Medi-profen

• Children's Motrin

• Children's Mucinex Night Time

• Children's Profen Ib

• Children's Wal-dryl Allergy

• Childs Plus Cold & Allergy

• Childs Triacting Cold & Cough

• chlorphen-phenyleph-ibuprofen

• chlorphen-pseudoeph-ibuprofen

• cimetidine

• cinacalcet

• citalopram

• codeine-butalbital-ASA-caff

• Cold & Cough

• Cold & Sinus Pain Relief

• Cold Relief

• Cold-sinus Relief

• Complete Allergy

• Complete Allergy Medicine

• Compoz

• conj estrogens-bazedoxifene

• Cordarone

• Cough & Severe Cold

• Cryselle (28)

• Cyclafem 1/35 (28)

• Cyclafem 7/7/7 (28)

• Cyclessa (28)

• Cymbalta

• Dasetta 1/35 (28)

• Dasetta 7/7/7 (28)

• Daysee

• Delsym Cough+cold Nighttime

• Depo-provera

• Depo-subq Provera 104

• Deprizine

• desog-e.estradiol/e.estradiol

• Desogen

• desogestrel-ethinyl estradiol

• dextromethorphan-quinidine

• Diabetic Tussin Night Time

• Dicopanol

• Dilacor Xr

• Dilt-xr

• diltiazem HCl

• Dimetapp Cold-congestion

• Diphedryl

• Diphedryl Allergy

• Diphenhist

• diphenhy HCl-PE-DM-acetamin-GG

• diphenhyd-PE-acetaminophen

• diphenhyd-PE-DM-acetaminophen

• diphenhydram-PE-acetaminoph-GG

• diphenhydram-PSE-acetaminophen

• diphenhydramine HCl

• diphenhydramine-acetaminophen

• diphenhydramine-DM-acetamin

• diphenhydramine-phenylephrine

• Donnatal

• dronedarone

• drospirenone-e.estradiol-lm.FA

• drospirenone-ethinyl estradiol

• Duavee

• Duexis

• duloxetine

• Ec-naprosyn

• Elinest

• Emoquette

• Enpresse

• Enskyce

• Errin

• escitalopram oxalate

• Esgic

• Estarylla

• estradiol valerate-dienogest

• Estrostep Fe-28

• ethynodiol diac-eth estradiol

• etonogestrel

• etonogestrel-ethinyl estradiol

• Ex-strength Medi-tabs Pm

• Ez Nite Sleep

• Ez Use Joint-tunnel-trigger

• Falmina (28)

• Feldene

• Femcon Fe

• Fioricet

• Fioricet With Codeine

• Fiorinal

• Fiorinal-codeine #3

• First-bxn

• First-duke's

• First-mary's Mouthwash

• Flanax

• Flu & Severe Cold-nighttime

• Flu & Sore Throat Relief

• Flu Formula Daytime-nighttime

• Flu Relief Therapy Nighttime

• Flu-severe Cold-cough

• fluoxetine

• flurbiprofen

• Forfivo Xl

• Generess Fe

• Gianvi (28)

• Gildagia

• Gildess

• Gildess Fe

• Gleevec

• Goody's Pm

• Headache Pm

• Headache Relief Pm

• Heartburn Relief

• Heartburn Relief (ranitidine)

• Heather

• hydrocodone-ibuprofen

• hydroxychloroquine

• I-prin

• Ibu-drops

• Ibudone

• ibuprofen

• Ibuprofen Cold

• Ibuprofen Cold-sinus(with Pse)

• Ibuprofen Ib

• Ibuprofen Jr Strength

• ibuprofen lysine (PF)

• Ibuprofen Pm

• ibuprofen-diphenhydramine

• ibuprofen-diphenhydramine HCl

• ibuprofen-famotidine

• ibuprofen-oxycodone

• ibuprofen-phenylephrine HCl

• imatinib

• Indocin

• indomethacin

• indomethacin sodium

• Infant's Ibuprofen

• Infant's Medi-profen

• Infant's Motrin

• Infants Ibu-drops

• Infants Profenib

• Intense Cold & Flu

• Introvale

• isoniazid-rifamp-pyrazinamide

• Jencycla

• Jolessa

• Jolivette

• Junel 1.5/30 (21)

• Junel 1/20 (21)

• Junel Fe 1.5/30 (28)

• Junel Fe 1/20 (28)

• Kariva (28)

• Kelnor 1/35 (28)

• Kurvelo

• L norgest&E estradiol-E estrad

• Lamisil

• Larin 1/20 (21)

• Larin Fe

• Leena 28

• Lessina

• Levonest (28)

• levonorg-eth estrad triphasic

• levonorgestrel

• levonorgestrel-ethinyl estrad

• Levora 0.15/30 (28)

• Levora-28

• Lexapro

• lidocaine (PF)

• lidocaine in D5W (PF)

• Lo Loestrin Fe

• Loestrin 1.5/30 (21)

• Loestrin 1/20 (21)

• Loestrin Fe 1.5/30 (28)

• Loestrin Fe 1/20 (28)

• Lomedia 24 Fe

• lorcaserin

• Loryna (28)

• Loseasonique

• Low-ogestrel (28)

• Luminal

• Lutera (28)

• Lyza

• Mapap Pm

• Margesic

• Marlissa

• Marten-tab

• Matzim La

• Medi-phedryl

• Medi-profen

• Medi-tabs Pm

• Mediproxen

• medroxyprogesterone

• mefloquine

• meloxicam

• Microgestin 1.5/30 (21)

• Microgestin 1/20 (21)

• Microgestin Fe 1.5/30 (28)

• Microgestin Fe 1/20 (28)

• Midol (naproxen)

• Midol Pm

• Minastrin 24 Fe

• Minipress

• mirabegron

• Mircette (28)

• Mirena

• Mobic

• Modicon (28)

• Mono-linyah

• Mononessa (28)

• Motrin Ib

• Motrin Pm

• Mucinex Fast-max Nite Cold-flu

• Mucinex Sinus-max Day-night

• Multaq

• My Way

• Mycobutin

• Myrbetriq

• Mysoline

• Myzilra

• Naprelan Cr

• Naprosyn

• naproxen

• naproxen sodium

• naproxen-esomeprazole

• naproxen-pseudoephedrine

• Natazia

• Necon 0.5/35 (28)

• Necon 1/35 (28)

• Necon 1/50 (28)

• Necon 10/11 (28)

• Necon 7/7/7 (28)

• Nembutal Sodium

• Neoprofen (ibuprofen Lysn)(pf)

• Nexplanon

• Next Choice One Dose

• Nexterone

• Nifedical Xl

• nifedipine

• Nightime Sleep

• Nighttime Cough-cold

• Nighttime Sleep Aid (diphen)

• Non-asa Ex St Pain/sleep Aid

• Non-aspirin Allergy Sinus Pm

• Non-aspirin Flu

• Non-aspirin Nightime

• Non-aspirin Pain Relief Pm

• Non-aspirin Pm

• Nor-qd

• Nora-be

• norelgestrom-ethinyl estradiol

• noreth-ethinyl estradiol-iron

• norethin-e.estradiol triphasic

• norethin-eth estrad biphasic

• norethindrone (contraceptive)

• norethindrone ac-eth estradiol

• norethindrone-e.estradiol-iron

• norethindrone-ethin estradiol

• norethindrone-mestranol

• norgestimate-ethinyl estradiol

• norgestrel-ethinyl estradiol

• Norinyl 1+35 (28)

• Norinyl 1+50 (28)

• Nortrel 0.5/35 (28)

• Nortrel 1/35 (21)

• Nortrel 1/35 (28)

• Nortrel 7/7/7 (28)

• Nuedexta

• Nuvaring

• nystat-lidocaine-diphenhyd HCl

• nystatin-hydrocortisone-diphen

• nystatin-TCN-HC-diphenhydramin

• Nytol

• Ocella

• Ogestrel (28)

• olanzapine-fluoxetine

• Ormir

• Orsythia

• Ortho Evra

• Ortho Micronor

• Ortho Tri-cyclen (28)

• Ortho Tri-cyclen Lo (28)

• Ortho-cept (28)

• Ortho-cyclen (28)

• Ortho-novum 1/35 (28)

• Ortho-novum 7/7/7 (28)

• Ovcon-35 (28)

• Pacerone

• Pain & Sleep

• Pain Medicine P.m.

• Pain Relief Pm

• Pain Relief Pm Rapid Release

• Pain Reliever Am/pm

• Pain Reliever Pm

• Pain Reliever Pm Ex-strength

• paroxetine HCl

• paroxetine mesylate

• Paxil

• Paxil Cr

• pentobarbital sodium

• Percogesic

• Percogesic Extra Strength

• Pexeva

• Pharbedryl

• phenobarb-hyoscy-atropine-scop

• phenobarbital

• phenobarbital sodium

• Philith

• Pimtrea (28)

• Pirmella

• piroxicam

• Plan B One-step

• Plaquenil

• Pm Pain Reliever

• Portia

• prazosin

• Previfem

• Priftin

• primidone

• Procardia

• Procardia Xl

• propafenone

• Provil

• Prozac

• Prozac Weekly

• pseudoephedrine-ibuprofen

• Q-dryl

• Quartette

• Quasense

• Quenalin

• quinidine gluconate

• quinidine sulfate

• ranitidine HCl

• Reclipsen (28)

• Reprexain

• Rest Simply Nighttime Sleep

• Restfully Sleep

• rifabutin

• Rifadin

• Rifamate

• rifampin

• rifampin-isoniazid

• rifapentine

• Rifater

• Rythmol

• Safyral

• Sarafem

• Seasonique

• secobarbital sodium

• Seconal Sodium

• Sensipar

• sertraline

• Severe Allergy

• Severe Allergy-sinus Headache

• Severe Cold (diphen-pe-acetam)

• Severe Cold Pe

• Siladryl Sa

• Silphen Cough

• Simply Sleep

• Sinus & Cold-d

• Sleep

• Sleep Aid (diphenhydramine)

• Sleep Aid Max Str (diphenhydr)

• Sleep Ii

• Sleep Tablet (diphenhydramine)

• Sleep Time

• Sleep-tabs

• Sleepgels

• Sleeping

• Sprintec (28)

• Sronyx

• sulindac

• Suphedrine Pe Day-night

• Syeda

• Symbyax

• Tagamet Hb

• Tarka

• Taztia Xt

• Tencon

• terbinafine

• Theraflu Nighttime Cold-cough

• Tiazac

• Tilia Fe

• trandolapril-verapamil

• Tri-estarylla

• Tri-legest Fe

• Tri-linyah

• Tri-norinyl (28)

• Tri-previfem (28)

• Tri-sprintec (28)

• triamcinolone-lidocaine

• Triaminic Cold & Cough Nt (pe)

• Trinessa (28)

• Trivora (28)

• Unisom Sleepgels

• Unisom Sleepmelts

• Valu-dryl

• Valu-dryl Allergy

• Valu-dryl Allergy-sinus-head

• Valu-dryl Child's Allergy

• Velivet Triphasic Regimen (28)

• verapamil

• Verelan

• Verelan Pm

• Vestura (28)

• Vicoprofen

• Vimovo

• Viorele (28)

• Vyfemla (28)

• Wal-dryl Allergy

• Wal-dryl Severe Allergy-sinus

• Wal-dryl-d Allergy & Sinus

• Wal-flu Night Severe Cold

• Wal-nadol Pm

• Wal-phed Pe Nighttime Cold

• Wal-phed Pe Severe Cold

• Wal-profen

• Wal-profen Cold-sinus

• Wal-proxen

• Wal-sleep Z

• Wal-som

• Wal-zan 150

• Wellbutrin

• Wellbutrin Sr

• Wellbutrin Xl

• Wera (28)

• Wymzya Fe

• Xylocaine (cardiac) (pf)

• Yasmin (28)

• Yaz 28

• Z-sleep

• Zantac

• Zantac Maximum Strength

• Zarah

• Zebutal

• Zenchent (28)

• Zenchent Fe

• Zeosa

• Zoloft

• Zovia 1/35E (28)

• Zovia 1/50E (28)

• Zyban

• Zzzquil

Moderate

• Bronchospastic pulmonary disease

• Depression

• Diabetes mellitus

• Hypoglycemic disorder

• Myasthenia gravis

• Pheochromocytoma

• Psoriasis

• Raynaud's phenomenon

Metoprolol

• Severity Level:

  2

• Additional Notes: Insufficient human data avail on dev tox risk; weigh maternal benefit vs. risks

Contraindicated

None

General	Excretion Potential	Effect on Infant	Notes
			None

Precaution Exists

Metoprolol

Limited data suggest minimal excretion; monitor for bradycardia & hypotension

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Limited data suggest minimal excretion; monitor for bradycardia & hypotension

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Metoprolol

Cardiovascular-Minimize dose to decrease dizziness and falls. Worsening cardiac failure may occur during up-titration of beta-blockers.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	N	N	N	N	N	N

BEERS: N     HEDIS: N     STOPP: Y

No Known Risk

None

0-9	A-Z
I10	Essential (primary) hypertension
I11	Hypertensive heart disease
I11.0	Hypertensive heart disease with heart failure
I11.9	Hypertensive heart disease without heart failure
I12	Hypertensive chronic kidney disease
I12.0	Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease
I12.9	Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13	Hypertensive heart and chronic kidney disease
I13.0	Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.1	Hypertensive heart and chronic kidney disease without heart failure
I13.10	Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.11	Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease
I13.2	Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease
I15.1	Hypertension secondary to other renal disorders
I20.2	Refractory angina pectoris
I20.81	Angina pectoris with coronary microvascular dysfunction
I20.89	Other forms of angina pectoris
I20.9	Angina pectoris, unspecified
I25.112	Atherosclerotic heart disease of native coronary artery with refractory angina pectoris
I25.118	Atherosclerotic heart disease of native coronary artery with other forms of angina pectoris
I25.119	Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris
I25.702	Atherosclerosis of coronary artery bypass graft(s), unspecified, with refractory angina pectoris
I25.708	Atherosclerosis of coronary artery bypass graft(s), unspecified, with other forms of angina pectoris
I25.709	Atherosclerosis of coronary artery bypass graft(s), unspecified, with unspecified angina pectoris
I25.712	Atherosclerosis of autologous vein coronary artery bypass graft(s) with refractory angina pectoris
I25.718	Atherosclerosis of autologous vein coronary artery bypass graft(s) with other forms of angina pectoris
I25.719	Atherosclerosis of autologous vein coronary artery bypass graft(s) with unspecified angina pectoris
I25.722	Atherosclerosis of autologous artery coronary artery bypass graft(s) with refractory angina pectoris
I25.728	Atherosclerosis of autologous artery coronary artery bypass graft(s) with other forms of angina pectoris
I25.729	Atherosclerosis of autologous artery coronary artery bypass graft(s) with unspecified angina pectoris
I25.732	Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with refractory angina pectoris
I25.738	Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with other forms of angina pectoris
I25.739	Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unspecified angina pectoris
I25.752	Atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris
I25.758	Atherosclerosis of native coronary artery of transplanted heart with other forms of angina pectoris
I25.759	Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris
I25.762	Atherosclerosis of bypass graft of coronary artery of transplanted heart with refractory angina pectoris
I25.768	Atherosclerosis of bypass graft of coronary artery of transplanted heart with other forms of angina pectoris
I25.769	Atherosclerosis of bypass graft of coronary artery of transplanted heart with unspecified angina pectoris
I25.792	Atherosclerosis of other coronary artery bypass graft(s) with refractory angina pectoris
I25.798	Atherosclerosis of other coronary artery bypass graft(s) with other forms of angina pectoris
I25.799	Atherosclerosis of other coronary artery bypass graft(s) with unspecified angina pectoris
I50.22	Chronic systolic (congestive) heart failure
I50.32	Chronic diastolic (congestive) heart failure
I50.42	Chronic combined systolic (congestive) and diastolic (congestive) heart failure
I50.812	Chronic right heart failure
I50.814	Right heart failure due to left heart failure