PROBENECID (PROBENECID)

Moderate

• abacavir-lamivudine-zidovudine

• acetaminophen-mag sal-pamabrom

• Added Strength Headache Relief

• Added Strength Pain Reliever

• Adult Low Dose Aspirin

• Advil

• Advil Allergy Sinus

• Advil Allergy-congestion Rlf

• Advil Cold & Sinus

• Advil Congestion Relief

• Advil Liqui-gel

• Advil Migraine

• Advil Pm

• Advil Pm Liqui-gels

• Aggrenox

• Aleve

• Aleve Cold & Sinus

• Aleve Sinus & Headache

• Aleve-d Sinus & Cold

• Aleve-d Sinus & Headache

• Alka-seltzer

• Alka-seltzer Extra Strength

• Alka-seltzer Original

• Alka-seltzer Plus C/c(pe,dm)

• Alka-seltzer Plus Cold (pe)

• Alka-seltzer Plus Day-night

• Alka-seltzer Plus Night

• Alka-seltzer Pm

• All Day Pain Relief

• All Day Pain Relief Sinus & Co

• All Day Relief

• Anacin

• Anacin Maximum Strength

• Analgesic

• Anaprox

• Anaprox Ds

• Ansaid

• Antacid & Pain Relief

• Apriso

• Arthri-flex

• Arthrotec 50

• ASA-acetaminophen-caff-buffers

• ASA-acetaminophen-salicyl-caff

• Asacol Hd

• Ascomp With Codeine

• Aspir-81

• Aspir-low

• Aspir-trin

• aspirin

• Aspirin Childrens

• Aspirin Low Dose

• Aspirin Low-strength

• aspirin, buffered

• aspirin-acetaminophen-caffeine

• aspirin-caffeine

• aspirin-calcium carbonate

• aspirin-diphenhydramine

• aspirin-diphenhydramine citrat

• aspirin-sod bicarb-citric acid

• Ativan

• Back & Body Pain Reliever

• Back Pain-off

• Backache Relief

• Backache Relief Extra Strength

• balsalazide

• Bayer Advanced

• Bayer Aspirin

• Bayer Aspirin (with Caffeine)

• Bayer Back & Body

• Bayer Chewable Aspirin

• Bayer Childrens Aspirin

• Bayer Plus Extra Strength

• Bayer Pm

• Bc

• Bc Arthritis

• Bismatrol

• Bismuth

• Bismuth Maximum Strength

• bismuth subsalicylate

• Buffered Aspirin

• Bufferin

• Butalbital Compound W/codeine

• Butalbital Compound-codeine

• butalbital-aspirin-caffeine

• Caldolor

• Cambia

• Canasa

• carisoprodol-ASA-codeine

• carisoprodol-aspirin

• Cataflam

• Cedax

• cefaclor

• cefadroxil

• cefazolin

• cefazolin in dextrose (iso-os)

• cefdinir

• cefepime

• cefepime in dextrose 5 %

• cefepime in dextrose,iso-osm

• cefotaxime

• cefotetan

• cefotetan in dextrose, iso-osm

• cefoxitin

• cefoxitin in dextrose 3.9 %

• cefoxitin in dextrose, iso-osm

• cefpodoxime

• cefprozil

• ceftibuten

• Ceftin

• cefuroxime axetil

• cefuroxime in sterile water

• cefuroxime sodium

• cefuroxime-dextrose (iso-osm)

• Celebrex

• celecoxib

• cephalexin

• Child Aspirin

• Child Ibuprofen

• Children's Advil

• Children's Aspirin

• Children's Ibu-drops

• Children's Ibuprofen

• Children's Medi-profen

• Children's Motrin

• Children's Profen Ib

• chlorphen-phenyleph-DM-aspirin

• chlorphen-phenyleph-ibuprofen

• chlorphen-pseudoeph-ibuprofen

• chlorphenir-phenylephrn-aspirn

• choline & magnesium salicylate

• Claforan

• codeine-butalbital-ASA-caff

• Colazal

• Cold & Sinus Pain Relief

• Cold Relief

• Cold Relief Plus

• Cold-sinus Relief

• Combivir

• Cystex (methenamine & Sod Sal)

• Delzicol

• Diarrhea Relief (bismuth Subs)

• diclofenac epolamine

• diclofenac potassium

• diclofenac sodium

• diclofenac submicronized

• diclofenac-misoprostol

• dihydrocodeine-aspirin-caff

• Diotame

• Diotame Instydose

• Dipentum

• dipyridamole-aspirin

• doxylamine-phenylep-DM-aspirin

• Duexis

• dyphylline

• E.c. Prin

• Ec-naprosyn

• Ecotrin

• Ecotrin Low Strength

• Efferves Pain Relief Antacid

• Effervescent Antacid

• Effervescent Pain Relief

• Effervescent Pain Reliever

• Endodan

• Enteric Coated Aspirin

• etodolac

• Excedrin Extra Strength

• Excedrin Migraine

• Extra Strength Bayer

• Feldene

• fenoprofen

• Fiorinal

• Fiorinal-codeine #3

• Flanax

• Flector

• flurbiprofen

• Giazo

• gluc-msm-coll2-hyal-antiarthr3

• glucos-msm-C-Mn-ginger-willow

• glucos-msm-C-Mn-herb#21

• glucos-msm-collagen-C-Mn-hrb21

• Glucosamine-msm Complex

• Goody's Extra Strength

• Goody's Migraine Relief

• Headache Formula

• Headache Formula Added Str

• Headache Relief

• hydrocodone-ibuprofen

• Hyophen

• I-prin

• Ibu-drops

• Ibudone

• ibuprofen

• Ibuprofen Cold

• Ibuprofen Cold-sinus(with Pse)

• Ibuprofen Ib

• Ibuprofen Jr Strength

• ibuprofen lysine (PF)

• Ibuprofen Pm

• ibuprofen-diphenhydramine

• ibuprofen-diphenhydramine HCl

• ibuprofen-famotidine

• ibuprofen-oxycodone

• ibuprofen-phenylephrine HCl

• Indocin

• indomethacin

• indomethacin sodium

• Infant's Ibuprofen

• Infant's Medi-profen

• Infant's Motrin

• Infants Ibu-drops

• Infants Profenib

• K-pec Antidiarrheal (bism Sub)

• Kao-tin (bismuth Subsalicylat)

• Kaopectate (bismuth Subsalicy)

• Kaopectate Child(bis Ssalicyl)

• Kaopectate Ex Str (bismuth Ss)

• Keflex

• ketoprofen

• Kola-pectin Ds

• lamivudine-zidovudine

• Levacet

• Lialda

• Lite Coat Aspirin

• Lo-dose Aspirin

• lorazepam

• Lorazepam Intensol

• Lufyllin

• magnesium salicylate

• Maxipime

• Medi-bismuth

• Medi-profen

• Medi-seltzer

• Mediproxen

• Mefoxin In Dextrose (iso-osm)

• mesalamine

• mesalamine-cleansing wipes

• methen-hyos-me blue-ba-salicyl

• methen-hyosc-m.blue-sal-naphos

• methenamine-sodium salicylate

• Mg salicylat-acetaminophen-caf

• Midol (naproxen)

• Migraine Formula

• Migraine Pain Reliever

• Migraine Relief

• Motrin Ib

• Motrin Pm

• Msm Glucosamine Complex

• mth-me blue-sod phos-phsal-hyo

• nabumetone

• Nalfon

• Naprelan Cr

• Naprosyn

• naproxen

• naproxen sodium

• naproxen-esomeprazole

• naproxen-pseudoephedrine

• Neoprofen (ibuprofen Lysn)(pf)

• olsalazine

• Orphenadrine Compound Forte

• Orphenadrine Compound-ds

• orphenadrine-ASA-caffeine

• oxycodone-aspirin

• Pain Relief

• Pain Relief Extra Strength

• Pain Reliever

• Pain Reliever Extra Strength

• Pain Reliever Plus

• Pain-off

• Pamprin (with Mag Salicylate)

• Pamprin Max

• PE-DM-ASA/doxyla-PE-DM-ASA

• Pennsaid

• Pentasa

• Peptic Relief

• Pepto-bismol

• Pepto-bismol Max St

• Pepto-bismol To-go

• Percodan

• Phosphasal

• Pink Bismuth

• Pink Bismuth Maximum Strength

• piroxicam

• Prosed/ds (atropine Free)

• Provil

• pseudoephedrine-ibuprofen

• Reprexain

• Retrovir

• Rowasa

• salsalate

• Sfrowasa

• Sinus & Cold-d

• Solaraze

• Soothe (bismuth Subsalicylate)

• Soothe Regular Strength

• St Joseph Aspirin

• St. Joseph Aspirin

• Stomach Relief

• Stomach Relief Max Strength

• Stomach Relief Original

• sulindac

• Super Pain Relief

• Synalgos-dc

• tolmetin

• Tri-buffered Aspirin

• Trizivir

• Ur N-c

• Urelle

• Uretron D-s

• Uribel

• Urimar-t

• Urin Ds

• Ustell

• Uta

• Vanquish

• Vicoprofen

• Vimovo

• Voltaren-xr

• Wal-profen

• Wal-profen Cold-sinus

• Wal-proxen

• Women's Aspirin With Calcium

• zidovudine

• Zinacef

• Zinacef In Sterile Water

• Zipsor

• Zorvolex

Moderate

• Renal disease with mild to moderate impairment

Probenecid

• Severity Level:

  2

• Additional Notes: Limited human data; crosses placenta & present in cord blood

Contraindicated

None

General	Excretion Potential	Effect on Infant	Notes
			None

Precaution Exists

Probenecid

Insuff data avail; molecular wt low enough for possible breastmilk excretion

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Unknown	Not known; no or inclusive data	Insuff data avail; molecular wt low enough for possible breastmilk excretion

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Probenecid

General-Use with caution as adjunct to antibiotic therapy. Renal-Lack of efficacy CrCl < 30 mL/min.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	N	N	N	N

BEERS: Y     HEDIS: N     STOPP: N

No Known Risk

None

0-9	A-Z
E79.0	Hyperuricemia without signs of inflammatory arthritis and tophaceous disease
M10	Gout
M10.00	Idiopathic gout, unspecified site
M10.30	Gout due to renal impairment, unspecified site
M10.40	Other secondary gout, unspecified site
M10.9	Gout, unspecified
M1A.00x1	Idiopathic chronic gout, unspecified site, with tophus (tophi)
M1A.20x1	Drug-induced chronic gout, unspecified site, with tophus (tophi)
M1A.30x1	Chronic gout due to renal impairment, unspecified site, with tophus (tophi)
M1A.40x1	Other secondary chronic gout, unspecified site, with tophus (tophi)
M1A.9xx0	Chronic gout, unspecified, without tophus (tophi)
M1A.9xx1	Chronic gout, unspecified, with tophus (tophi)