Please wait while the formulary information is being retrieved.
MERCAPTOPURINE (MERCAPTOPURINE)
- Acute lymphoid leukemia
50 mg tablet
- 1.5 mg/kg by oral route once daily
Acute lymphoid leukemia
- 2.5 mg/kg by oral route once daily
- 1.5 mg/kg by oral route once daily
- 0.15 mg/kg by oral route once daily
- 0.25 mg/kg by oral route once daily
- 0.375 mg/kg by oral route once daily
- 0.495 mg/kg by oral route once daily
- 0.625 mg/kg by oral route once daily
- 0.825 mg/kg by oral route once daily
Acute myeloid leukemia
- 2.5 mg/kg by oral route once daily
- 1.5 mg/kg by oral route once daily
- 0.15 mg/kg by oral route once daily
- 0.25 mg/kg by oral route once daily
- 0.375 mg/kg by oral route once daily
- 0.495 mg/kg by oral route once daily
- 0.625 mg/kg by oral route once daily
- 0.825 mg/kg by oral route once daily
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- allopurinol
- allopurinol sodium
- Aloprim
- Azasan
- azathioprine
- azathioprine sodium
- BCG vaccine, live (PF)
- febuxostat
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- Imuran
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- organ preservation soln no.3
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- tofacitinib
- typhoid vaccine
- Tysabri
- Uloric
- varicella virus vacc live (PF)
- Varivax (pf)
- Viaspan (belzer Uw) Cold Ss
- Vivotif Berna Vaccine
- Xeljanz
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
- Zyloprim
Contraindicated
- adalimumab
- certolizumab pegol
- Cimzia
- Cimzia Powder For Reconst
- Cimzia Starter Kit
- clozapine
- Clozaril
- deferiprone
- Enbrel
- Enbrel Sureclick
- etanercept
- Fazaclo
- Ferriprox
- golimumab
- Humira
- Humira Crohn's Dis Start Pck
- Humira Pen
- Humira Psoriasis Starter Pack
- infliximab
- Remicade
- Simponi
- Simponi Aria
- Versacloz
Severe
Moderate
- Accupril
- Accuretic
- Aceon
- Altace
- amlodipine-benazepril
- Bactrim
- Bactrim Ds
- benazepril
- benazepril-hydrochlorothiazide
- captopril
- captopril-hydrochlorothiazide
- Copegus
- Coumadin
- enalapril maleate
- enalapril-hydrochlorothiazide
- enalaprilat
- Epaned
- fosinopril
- fosinopril-hydrochlorothiazide
- Jantoven
- lisinopril
- lisinopril-hydrochlorothiazide
- Lotensin
- Lotrel
- Mavik
- Moderiba
- Moderiba Dose Pack
- moexipril
- moexipril-hydrochlorothiazide
- perindopril erbumine
- Prinivil
- quinapril
- quinapril-hydrochlorothiazide
- ramipril
- Rebetol
- Ribapak Dose Pack
- Ribasphere
- Ribatab Dose Pack
- ribavirin
- sulfamethoxazole-trimethoprim
- Sulfatrim
- Tarka
- trandolapril
- trandolapril-verapamil
- Uniretic
- Univasc
- Vaseretic
- Vasotec
- Virazole
- warfarin
- Zestoretic
- Zestril
- Acute pancreatitis
- Hepatosplenic t-cell lymphoma
Contraindicated
- Abnormal hepatic function tests
- Anemia
- Ascites
- Disease of liver
- Gastrointestinal ulcer
- Kidney disease with reduction in GFR
- Leukopenia
- Neutropenic disorder
- Nucleotide diphosphatase (NUDt15) deficiency
- Pregnancy
- Thrombocytopenic disorder
- TPMT intermediate metabolizer
- TPMT poor metabolizer
Severe
Moderate
- Cholestasis
- Hyperbilirubinemia
MERCAPTOPURINE (MERCAPTOPURINE)
- Acute lymphoid leukemia
- Anemia
- Cholestasis
- Immunosuppression
- Infection
- Jaundice
- Leukopenia
- Neutropenic disorder
- Thrombocytopenic disorder
- Anorexia
- Diarrhea
- Malaise
- Skin rash
- Vomiting
More Frequent
Severe
Less Severe
- Abnormal hepatic function tests
- Chemotherapy-induced hyperuricemia
- Gastrointestinal ulcer
- Hyperbilirubinemia
- Stomatitis
- Uric acid nephropathy
- Alopecia
- General weakness
- Nausea
- Oligospermia
- Skin pigmentation enhancement
- Urticaria
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Hepatic necrosis
- Hepatosplenic t-cell lymphoma
- Lymphopenia
- Macrophage activation syndrome
- Pancreatitis
- Portal hypertension
- Pulmonary fibrosis
Less Severe
- Drug fever
- Hypoglycemic disorder
- Phototoxicity
Contraindicated
None
Severe Precaution
Mercaptopurine
Reports of symptomatic hypoglycemia age < 6 years.
- 1 Day – 6 Years
- Reports of symptomatic hypoglycemia age < 6 years.
Management or Monitoring Precaution
None
Mercaptopurine
- Severity Level:
D
- Additional Notes: Risk of abortion during 1st trimester;malformation risk not accurately known.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Mercaptopurine
Potential for serious adverse effects on infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Potential for serious adverse effects on infant |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Mercaptopurine
Renal-Reduce dose for CrCL<50 to minimize the higher risk for immunosuppression.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Acute lymphoid leukemia | |
| C91.0 | Acute lymphoblastic leukemia [ALl] |
| C91.00 | Acute lymphoblastic leukemia not having achieved remission |
| C91.02 | Acute lymphoblastic leukemia, in relapse |
| 0-9 | A-Z |
|---|---|
| C91.0 | Acute lymphoblastic leukemia [ALl] |
| C91.00 | Acute lymphoblastic leukemia not having achieved remission |
| C91.02 | Acute lymphoblastic leukemia, in relapse |
Formulary Reference Tool