Ovace Plus Shampoo

Drug overview for OVACE PLUS SHAMPOO (sulfacetamide sodium):

Generic name: sulfacetamide sodium (SUL-fa-SEET-a mide SOE dee um)
Drug class: Acne Antibiotics
Therapeutic class: Dermatological

No enhanced Introduction information available for this drug.

No enhanced Uses information available for this drug.

DRUG IMAGES

OVACE PLUS 10% SHAMPOO

The following indications for OVACE PLUS SHAMPOO (sulfacetamide sodium) have been approved by the FDA:

Indications:
Dandruff
Seborrheic dermatitis

Professional Synonyms:
Branny tetter
Dermatitis seborrheica
Dyssebacea
Dyssebacia
Pityriasis capitis
Pityriasis sicca
Pityriasis simplex
Scurf
Seborrhea corporis
Seborrhea furfuracea
Seborrhea sicca
Seborrheic eczema
Unna's disease

Dosing information for OVACE PLUS
DRUG LABEL	DOSING TYPE	DOSING INSTRUCTIONS
OVACE PLUS 10% SHAMPOO	Maintenance	Adults apply by topical route twice weekly to wet hair, massage vigorously into scalp and, then rinse thoroughly

Generic dosing information for SODIUM SULFACETAMIDE
DRUG LABEL	DOSING TYPE	DOSING INSTRUCTIONS
SOD SULFACETAMIDE 10% SHAMPOO	Maintenance	Adults apply by topical route twice weekly to wet hair, massage vigorously into scalp and, then rinse thoroughly

The following drug interaction information is available for OVACE PLUS SHAMPOO (sulfacetamide sodium):

Contraindicated
Severe
Moderate

There are 0 contraindications.

There are 1 severe interactions. These drug interactions can produce serious consequences in most patients. Actions required for severe interactions include, but are not limited to, discontinuing one or both agents, adjusting dosage, altering administration scheduling, and providing additional patient monitoring. Review the full interaction monograph for more information.

Drug Interaction	Drug Names
Topical Sodium Sulfacetamide/Topical Silver SEVERITY LEVEL: 2-Severe Interaction: Action is required to reduce the risk of severe adverse interaction. MECHANISM OF ACTION: Topical sodium sulfacetamide and topical silver are physically incompatible.(1,2) CLINICAL EFFECTS: Concurrent application of topical sodium sulfacetamide and topical silver preparations may result in decreased clinical effectiveness of the products.(1,2) PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: Avoid using topical silver preparations on the same location as topical sodium sulfacetamide products.(1,2) DISCUSSION: Topical sodium sulfacetamide and topical silver are physically incompatible.(1,2)	ACESO AG, ACTICOAT, ACTICOAT 7, ACTICOAT FLEX 3, ACTICOAT FLEX 7, ACTICOAT SURGICAL, ALLEVYN AG, ALLEVYN AG ADHESIVE, ALLEVYN AG GENTLE, AZADROX, BASADROX, BIOSTEP AG, COLLATYL, DYNAFOAM AG, DYNAGINATE AG, NORMLGEL AG, PIVOT SILVER ALGINATE, PURACOL PLUS AG, RESTORE, RESTORE CALCIUM ALGINATE, SILIGENTLE AG, SILVADENE, SILVASORB, SILVER NITRATE, SILVER NITRATE APPLICATOR, SILVER PROTEIN, SILVER SULFADIAZINE, SILVRSTAT, SOLOX GEL, SSD

Drug Interaction

Drug Names

Topical Sodium Sulfacetamide/Topical Silver

SEVERITY LEVEL: 2-Severe Interaction: Action is required to reduce the risk of severe adverse interaction.

MECHANISM OF ACTION: Topical sodium sulfacetamide and topical silver are physically incompatible.(1,2)

CLINICAL EFFECTS: Concurrent application of topical sodium sulfacetamide and topical silver preparations may result in decreased clinical effectiveness of the products.(1,2)

PREDISPOSING FACTORS: None determined.

PATIENT MANAGEMENT: Avoid using topical silver preparations on the same location as topical sodium sulfacetamide products.(1,2)

DISCUSSION: Topical sodium sulfacetamide and topical silver are physically incompatible.(1,2)

ACESO AG, ACTICOAT, ACTICOAT 7, ACTICOAT FLEX 3, ACTICOAT FLEX 7, ACTICOAT SURGICAL, ALLEVYN AG, ALLEVYN AG ADHESIVE, ALLEVYN AG GENTLE, AZADROX, BASADROX, BIOSTEP AG, COLLATYL, DYNAFOAM AG, DYNAGINATE AG, NORMLGEL AG, PIVOT SILVER ALGINATE, PURACOL PLUS AG, RESTORE, RESTORE CALCIUM ALGINATE, SILIGENTLE AG, SILVADENE, SILVASORB, SILVER NITRATE, SILVER NITRATE APPLICATOR, SILVER PROTEIN, SILVER SULFADIAZINE, SILVRSTAT, SOLOX GEL, SSD

There are 0 moderate interactions.

Contraindication List
Glucose-6-phosphate dehydrogenase (g6Pd) deficiency
Hemoglobin H disease
Hemolytic anemia from pyruvate kinase and g6PD deficiencies

More Frequent	Less Frequent
None.	None.

Rare/Very Rare
Agranulocytosis Blood dyscrasias Erythema Glucose-6-phosphate dehydrogenase (g6Pd) deficiency anemia Hepatic necrosis Hypersensitivity drug reaction Pruritus of skin Skin irritation Skin rash Stevens-johnson syndrome Systemic lupus erythematosus Toxic epidermal necrolysis

The following precautions are available for OVACE PLUS SHAMPOO (sulfacetamide sodium):

Pediatric
Pregnant
Lactation
Geriatric

No enhanced Pediatric Use information available for this drug.

Contraindicated

None

Severe Precaution

None

Management or Monitoring Precaution

None

No enhanced Pregnancy information available for this drug.

No enhanced Lactation information available for this drug.

No enhanced Geriatric Use information available for this drug.

Dandruff
L21.0	Seborrhea capitis
Seborrheic dermatitis
L21	Seborrheic dermatitis
L21.0	Seborrhea capitis
L21.1	Seborrheic infantile dermatitis
L21.8	Other seborrheic dermatitis
L21.9	Seborrheic dermatitis, unspecified