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PROVOCHOLINE (METHACHOLINE CHLORIDE)
- Diagnostic test for asthma
100 mg solution for inhalation
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- dextromethorphan-quinidine
- Nuedexta
- quinidine gluconate
- quinidine sulfate
- None
Contraindicated
- Bradycardia
- Increased gastric tonus
- Peptic ulcer
- Seizure disorder
- Urinary tract obstructive uropathy
Severe
Moderate
- None
PROVOCHOLINE (METHACHOLINE CHLORIDE)
- Diagnostic test for asthma
- None
- None
More Frequent
Severe
Less Severe
- None
- Dizziness
- Headache disorder
- Sore throat
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Chest tightness
- Dyspnea
- Wheezing
Less Severe
- Pruritus of skin
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Methacholine (Inhalation)
Safety and effectiveness not established in age < 5 years.
- 1 Day – 5 Years
- Safety and effectiveness not established in age < 5 years.
Methacholine
- Severity Level:
2
- Additional Notes: Insufficient human data available
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Methacholine
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- This medication must be used in a hospital or clinic setting under close medical supervision. It is only to be used for testing (challenge test) and should not be used to treat any conditions. Emergency equipment and medications must be available to reverse the effects of methacholine if you experience any breathing difficulties during or after the test. This drug is not recommended for use if you already have asthma, wheezing, or poor lung function test results before this challenge test.
Formulary Reference Tool