CANCIDAS (CASPOFUNGIN ACETATE)
- Candida peritonitis
- Candida pleural space infection
- Candidemia
- Esophageal candidiasis
- Febrile neutropenic patient presumed infection treatment
- Intra-abdominal candida abscess
- Refractory aspergillosis
50 mg intravenous solution
- Infuse 50 mg over 1 hour(s) by intravenous route once daily
70 mg intravenous solution
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
caspofungin 50 mg intravenous solution
- Infuse 50 mg over 1 hour(s) by intravenous route once daily
caspofungin 70 mg intravenous solution
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
50 mg intravenous solution
- Infuse 50 mg over 1 hour(s) by intravenous route once daily
70 mg intravenous solution
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
Candida peritonitis
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
- Infuse 50 mg over 60 minute(s) by intravenous route once daily for 14Days
- Infuse 70 mg over 60 minute(s) by intravenous route once daily
Candida pleural space infection
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
- Infuse 50 mg over 60 minute(s) by intravenous route once daily for 14Days
- Infuse 70 mg over 60 minute(s) by intravenous route once daily
Candidemia
- Infuse 50 mg over 1 hour(s) by intravenous route once daily
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
- Infuse 50 mg over 60 minute(s) by intravenous route once daily for 14Days
- Infuse 70 mg over 60 minute(s) by intravenous route once daily
Esophageal candidiasis
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
- Infuse 50 mg over 60 minute(s) by intravenous route once daily for 14Days
- Infuse 70 mg over 60 minute(s) by intravenous route once daily
Febrile neutropenic patient presumed infection treatment
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
- Infuse 50 mg over 60 minute(s) by intravenous route once daily for 14Days
- Infuse 70 mg over 60 minute(s) by intravenous route once daily
Intra-abdominal candida abscess
- Infuse 50 mg over 60 minute(s) by intravenous route once daily
- Infuse 50 mg over 60 minute(s) by intravenous route once daily for 14Days
- Infuse 70 mg over 60 minute(s) by intravenous route once daily
Refractory aspergillosis
- Infuse 50 mg by intravenous route once daily
- None
Contraindicated
- cyclosporine
- cyclosporine modified
- Gengraf
- Neoral
- Sandimmune
Severe
Moderate
- Astagraf Xl
- Atripla
- carbamazepine
- Carbatrol
- Cerebyx
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- efavirenz
- efavirenz-emtricitabin-tenofov
- Epitol
- Equetro
- fosphenytoin
- Hecoria
- isoniazid-rifamp-pyrazinamide
- nevirapine
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Prograf
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- Sustiva
- tacrolimus
- Tegretol
- Tegretol Xr
- Viramune
- Viramune Xr
- None
Contraindicated
- Disease of liver
Severe
Moderate
- Abnormal hepatic function tests
CANCIDAS (CASPOFUNGIN ACETATE)
- Candida peritonitis
- Candida pleural space infection
- Candidemia
- Esophageal candidiasis
- Febrile neutropenic patient presumed infection treatment
- Intra-abdominal candida abscess
- Refractory aspergillosis
- Abnormal hepatic function tests
- Anemia
- Hypokalemia
- Acute abdominal pain
- Chills
- Diarrhea
- Fever
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- Dyspnea
- Injection site sequelae
- Peripheral edema
- Abdominal distension
- Anorexia
- Body fluid retention
- Constipation
- Cough
- Dizziness
- Drowsy
- Erythema
- Fatigue
- Flushing
- General weakness
- Headache disorder
- Hyperglycemia
- Hypertension
- Hypotension
- Phlebitis after infusion
- Pruritus of skin
- Skin rash
- Stomatitis
- Tachycardia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Anaphylaxis
- Angioedema
- Atrial fibrillation
- Bradycardia
- Bronchospastic pulmonary disease
- Erythema multiforme
- Exfoliative dermatitis
- Hematuria
- Hepatic necrosis
- Hepatitis
- Hyperbilirubinemia
- Hypercalcemia
- Hypomagnesemia
- Hypoxia
- Jaundice
- Kidney disease with reduction in GFR
- Pancreatitis
- Renal failure
- Seizure disorder
- Stevens-johnson syndrome
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
Less Severe
- Acute confusion
- Arthralgias
- Back pain
- Depression
- Dyspepsia
- Epistaxis
- Facial edema
- Insomnia
- Petechiae
- Sensation of warmth
- Symptoms of anxiety
- Tremor
- Urinary tract infection
- Urticaria
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Caspofungin
Rare risk of hepatobiliary dysfunction. Increased risk of CNS and multi-organ infection in neonates. Unknown efficacy with meningitis and endocarditis. No safety and efficacy age < 3 months
Rare risk of hepatobiliary dysfunction reported with underlying serious medical conditions. Unknown efficacy in treating meningitis and endocarditis.
- 1 Day – 89 Days
- Rare risk of hepatobiliary dysfunction. Increased risk of CNS and multi-organ infection in neonates. Unknown efficacy with meningitis and endocarditis. No safety and efficacy age < 3 months
- Rare risk of hepatobiliary dysfunction reported with underlying serious medical conditions. Unknown efficacy in treating meningitis and endocarditis.
- 90 Days – 18 Years
- Rare risk of hepatobiliary dysfunction. Increased risk of CNS and multi-organ infection in neonates. Unknown efficacy with meningitis and endocarditis. No safety and efficacy age < 3 months
- Rare risk of hepatobiliary dysfunction reported with underlying serious medical conditions. Unknown efficacy in treating meningitis and endocarditis.
Caspofungin
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Caspofungin
Insufficient human data available
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
Candida peritonitis | |
B37.89 | Other sites of candidiasis |
K65.0 | Generalized (acute) peritonitis |
T85.71 | Infection and inflammatory reaction due to peritoneal dialysis catheter |
T85.71xA | Infection and inflammatory reaction due to peritoneal dialysis catheter, initial encounter |
Candida pleural space infection | |
B37.1 | Pulmonary candidiasis |
J86 | Pyothorax |
J86.0 | Pyothorax with fistula |
J86.9 | Pyothorax without fistula |
Candidemia | |
B37.7 | Candidal sepsis |
Esophageal candidiasis | |
B37.81 | Candidal esophagitis |
Febrile neutropenic patient presumed infection treatment | |
D70.1 | Agranulocytosis secondary to cancer chemotherapy |
D70.2 | Other drug-induced agranulocytosis |
D70.3 | Neutropenia due to infection |
D70.8 | Other neutropenia |
D70.9 | Neutropenia, unspecified |
R50.81 | Fever presenting with conditions classified elsewhere |
Intra-abdominal candida abscess | |
B37.9 | Candidiasis, unspecified |
D73.3 | Abscess of spleen |
K50.014 | Crohn's disease of small intestine with abscess |
K50.114 | Crohn's disease of large intestine with abscess |
K50.814 | Crohn's disease of both small and large intestine with abscess |
K50.914 | Crohn's disease, unspecified, with abscess |
K51.014 | Ulcerative (chronic) pancolitis with abscess |
K51.214 | Ulcerative (chronic) proctitis with abscess |
K51.314 | Ulcerative (chronic) rectosigmoiditis with abscess |
K51.414 | Inflammatory polyps of colon with abscess |
K51.514 | Left sided colitis with abscess |
K51.814 | Other ulcerative colitis with abscess |
K51.914 | Ulcerative colitis, unspecified with abscess |
K57.0 | Diverticulitis of small intestine with perforation and abscess |
K57.00 | Diverticulitis of small intestine with perforation and abscess without bleeding |
K57.01 | Diverticulitis of small intestine with perforation and abscess with bleeding |
K57.2 | Diverticulitis of large intestine with perforation and abscess |
K57.20 | Diverticulitis of large intestine with perforation and abscess without bleeding |
K57.21 | Diverticulitis of large intestine with perforation and abscess with bleeding |
K57.4 | Diverticulitis of both small and large intestine with perforation and abscess |
K57.40 | Diverticulitis of both small and large intestine with perforation and abscess without bleeding |
K57.41 | Diverticulitis of both small and large intestine with perforation and abscess with bleeding |
K57.8 | Diverticulitis of intestine, part unspecified, with perforation and abscess |
K57.80 | Diverticulitis of intestine, part unspecified, with perforation and abscess without bleeding |
K57.81 | Diverticulitis of intestine, part unspecified, with perforation and abscess with bleeding |
K63.0 | Abscess of intestine |
K65.1 | Peritoneal abscess |
K68.1 | Retroperitoneal abscess |
K68.11 | Postprocedural retroperitoneal abscess |
K68.12 | Psoas muscle abscess |
K68.19 | Other retroperitoneal abscess |
K75.0 | Abscess of liver |
N15.1 | Renal and perinephric abscess |
N34.0 | Urethral abscess |
N41.2 | Abscess of prostate |
Refractory aspergillosis | |
B44 | Aspergillosis |
B44.0 | Invasive pulmonary aspergillosis |
B44.1 | Other pulmonary aspergillosis |
B44.2 | Tonsillar aspergillosis |
B44.7 | Disseminated aspergillosis |
B44.89 | Other forms of aspergillosis |
B44.9 | Aspergillosis, unspecified |
0-9 | A-Z |
---|---|
B37.1 | Pulmonary candidiasis |
B37.7 | Candidal sepsis |
B37.81 | Candidal esophagitis |
B37.89 | Other sites of candidiasis |
B37.9 | Candidiasis, unspecified |
B44 | Aspergillosis |
B44.0 | Invasive pulmonary aspergillosis |
B44.1 | Other pulmonary aspergillosis |
B44.2 | Tonsillar aspergillosis |
B44.7 | Disseminated aspergillosis |
B44.89 | Other forms of aspergillosis |
B44.9 | Aspergillosis, unspecified |
D70.1 | Agranulocytosis secondary to cancer chemotherapy |
D70.2 | Other drug-induced agranulocytosis |
D70.3 | Neutropenia due to infection |
D70.8 | Other neutropenia |
D70.9 | Neutropenia, unspecified |
D73.3 | Abscess of spleen |
J86 | Pyothorax |
J86.0 | Pyothorax with fistula |
J86.9 | Pyothorax without fistula |
K50.014 | Crohn's disease of small intestine with abscess |
K50.114 | Crohn's disease of large intestine with abscess |
K50.814 | Crohn's disease of both small and large intestine with abscess |
K50.914 | Crohn's disease, unspecified, with abscess |
K51.014 | Ulcerative (chronic) pancolitis with abscess |
K51.214 | Ulcerative (chronic) proctitis with abscess |
K51.314 | Ulcerative (chronic) rectosigmoiditis with abscess |
K51.414 | Inflammatory polyps of colon with abscess |
K51.514 | Left sided colitis with abscess |
K51.814 | Other ulcerative colitis with abscess |
K51.914 | Ulcerative colitis, unspecified with abscess |
K57.0 | Diverticulitis of small intestine with perforation and abscess |
K57.00 | Diverticulitis of small intestine with perforation and abscess without bleeding |
K57.01 | Diverticulitis of small intestine with perforation and abscess with bleeding |
K57.2 | Diverticulitis of large intestine with perforation and abscess |
K57.20 | Diverticulitis of large intestine with perforation and abscess without bleeding |
K57.21 | Diverticulitis of large intestine with perforation and abscess with bleeding |
K57.4 | Diverticulitis of both small and large intestine with perforation and abscess |
K57.40 | Diverticulitis of both small and large intestine with perforation and abscess without bleeding |
K57.41 | Diverticulitis of both small and large intestine with perforation and abscess with bleeding |
K57.8 | Diverticulitis of intestine, part unspecified, with perforation and abscess |
K57.80 | Diverticulitis of intestine, part unspecified, with perforation and abscess without bleeding |
K57.81 | Diverticulitis of intestine, part unspecified, with perforation and abscess with bleeding |
K63.0 | Abscess of intestine |
K65.0 | Generalized (acute) peritonitis |
K65.1 | Peritoneal abscess |
K68.1 | Retroperitoneal abscess |
K68.11 | Postprocedural retroperitoneal abscess |
K68.12 | Psoas muscle abscess |
K68.19 | Other retroperitoneal abscess |
K75.0 | Abscess of liver |
N15.1 | Renal and perinephric abscess |
N34.0 | Urethral abscess |
N41.2 | Abscess of prostate |
R50.81 | Fever presenting with conditions classified elsewhere |
T85.71 | Infection and inflammatory reaction due to peritoneal dialysis catheter |
T85.71xA | Infection and inflammatory reaction due to peritoneal dialysis catheter, initial encounter |