TYLENOL COLD-FLU MULTI-ACT D-N (dextromethorphan/pseudoephedrine/acetaminophen/chlorpheniram)

Contraindicated



• Azilect
• Eldepryl
• isocarboxazid
• linezolid
• Marplan
• Matulane
• methylene blue (antidote)
• Nardil
• Parnate
• phenelzine
• procarbazine
• rasagiline
• selegiline HCl
• tranylcypromine
• Zelapar
• Zyvox

Severe



• bromocriptine
• cabergoline
• Cafergot
• Cycloset
• D.h.e.45
• dihydroergotamine
• ergoloid
• Ergomar
• ergotamine tartrate
• ergotamine-caffeine
• K-tab
• Klor-con
• Klor-con 10
• Klor-con M10
• Klor-con M15
• Klor-con M20
• Medi-lyte
• methylergonovine
• Migergot
• Migranal
• Parlodel
• potassium chloride
• potassium citrate
• potassium Cl-calcium phos-mag
• sodium Cl-potassium chloride
• Thermotabs
• Urocit-k 10
• Urocit-k 15
• Urocit-k 5

Contraindicated



• Acetaminophen overdose
• Acute hepatic failure
• Acute hepatitis C
• Severe coronary artery disease
• Severe uncontrolled hypertension
• Urinary retention

Severe



• Angle-closure glaucoma
• Benign prostatic hyperplasia
• Bladder outflow obstruction
• Chronic idiopathic constipation
• Diabetes mellitus
• Disease of liver
• Gastrointestinal obstruction
• Hypertension
• Hyperthyroidism
• Protein-calorie malnutrition
• Shock
• Stenosing peptic ulcer
• Systemic mastocytosis
• Urinary retention

Contraindicated

Chlorpheniramine (Ext. Release)

Not recommended in children under 12 years unless clinician consultation.

Possible paradoxical CNS excitation. Seizure risk in newborns.

Do not use in pediatrics <6 years of age unless clinician consultation.

High risk of adverse CNS effects. Not recommended for use age < 6 years.

• 2 Years – 12 Years
• 1 Not recommended in children under 12 years unless clinician consultation.
• 1 Day – 2 Years
• 1 Not recommended in children under 12 years unless clinician consultation.
• 1 Day – 6 Years
• 1 Not recommended in children under 12 years unless clinician consultation.

Chlorpheniramine (Oral)

Not recommended in children under 12 years unless clinician consultation.

Possible paradoxical CNS excitation. Seizure risk in newborns.

Do not use in pediatrics <6 years of age unless clinician consultation.

High risk of adverse CNS effects. Not recommended for use age < 6 years.

• 2 Years – 12 Years
• 1 Possible paradoxical CNS excitation. Seizure risk in newborns.
• 1 Day – 2 Years
• 1 Possible paradoxical CNS excitation. Seizure risk in newborns.
• 1 Day – 6 Years
• 1 Possible paradoxical CNS excitation. Seizure risk in newborns.

Dextromethorphan (OTC, Select)

Not recommended in children under 12 years unless clinician consultation.

Possible paradoxical CNS excitation. Seizure risk in newborns.

Do not use in pediatrics <6 years of age unless clinician consultation.

High risk of adverse CNS effects. Not recommended for use age < 6 years.

• 2 Years – 12 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 1 Day – 2 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 1 Day – 6 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.

Pseudoephedrine (Immed. Release)

Not recommended in children under 12 years unless clinician consultation.

Possible paradoxical CNS excitation. Seizure risk in newborns.

Do not use in pediatrics <6 years of age unless clinician consultation.

High risk of adverse CNS effects. Not recommended for use age < 6 years.

• 2 Years – 12 Years
• 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.
• 1 Day – 2 Years
• 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.
• 1 Day – 6 Years
• 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.

Severe Precaution

None

Management or Monitoring Precaution

Acetaminophen (oral,rectal)

Use weight based dosing in children less than 12 years.

• 1 Day – 12 Years
• Use weight based dosing in children less than 12 years.