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URIMAR-T (METHENAMINE/METHYLENE BLUE/SALICYLATE/SODIUM PHOS/HYOSCY)
120 mg-0.12 mg-10.8 mg tablet
- Dosage information is not available
81.6 mg-10.8 mg-40.8 mg tablet
- Dosage information is not available
- acetazolamide
- acetazolamide sodium
- Azulfidine
- Azulfidine En-tabs
- Bactrim
- Bactrim Ds
- Diamox Sequels
- erythromycin-sulfisoxazole
- ketorolac
- methazolamide
- Neptazane
- pramlintide
- Sprix
- sulfadiazine
- sulfamethoxazole-trimethoprim
- sulfasalazine
- Sulfatrim
- Sulfazine
- Sulfazine Ec
- Symlinpen 120
- Symlinpen 60
Contraindicated
- Coumadin
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- Jantoven
- K-tab
- Klor-con
- Klor-con 10
- Klor-con M10
- Klor-con M15
- Klor-con M20
- Medi-lyte
- Methotrexate (anti-rheumatic)
- methotrexate sodium
- methotrexate sodium (PF)
- potassium chloride
- potassium citrate
- potassium Cl-calcium phos-mag
- Rheumatrex
- sodium Cl-potassium chloride
- Thermotabs
- Trexall
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
- varicella virus vacc live (PF)
- Varivax (pf)
- warfarin
Severe
Moderate
- A-hydrocort
- A-methapred
- Adasuve
- Amaryl
- Anucort-hc
- Anusol-hc
- Aristospan Intra-articular
- Aristospan Intralesional
- Arixtra
- betamethasone acet & sod phos
- budesonide
- Celestone Soluspan
- chlorpromazine
- colchicine-probenecid
- Colocort
- Compazine
- Compro
- Cortef
- Cortenema
- Cortifoam
- cortisone
- dalteparin (porcine)
- Depacon
- Depakene
- Depakote
- Depakote Er
- Depakote Sprinkles
- Depo-medrol
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Diabeta
- divalproex
- Duetact
- Elmiron
- enoxaparin
- Entocort Ec
- Ez Use Joint-tunnel-trigger
- First-duke's
- First-mary's Mouthwash
- Flo-pred
- fludrocortisone
- fluphenazine decanoate
- fluphenazine HCl
- fondaparinux
- Fragmin
- glimepiride
- glipizide
- glipizide-metformin
- Glucotrol
- Glucotrol Xl
- Glucovance
- glyburide
- glyburide micronized
- glyburide-metformin
- Glynase
- Grx Hicort 25
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- Hemril-30
- heparin (porcine)
- heparin (porcine) in D5W
- heparin(porcine) in 0.45% NaCl
- heparin, porcine (PF)
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- itraconazole
- Kenalog
- ketoconazole
- Lovenox
- loxapine
- loxapine succinate
- Loxitane
- Medrol
- Medrol (pak)
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- Millipred
- Millipred Dp
- nateglinide
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Onmel
- Orapred
- Orapred Odt
- Pediapred
- pentosan polysulfate sodium
- perphenazine
- perphenazine-amitriptyline
- Phenadoz
- Phenergan
- Physicians Ez Use M-pred
- pioglitazone-glimepiride
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- probenecid
- prochlorperazine
- prochlorperazine Edisylate
- prochlorperazine maleate
- Proctocort
- promethazine
- Promethazine Vc
- Promethazine Vc-codeine
- promethazine-codeine
- promethazine-DM
- promethazine-phenyleph-codeine
- promethazine-phenylephrine
- Promethegan
- Rayos
- Rectacort-hc
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Sporanox
- Sporanox Pulsepak
- Starlix
- Stavzor
- thioridazine
- tolazamide
- tolbutamide
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- trifluoperazine
- Uceris
- valproate sodium
- valproic acid
- valproic acid (as sodium salt)
- Veripred 20
- Achalasia of esophagus
- Aspirin exacerbated respiratory disease
- Atony of colon
- Benign prostatic hyperplasia
- Bladder outflow obstruction
- Gastrointestinal hemorrhage
- Glaucoma
- Glucose-6-phosphate dehydrogenase (g6Pd) deficiency
- Hemolytic anemia from PK and g6PD deficiencies
- Hemophilia
- Hypernatremia
- Hyperphosphatemia
- Hypocalcemia
- Hypovolemic shock
- Increased risk of bleeding due to coagulation disorder
- Lactating mother
- Myasthenia gravis
- Paralytic ileus
- Pregnancy
- Pyloroduodenal obstruction
- Severe dehydration
- Severe hepatic disease
- Severe renal impairment
- Severe ulcerative colitis
- Toxic megacolon
Contraindicated
- Chronic heart failure
- Edema
- Gastritis
- Gastroesophageal reflux disease
- Gastrointestinal ulcer
- Hypoprothrombinemia
- Increased cardiovascular event risk
- Increased risk of bleeding
- Kidney disease with reduction in GFR
- Nasal polyp
- Pregnancy
- Severe hepatic disease
- Severe renal impairment
- Thrombotic thrombocytopenic purpura
- Vitamin K deficiency
Severe
Moderate
- Abnormal hepatic function tests
- Anemia
- Autonomic neuropathy
- Cardiac arrhythmia
- Chronic heart failure
- Coronary artery disease
- Diabetes mellitus
- Disease of liver
- Edema
- Gastroesophageal reflux disease
- Hepatic cirrhosis
- Hiatal hernia
- High fever >101 degrees fahrenheit
- Hypertension
- Hyperthyroidism
- Kidney disease with reduction in GFR
- Severe hepatic disease
- Thyrotoxicosis
URIMAR-T (METHENAMINE/METHYLENE BLUE/SALICYLATE/SODIUM PHOS/HYOSCY)
- None
- Blurred vision
- Decreased sweating
- Urine discoloration
More Frequent
Severe
Less Severe
- Skin rash
- Abdominal pain with cramps
- Breast milk flow decreased
- Constipation
- Diarrhea
- Dyspepsia
- Gastric acid hypersecretory conditions
- Gastrointestinal irritation
- Heartburn
- Increased urinary frequency
- Mydriasis
- Nausea
- Nausea and vomiting
- Vomiting
- Xerostomia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute confusion
- Allergic dermatitis
- Anaphylaxis
- Anemia
- Angioedema
- Bronchospastic pulmonary disease
- Cardiac arrhythmia
- Dyspnea
- Erythema
- Gastrointestinal hemorrhage
- Gastrointestinal perforation
- Gastrointestinal ulcer
- Hematuria
- Hemolytic anemia
- Hypernatremia
- Hyperphosphatemia
- Hypocalcemia
- Nephrocalcinosis
- Ocular hypertension
- Oliguria
- Orthostatic hypotension
- Pruritus of skin
- Renal failure
- Seizure disorder
- Skin rash
- Urticaria
- Wheezing
Less Severe
- Acute abdominal pain
- Acute confusion
- Arthralgias
- Bone pain
- Cramps
- Dizziness
- Drowsy
- Dysuria
- Fatigue
- Fever
- Flatulence
- General weakness
- Headache disorder
- Memory impairment
- Nausea
- Oral paresthesia
- Paresthesia
- Peripheral edema
- Polydipsia
- Pruritus of skin
- Vomiting
- Weight gain
Contraindicated
Salicylates
Do not use in viral illness due to possible increased risk of Reye syndrome.
- 1 Day – 12 Years
- 1 Do not use in viral illness due to possible increased risk of Reye syndrome.
Severe Precaution
Hyoscyamine
Infants and children are more sensitive to anticholinergic and adverse effects.
Do not use in viral illness due to possible increased risk of Reye syndrome.
- 1 Day – 13 Years
- Infants and children are more sensitive to anticholinergic and adverse effects.
- 12 Years – 18 Years
- Infants and children are more sensitive to anticholinergic and adverse effects.
Salicylates
Infants and children are more sensitive to anticholinergic and adverse effects.
Do not use in viral illness due to possible increased risk of Reye syndrome.
- 1 Day – 13 Years
- Do not use in viral illness due to possible increased risk of Reye syndrome.
- 12 Years – 18 Years
- Do not use in viral illness due to possible increased risk of Reye syndrome.
Management or Monitoring Precaution
None
Hyoscyamine
- Severity Level:
C
- Additional Notes:
Methenamine
- Severity Level:
C
- Additional Notes:
Methylene Blue
- Severity Level:
D
- Additional Notes: Serious fetal/neonatal adverse effects with intra-amniotic admin
Salicylates
- Severity Level:
1
- Additional Notes: Salicylates not recommended especially in 3rd trimester/near term
Contraindicated
Salicylates
One report of metabol acidosis w/asa;Risk of reye's syn w/viral illness/fever
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Excreted | Not known; no or inclusive data | One report of metabol acidosis w/asa;Risk of reye's syn w/viral illness/fever |
Precaution Exists
Hyoscyamine
Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics
Insufficient data available
Insufficient data available; should not be used if infant has g6Pd deficiency
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics |
Methenamine
Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics
Insufficient data available
Insufficient data available; should not be used if infant has g6Pd deficiency
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Insufficient data available |
Methylene Blue
Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics
Insufficient data available
Insufficient data available; should not be used if infant has g6Pd deficiency
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available; should not be used if infant has g6Pd deficiency |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Hyoscyamine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-Avoid with gastrointestinal ileus. May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
General-Elderly have a higher incidence of systemic toxicities. Dose reduction may be needed.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
Phenyl Salicylate (salol)
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-Avoid with gastrointestinal ileus. May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
General-Elderly have a higher incidence of systemic toxicities. Dose reduction may be needed.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
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