URETRON D-S (METHENAMINE/METHYLENE BLUE/SODIUM PHOS/PNYL SAL/HYOSC SUL)

Moderate

• A-hydrocort

• A-methapred

• Adasuve

• Amaryl

• Anucort-hc

• Anusol-hc

• Aristospan Intra-articular

• Aristospan Intralesional

• Arixtra

• betamethasone acet & sod phos

• budesonide

• Celestone Soluspan

• chlorpromazine

• colchicine-probenecid

• Colocort

• Compazine

• Compro

• Cortef

• Cortenema

• Cortifoam

• cortisone

• dalteparin (porcine)

• Depacon

• Depakene

• Depakote

• Depakote Er

• Depakote Sprinkles

• Depo-medrol

• dexamethasone

• Dexamethasone Intensol

• dexamethasone sodium phos (PF)

• dexamethasone sodium phosphate

• Dexpak 10 Day

• Dexpak 13 Day

• Dexpak 6 Day

• Diabeta

• divalproex

• Duetact

• Elmiron

• enoxaparin

• Entocort Ec

• Ez Use Joint-tunnel-trigger

• First-duke's

• First-mary's Mouthwash

• Flo-pred

• fludrocortisone

• fluphenazine decanoate

• fluphenazine HCl

• fondaparinux

• Fragmin

• glimepiride

• glipizide

• glipizide-metformin

• Glucotrol

• Glucotrol Xl

• Glucovance

• glyburide

• glyburide micronized

• glyburide-metformin

• Glynase

• Grx Hicort 25

• Haldol

• Haldol Decanoate

• haloperidol

• haloperidol decanoate

• haloperidol lactate

• Hemril-30

• heparin (porcine)

• heparin (porcine) in D5W

• heparin(porcine) in 0.45% NaCl

• heparin, porcine (PF)

• hydrocortisone

• hydrocortisone acetate

• hydrocortisone sod succ (PF)

• hydrocortisone sod succinate

• itraconazole

• Kenalog

• ketoconazole

• Lovenox

• loxapine

• loxapine succinate

• Loxitane

• Medrol

• Medrol (pak)

• methylprednisolone

• methylprednisolone acetate

• methylprednisolone sod suc(PF)

• methylprednisolone sodium succ

• methylprednisolone-bupivacaine

• Millipred

• Millipred Dp

• nateglinide

• nystatin-hydrocortisone-diphen

• nystatin-TCN-HC-diphenhydramin

• Onmel

• Orapred

• Orapred Odt

• Pediapred

• pentosan polysulfate sodium

• perphenazine

• perphenazine-amitriptyline

• Phenadoz

• Phenergan

• Physicians Ez Use M-pred

• pioglitazone-glimepiride

• prednisolone

• prednisolone acetate

• prednisolone sodium phosphate

• prednisone

• Prednisone Intensol

• probenecid

• prochlorperazine

• prochlorperazine Edisylate

• prochlorperazine maleate

• Proctocort

• promethazine

• Promethazine Vc

• Promethazine Vc-codeine

• promethazine-codeine

• promethazine-DM

• promethazine-phenyleph-codeine

• promethazine-phenylephrine

• Promethegan

• Rayos

• Rectacort-hc

• Solu-cortef

• Solu-cortef (pf)

• Solu-medrol

• Solu-medrol (pf)

• Sporanox

• Sporanox Pulsepak

• Starlix

• Stavzor

• thioridazine

• tolazamide

• tolbutamide

• triamcinolone acetonide

• triamcinolone hexacetonide

• triamcinolone-lidocaine

• trifluoperazine

• Uceris

• valproate sodium

• valproic acid

• valproic acid (as sodium salt)

• Veripred 20

Moderate

• Abnormal hepatic function tests

• Anemia

• Autonomic neuropathy

• Cardiac arrhythmia

• Chronic heart failure

• Coronary artery disease

• Diabetes mellitus

• Disease of liver

• Edema

• Gastroesophageal reflux disease

• Hepatic cirrhosis

• Hiatal hernia

• High fever >101 degrees fahrenheit

• Hypertension

• Hyperthyroidism

• Kidney disease with reduction in GFR

• Severe hepatic disease

• Thyrotoxicosis

Hyoscyamine

• Severity Level:

  C

• Additional Notes:

Methenamine

• Severity Level:

  C

• Additional Notes:

Methylene Blue

• Severity Level:

  D

• Additional Notes: Serious fetal/neonatal adverse effects with intra-amniotic admin

Salicylates

• Severity Level:

  1

• Additional Notes: Salicylates not recommended especially in 3rd trimester/near term

Contraindicated

Salicylates

One report of metabol acidosis w/asa;Risk of reye's syn w/viral illness/fever

General	Excretion Potential	Effect on Infant	Notes
Drug should not be given to breast feeding mothers	Excreted	Not known; no or inclusive data	One report of metabol acidosis w/asa;Risk of reye's syn w/viral illness/fever

Precaution Exists

Hyoscyamine

Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics

Insufficient data available

Insufficient data available; should not be used if infant has g6Pd deficiency

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics

Methenamine

Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics

Insufficient data available

Insufficient data available; should not be used if infant has g6Pd deficiency

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Insufficient data available

Methylene Blue

Trace amt excreted,not recom per mfr;Neonates sensitive to antichlolinergics

Insufficient data available

Insufficient data available; should not be used if infant has g6Pd deficiency

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Unknown	Not known; no or inclusive data	Insufficient data available; should not be used if infant has g6Pd deficiency

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Hyoscyamine

Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-Avoid with gastrointestinal ileus. May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.

General-Elderly have a higher incidence of systemic toxicities. Dose reduction may be needed.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	N	Y	N	N

BEERS: Y     HEDIS: Y     STOPP: Y

Phenyl Salicylate (salol)

Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-Avoid with gastrointestinal ileus. May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.

General-Elderly have a higher incidence of systemic toxicities. Dose reduction may be needed.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	N	Y	N	N

BEERS: N     HEDIS: N     STOPP: N

No Known Risk

None

0-9	A-Z