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TRANDOLAPRIL (TRANDOLAPRIL)
- Chronic heart failure
- Hypertension
- Left ventricular dysfunction following MI
1 mg tablet
- 1 tablet (1 mg) by oral route once daily
2 mg tablet
- 1 tablet (2 mg) by oral route once daily
4 mg tablet
- 1 tablet (4 mg) by oral route once daily
Chronic heart failure
- 1 tablet (1 mg) by oral route once daily
- 2 tablets (2 mg) by oral route once daily
- 1 tablet (2 mg) by oral route once daily
- 2 tablets (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route once daily
Hypertension
- 1 tablet (1 mg) by oral route once daily
- 2 tablets (2 mg) by oral route once daily
- 1 tablet (2 mg) by oral route once daily
- 2 tablets (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route 2 times per day
- 2 tablets (4 mg) by oral route 2 times per day
- 2 tablets (8 mg) by oral route once daily
- None
Contraindicated
- aliskiren
- aliskiren-amlodipin-hcthiazide
- aliskiren-amlodipine
- aliskiren-hydrochlorothiazide
- Amturnide
- Curad Enema
- Disposable Enema
- Enema
- Enema Disposable
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- lithium carbonate
- lithium citrate
- Lithobid
- Oral Saline Laxative
- Osmoprep
- Phosphate Laxative
- Preparation Cleansing
- Ready-to-use Enema
- sod phos mono-sod phos dibasic
- sodium phosphates
- Tekamlo
- Tekturna
- Tekturna Hct
Severe
Moderate
- Added Strength Headache Relief
- Added Strength Pain Reliever
- Alka-seltzer
- Alka-seltzer Extra Strength
- Alka-seltzer Original
- Alka-seltzer Plus C/c(pe,dm)
- Alka-seltzer Plus Cold (pe)
- Alka-seltzer Plus Day-night
- Alka-seltzer Plus Night
- Alka-seltzer Pm
- Anacin
- Anacin Maximum Strength
- Analgesic
- Angeliq
- Antacid & Pain Relief
- ASA-acetaminophen-caff-buffers
- ASA-acetaminophen-salicyl-caff
- Ascomp With Codeine
- Aspir-trin
- aspirin
- aspirin, buffered
- aspirin-acetaminophen-caffeine
- aspirin-caffeine
- aspirin-diphenhydramine
- aspirin-diphenhydramine citrat
- aspirin-sod bicarb-citric acid
- Azasan
- azathioprine
- azathioprine sodium
- Back & Body Pain Reliever
- Bactrim
- Bactrim Ds
- Bayer Advanced
- Bayer Aspirin
- Bayer Aspirin (with Caffeine)
- Bayer Back & Body
- Bayer Plus Extra Strength
- Bayer Pm
- Bc
- Bc Arthritis
- Beyaz
- Buffered Aspirin
- Bufferin
- bumetanide
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-aspirin-caffeine
- carisoprodol-ASA-codeine
- carisoprodol-aspirin
- chlorphen-phenyleph-DM-aspirin
- chlorphenir-phenylephrn-aspirn
- codeine-butalbital-ASA-caff
- Cold Relief
- Cold Relief Plus
- Demadex
- dihydrocodeine-aspirin-caff
- doxylamine-phenylep-DM-aspirin
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- E.c. Prin
- Ecotrin
- Efferves Pain Relief Antacid
- Effervescent Antacid
- Effervescent Pain Relief
- Effervescent Pain Reliever
- Endodan
- ethacrynate sodium
- Excedrin Extra Strength
- Excedrin Migraine
- Extra Strength Bayer
- Fiorinal
- Fiorinal-codeine #3
- furosemide
- Gianvi (28)
- Goody's Extra Strength
- Goody's Migraine Relief
- Headache Formula
- Headache Formula Added Str
- Headache Relief
- Imuran
- Lasix
- Levacet
- Lite Coat Aspirin
- Loryna (28)
- Medi-seltzer
- mercaptopurine
- Migraine Formula
- Migraine Pain Reliever
- Migraine Relief
- Ocella
- Orphenadrine Compound Forte
- Orphenadrine Compound-ds
- orphenadrine-ASA-caffeine
- oxycodone-aspirin
- Pain Relief
- Pain Relief Extra Strength
- Pain Reliever
- Pain Reliever Extra Strength
- Pain Reliever Plus
- Pain-off
- Pamprin Max
- PE-DM-ASA/doxyla-PE-DM-ASA
- Percodan
- Primsol
- Purinethol
- Safyral
- Sodium Edecrin
- sulfamethoxazole-trimethoprim
- Sulfatrim
- Super Pain Relief
- Syeda
- Synalgos-dc
- torsemide
- Tri-buffered Aspirin
- trimethoprim
- Vanquish
- Vestura (28)
- Yasmin (28)
- Yaz 28
- Zarah
- Pregnancy
Contraindicated
- Angioedema
- Dehydration
- Disease of liver
- Hemodialysis with high-flux membrane
- Hyperkalemia
- Hyponatremia
- Hypotension
Severe
Moderate
- Agranulocytosis
- Bone marrow depression
- Kidney disease with reduction in GFR
- Neutropenic disorder
- Renal artery stenosis
TRANDOLAPRIL (TRANDOLAPRIL)
- Chronic heart failure
- Hypertension
- Left ventricular dysfunction following MI
- None
- None
More Frequent
Severe
Less Severe
- Dizziness
- Cough
- Diarrhea
- Dyspepsia
- General weakness
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Acute renal failure
- Agranulocytosis
- Anaphylaxis
- Angioedema
- Atrioventricular block
- Bradycardia
- Cardiac arrhythmia
- Dyspnea
- Eosinophilic pneumonia
- Gout
- Head and neck angioedema
- Hepatic necrosis
- Hepatitis
- Hyperkalemia
- Hypocalcemia
- Hyponatremia
- Hypotension
- Intermittent claudication
- Intestinal angioedema
- Intracerebral hemorrhage
- Jaundice
- Laryngeal edema
- Leukopenia
- Neutropenic disorder
- Obstructive hyperbilirubinemia
- Pancreatitis
- Pemphigus
- Stevens-johnson syndrome
- Syncope
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Transient cerebral ischemia
Less Severe
- Abdominal distension
- Abdominal pain with cramps
- Alopecia
- Bronchitis
- Constipation
- Cramps
- Depression
- Drowsy
- Edema
- Epistaxis
- Erectile dysfunction
- Fever
- Flushing
- Gastritis
- Hallucinations
- Hyperbilirubinemia
- Hyperhidrosis
- Insomnia
- Libido changes
- Limb pain
- Malaise
- Myalgias
- Nausea
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin rash
- Symptoms of anxiety
- Vertigo
- Vomiting
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Trandolapril
Safety and efficacy not established.
- 1 Day – 18 Years
- Safety and efficacy not established.
Trandolapril
- Severity Level:
1
- Additional Notes: Fetal death/morbidity w/use in 2nd & 3rd trimester, stop when pregnancy detected
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Trandolapril
Excreted in rats; insufficient human data available; mfr does not rec
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Excreted in rats; insufficient human data available; mfr does not rec |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Trandolapril
General-Monitor for increased serum creatinine or hyperkalemia. Cardiovascular-Monitor for hypotension.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- Trandolapril can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, tell your doctor right away.
| Chronic heart failure | |
| I50.22 | Chronic systolic (congestive) heart failure |
| I50.32 | Chronic diastolic (congestive) heart failure |
| I50.42 | Chronic combined systolic (congestive) and diastolic (congestive) heart failure |
| I50.812 | Chronic right heart failure |
| I50.814 | Right heart failure due to left heart failure |
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| Left ventricular dysfunction following MI | |
| I23.8 | Other current complications following acute myocardial infarction |
| I50.1 | Left ventricular failure, unspecified |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| I23.8 | Other current complications following acute myocardial infarction |
| I50.1 | Left ventricular failure, unspecified |
| I50.22 | Chronic systolic (congestive) heart failure |
| I50.32 | Chronic diastolic (congestive) heart failure |
| I50.42 | Chronic combined systolic (congestive) and diastolic (congestive) heart failure |
| I50.812 | Chronic right heart failure |
| I50.814 | Right heart failure due to left heart failure |
Formulary Reference Tool