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XENAZINE (TETRABENAZINE)
- Chorea associated with huntington's disease
12.5 mg tablet
- 1 tablet (12.5 mg) by oral route 3 times per day
25 mg tablet
- 1 tablet (25 mg) by oral route 2 times per day
12.5 mg tablet
- 1 tablet (12.5 mg) by oral route 3 times per day
25 mg tablet
- 1 tablet (25 mg) by oral route 2 times per day
Chorea associated with huntington's disease
- 1 tablet (25 mg) by oral route 2 times per day
- 1 tablet (25 mg) by oral route 3 times per day
- 2 tablets (25 mg) by oral route 3 times per day
- 2 tablets (25 mg) by oral route 2 times per day
- 1 tablet (12.5 mg) by oral route 3 times per day
- 1 tablet (12.5 mg) by oral route 2 times per day
- Azilect
- carbidopa-levodopa
- carbidopa-levodopa-entacapone
- Eldepryl
- isocarboxazid
- linezolid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- rasagiline
- reserpine
- selegiline HCl
- Sinemet
- Sinemet Cr
- Stalevo 100
- Stalevo 125
- Stalevo 150
- Stalevo 200
- Stalevo 50
- Stalevo 75
- tranylcypromine
- Zelapar
- Zyvox
Contraindicated
- amiodarone
- amiodarone in dextrose,iso-osm
- Apokyn
- apomorphine
- arsenic trioxide
- artemether-lumefantrine
- bedaquiline
- Betapace
- Betapace Af
- Celexa
- chloroquine phosphate
- chlorpromazine
- citalopram
- Coartem
- Cordarone
- Corvert
- dasatinib
- Diskets
- disopyramide
- dofetilide
- Dolophine
- dronedarone
- droperidol
- escitalopram oxalate
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- ibutilide fumarate
- Invega
- Invega Sustenna
- isradipine
- Lexapro
- methadone
- Methadone Intensol
- Methadose
- Multaq
- Nebupent
- Nexterone
- nilotinib
- norfloxacin
- Noroxin
- Norpace
- Norpace Cr
- Orap
- Pacerone
- paliperidone
- paliperidone palmitate
- pasireotide
- Pentam
- pentamidine
- pimozide
- procainamide
- propafenone
- Qualaquin
- quinine sulfate
- Rythmol
- Signifor
- Sirturo
- Sorine
- sotalol
- Sotalol Af
- Sprycel
- Tasigna
- thioridazine
- Tikosyn
- Trisenox
Severe
Moderate
- Ablavar
- Advair Diskus
- Advair Hfa
- alfuzosin
- Aloxi
- amantadine HCl
- Anzemet
- arformoterol
- Astagraf Xl
- Avelox
- Avelox Abc Pack
- Avelox In Nacl (iso-osmotic)
- Brisdelle
- Brovana
- budesonide-formoterol
- Caprelsa
- Cardene Iv
- Cardene Iv In Dextrose
- Cardene Iv In Sodium Chloride
- Cardene Sr
- clozapine
- Clozaril
- Complera
- crizotinib
- dextromethorphan-quinidine
- dolasetron
- Dulera
- Edurant
- Effexor Xr
- emtricitab-rilpivirine-tenofov
- Eovist
- eribulin
- ezogabine
- Fareston
- Fazaclo
- felbamate
- Felbatol
- flecainide
- fluoxetine
- fluticasone-salmeterol
- Foradil Aerolizer
- formoterol fumarate
- foscarnet
- Foscavir
- gadofosveset trisodium
- gadoxetate
- Geodon
- granisetron
- granisetron (PF)
- Granisol
- Halaven
- Hecoria
- indapamide
- Invirase
- Istodax
- Kaletra
- Ketek
- Lamisil
- lapatinib
- Levaquin
- Levaquin In 5 % Dextrose
- Levitra
- levofloxacin
- levofloxacin in D5W
- lithium carbonate
- lithium citrate
- Lithobid
- lopinavir-ritonavir
- moexipril
- moexipril-hydrochlorothiazide
- mometasone-formoterol
- moxifloxacin
- moxifloxacin in NaCl (iso-osm)
- Nexavar
- nicardipine
- nicardipine in dextrose,iso-os
- nicardipine in NaCl (iso-os)
- Noxafil
- Nuedexta
- octreotide acetate
- ofloxacin
- olanzapine-fluoxetine
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- palonosetron
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- pazopanib
- Perforomist
- Pexeva
- posaconazole
- Potiga
- Prograf
- Prozac
- Prozac Weekly
- quetiapine
- quinidine gluconate
- quinidine sulfate
- rilpivirine
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- romidepsin
- salmeterol
- Sancuso
- Sandostatin
- Sandostatin Lar Depot
- saquinavir mesylate
- Sarafem
- Serevent Diskus
- Seroquel
- Seroquel Xr
- Soltamox
- sorafenib
- sunitinib
- Sutent
- Symbicort
- Symbyax
- tacrolimus
- tamoxifen
- telavancin
- telithromycin
- terbinafine
- tizanidine
- toremifene
- Tykerb
- Uniretic
- Univasc
- Uroxatral
- vandetanib
- vardenafil
- vemurafenib
- venlafaxine
- Versacloz
- Vfend
- Vfend Iv
- Vibativ
- voriconazole
- Votrient
- Xalkori
- Zanaflex
- Zelboraf
- ziprasidone HCl
- ziprasidone mesylate
- Zofran
- Zofran Odt
- Zuplenz
- Congenital long QT syndrome
- Disease of liver
- Neuroleptic malignant syndrome
Contraindicated
- Akathisia
- CYp2d6 poor metabolizer
- Depression
- Parkinsonism
- Prolonged QT interval
- Suicidal ideation
- Torsades de pointes
Severe
Moderate
- Dysphagia
- Hyperprolactinemia
- Hypotension
- Orthostatic hypotension
XENAZINE (TETRABENAZINE)
- Chorea associated with huntington's disease
- Akathisia
- Extrapyramidal disease
- Parkinsonism
- Depression
- Drowsy
- Fatigue
- Insomnia
- Nausea
- Sedation
- Symptoms of anxiety
More Frequent
Severe
Less Severe
- Agitation
- Dyspnea
- Anorexia
- Bronchitis
- Dizziness
- Dysarthria
- Dysphagia
- Dysuria
- Ecchymosis
- Headache disorder
- Irritability
- Nervousness
- Orthostatic hypotension
- Unsteady gait
- Upper respiratory infection
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Neuroleptic malignant syndrome
- Pneumonia
- Prolonged QT interval
- Suicidal ideation
Less Severe
- Acute confusion
- Aggressive behavior
- Hyperhidrosis
- Hyperprolactinemia
- Skin rash
- Tremor
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Deutetra-and tetrabenazine
No safety and efficacy established.
- 1 Day – 18 Years
- No safety and efficacy established.
Tetrabenazine
- Severity Level:
2
- Additional Notes: Insufficient human data
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Tetrabenazine
Insufficient human data
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Tetrabenazine can sometimes increase the risk of depression and suicidal thoughts/attempts. People with Huntington's disease are more likely to have depression and suicidal thoughts/attempts. Discuss the risks and benefits of this medication with your doctor.<br /><br />People who are not being treated for their depression and suicidal thoughts/attempts, or people who have persistent symptoms of these conditions (even with medication/treatment) must not use tetrabenazine. Tell your doctor right away if you or your family/caregivers notice that you have new/worsening symptoms of depression, sadness, loss of interest in activities you used to enjoy, suicidal thoughts/attempts, or other mental/mood/behavior changes (such as new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, strong/abnormal urges, severe restlessness, very rapid speech).
| Chorea associated with huntington's disease | |
| G10 | Huntington's disease |
| 0-9 | A-Z |
|---|---|
| G10 | Huntington's disease |
Formulary Reference Tool