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ORASEP (BENZOCAINE/MENTHOL/CETYLPYRIDINIUM CHLORIDE)
- Mouth irritation
- Aphthous stomatitis
- Denture stomatitis
- Gingivostomatitis
- Sore throat
2 %-0.5 %-0.1 % mucosal spray
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- None
- Methemoglobinemia
Contraindicated
- Glucose-6-phosphate dehydrogenase (g6Pd) deficiency
- Hemolytic anemia from PK and g6PD deficiencies
- NADH methemoglobin reductase deficiency
- Systemic mastocytosis
Severe
Moderate
- None
ORASEP (BENZOCAINE/MENTHOL/CETYLPYRIDINIUM CHLORIDE)
- Mouth irritation
- Aphthous stomatitis
- Denture stomatitis
- Gingivostomatitis
- Sore throat
- None
- None
More Frequent
Severe
Less Severe
- Angioedema
- Contact dermatitis
- Erythema
- Mouth irritation
- Pruritus of skin
- Skin rash
- Urticaria
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Methemoglobinemia
Less Severe
- None
Contraindicated
Benzocaine (Oral,muc memb)
Increased risk for developing methemoglobinemia. Avoid use in infant or child age < 2 years.
- 1 Day – 2 Years
- 1 Increased risk for developing methemoglobinemia. Avoid use in infant or child age < 2 years.
Severe Precaution
Benzocaine (Oral,muc memb)
Increased risk for developing methemoglobinemia. Consult clinician prior to use.
- 2 Years – 6 Years
- Increased risk for developing methemoglobinemia. Consult clinician prior to use.
Management or Monitoring Precaution
None
Benzocaine(systemic)
- Severity Level:
D
- Additional Notes: Briggs does not recommend use on mucous membranes
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Benzocaine
Reports of infant methemoglobinemia after ingestion of topical benzocaine
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | No adverse effect | Reports of infant methemoglobinemia after ingestion of topical benzocaine |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Select Anesthetics
General-May be more sensitive to CNS and cardiac adverse reactions. Consider dose reduction due to reduced clearance in the elderly.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Aphthous stomatitis | |
| K12.0 | Recurrent oral aphthae |
| Denture stomatitis | |
| K12.1 | Other forms of stomatitis |
| Gingivostomatitis | |
| K05.10 | Chronic gingivitis, plaque induced |
| Mouth irritation | |
| K13.79 | Other lesions of oral mucosa |
| Sore throat | |
| R07.0 | Pain in throat |
| 0-9 | A-Z |
|---|---|
| K05.10 | Chronic gingivitis, plaque induced |
| K12.0 | Recurrent oral aphthae |
| K12.1 | Other forms of stomatitis |
| K13.79 | Other lesions of oral mucosa |
| R07.0 | Pain in throat |
Formulary Reference Tool