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QUADRAMET (SAMARIUM SM 153 LEXIDRONAM)
- Pain due to osteoblastic bone metastasis
5,550 MBq/3 mL intravenous solution
- Dosage information is not available
5,550 MBq/3 mL intravenous solution
- Dosage information is not available
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- BCG vaccine, live (PF)
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- typhoid vaccine
- Tysabri
- varicella virus vacc live (PF)
- Varivax (pf)
- Vivotif Berna Vaccine
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- clozapine
- Clozaril
- deferiprone
- Fazaclo
- Ferriprox
- Versacloz
Severe
Moderate
- None
- Lactating mother
- Pregnancy
Contraindicated
- Bone marrow depression
- Neutropenic disorder
- Secondary malignant neoplasm of bone marrow
- Thrombocytopenic disorder
Severe
Moderate
- Chronic heart failure
- Kidney disease with likely reduction in GFR
- Kidney disease with reduction in GFR
QUADRAMET (SAMARIUM SM 153 LEXIDRONAM)
- Pain due to osteoblastic bone metastasis
- Bone marrow depression
- Leukopenia
- Thrombocytopenic disorder
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- Cardiac arrhythmia
- Epistaxis
- Hematuria
- Hypertension
- Hypotension
- Increased risk of bleeding due to coagulation disorder
- Infection
- Lymphadenopathy
- Spinal cord compression
- Acute abdominal pain
- Chills
- Cough
- Diarrhea
- Dizziness
- Ecchymosis
- Fever
- Muscle weakness
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Chest pain
- Chronic heart failure
- Purpura
Less Severe
- Alopecia
- Angina
- Flare reaction bone pain
- Vasodilation of blood vessels
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Samarium Sm 153 Lexidronam
- Severity Level:
1
- Additional Notes:
Contraindicated
Samarium Sm 153 Lexidronam
Not recommended. potential for serious adverse effects on infant
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Not recommended. potential for serious adverse effects on infant |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Pain due to osteoblastic bone metastasis | |
| C79.51 | Secondary malignant neoplasm of bone |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| 0-9 | A-Z |
|---|---|
| C79.51 | Secondary malignant neoplasm of bone |
| G89.3 | Neoplasm related pain (acute) (chronic) |
Formulary Reference Tool