DAY-NITE SEVERE COLD-FLU (DOXYLAMINE/PHENYLEPHRINE/DEXTROMETHORPHAN/ACETAMINOPHEN/GG)

Contraindicated



• Azilect
• Eldepryl
• isocarboxazid
• linezolid
• Marplan
• Matulane
• methylene blue (antidote)
• Nardil
• Parnate
• phenelzine
• procarbazine
• rasagiline
• selegiline HCl
• tranylcypromine
• Zelapar
• Zyvox

Severe



• bromocriptine
• cabergoline
• Cafergot
• Compound 347
• Cycloset
• D.h.e.45
• dihydroergotamine
• enflurane
• ergoloid
• Ergomar
• ergotamine tartrate
• ergotamine-caffeine
• Forane
• isoflurane
• methylergonovine
• Migergot
• Migranal
• Parlodel
• sevoflurane
• Sojourn
• Terrell
• Ultane

Contraindicated



• Acetaminophen overdose
• Acute hepatic failure
• Acute hepatitis C
• Acute myocardial infarction
• Arterial thrombosis
• Severe uncontrolled hypertension
• Ventricular tachycardia

Severe



• Acute hepatitis
• Acute pancreatitis
• Angle-closure glaucoma
• Benign prostatic hyperplasia
• Bladder outflow obstruction
• Bradycardia
• Chronic idiopathic constipation
• Coronary artery disease
• Disease of liver
• Hypertension
• Hyperthyroidism
• Incomplete AV heart block
• Protein-calorie malnutrition
• Severe arteriosclerotic vascular disease
• Severe renal impairment
• Shock
• Stenosing peptic ulcer
• Systemic mastocytosis
• Urinary retention

Contraindicated

Dextromethorphan (OTC)

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 1 Day – 2 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.

Doxylamine

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.
• 1 Day – 2 Years
• 1 CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Phenylephrine (Oral,Rectal)

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
• 1 Day – 2 Years
• 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.

Severe Precaution

Doxylamine

CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.

• 2 Years – 6 Years
• CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.

Management or Monitoring Precaution

Acetaminophen (oral,rectal)

Use weight based dosing in children less than 12 years.

Consult clinician for use in pediatrics age < 12 years.

• 1 Day – 12 Years
• Use weight based dosing in children less than 12 years.

Guaifenesin (solid dose form)

Use weight based dosing in children less than 12 years.

Consult clinician for use in pediatrics age < 12 years.

• 1 Day – 12 Years
• Consult clinician for use in pediatrics age < 12 years.