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ADRENALIN (EPINEPHRINE)
- Allergic reaction
- Anaphylaxis
- Mydriasis during ocular surgery
- Septic shock
1 mg/mL (1 mL) injection solution
- Dosage information is not available
1 mg/mL injection solution
- Dosage information is not available
1 mg/mL (1 mL) injection solution
- Dosage information is not available
1 mg/mL injection solution
- Dosage information is not available
- None
Contraindicated
- acebutolol
- atenolol
- atenolol-chlorthalidone
- betaxolol
- Betimol
- brimonidine-timolol
- bromocriptine
- cabergoline
- Cafergot
- carvedilol
- carvedilol phosphate
- Combigan
- Compound 347
- Coreg
- Coreg Cr
- Corgard
- Corzide
- Cosopt
- Cosopt Pf
- Cycloset
- D.h.e.45
- dihydroergotamine
- dorzolamide-timolol
- dorzolamide-timolol (PF)
- Dutoprol
- enflurane
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- Forane
- Inderal La
- Inderal Xl
- Innopran Xl
- isoflurane
- Istalol
- labetalol
- Lopressor
- Lopressor Hct
- methylergonovine
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Migergot
- Migranal
- nadolol
- nadolol-bendroflumethiazide
- Parlodel
- pindolol
- propranolol
- propranolol-hydrochlorothiazid
- Sectral
- sevoflurane
- Sojourn
- Tenoretic 100
- Tenoretic 50
- Tenormin
- Terrell
- timolol
- timolol maleate
- timolol maleate (PF)
- Timoptic
- Timoptic Ocudose (pf)
- Timoptic-xe
- Toprol Xl
- Trandate
- Ultane
Severe
Moderate
- acarbose
- Amaryl
- Apidra
- Apidra Solostar
- carbidopa-levodopa-entacapone
- Comtan
- Diabeta
- Duetact
- entacapone
- glimepiride
- glipizide
- glipizide-metformin
- Glucotrol
- Glucotrol Xl
- Glucovance
- glyburide
- glyburide micronized
- glyburide-metformin
- Glynase
- Glyset
- Humalog
- Humalog Kwikpen
- Humalog Mix 50-50
- Humalog Mix 50-50 Kwikpen
- Humalog Mix 75-25
- Humalog Mix 75-25 Kwikpen
- Humulin 70/30
- Humulin N
- Humulin N Kwikpen
- Humulin R
- Humulin R U-500 "Concentrated"
- insulin asp prt-insulin aspart
- insulin aspart
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin lispro
- insulin lispro protam-lispro
- insulin NPH and regular human
- insulin regular hum U-500 conc
- insulin regular human
- Lantus
- Lantus Solostar
- Levemir
- Levemir Flexpen
- methyldopa
- methyldopa-hydrochlorothiazide
- methyldopate
- miglitol
- nateglinide
- Novolin 70/30
- Novolin N
- Novolin R
- Novolog
- Novolog Flexpen
- Novolog Mix 70-30
- Novolog Mix 70-30 Flexpen
- Novolog Penfill
- NPH insulin human recomb
- pioglitazone-glimepiride
- Precose
- Stalevo 100
- Stalevo 125
- Stalevo 150
- Stalevo 200
- Stalevo 50
- Stalevo 75
- Starlix
- tolazamide
- tolbutamide
- None
Contraindicated
- Acute myocardial infarction
- Angina
- Angle-closure glaucoma
- Cardiac arrhythmia
- Cardiogenic shock
- Cerebral arteriosclerosis
- Congenital long QT syndrome
- Coronary artery disease
- Dilated cardiomyopathy
- Hemorrhagic shock
- Hypertension
- Hyperthyroidism
- Sinus tachycardia
Severe
Moderate
- Diabetes mellitus
- Parkinsonism
ADRENALIN (EPINEPHRINE)
- Allergic reaction
- Anaphylaxis
- Mydriasis during ocular surgery
- Septic shock
- None
- Dizziness
- General weakness
- Headache disorder
- Nervousness
- Pallor
- Palpitations
- Symptoms of anxiety
- Tachycardia
- Tremor
More Frequent
Severe
Less Severe
- None
- Hypertension
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Administration site infection
- Angina
- Cardiac arrhythmia
- Cardiomyopathy
- Cerebrovascular accident
- Chest pain
- Extravasation injury
- Gangrene
- Hyperglycemia
- Hypoglycemic disorder
- Hypokalemia
- Intracranial bleeding
- Kidney disease with reduction in GFR
- Lactic acidosis
- Myocardial ischemia
- Necrotizing fasciitis
- Paradoxical bronchospasm
- Pulmonary edema
- Supraventricular tachycardia
- Ventricular arrhythmias
- Ventricular fibrillation
- Ventricular premature beats
Less Severe
- Acute confusion
- Agitation
- Apprehension
- Blanching of skin
- Drowsy
- Hyperhidrosis
- Hypesthesia
- Injection site sequelae
- Memory impairment
- Nausea
- Oliguria
- Panic disorder
- Paresthesia
- Pilomotor abnormalities
- Vomiting
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Epinephrine
- Severity Level:
2
- Additional Notes: Insufficient human data available
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Epinephrine
Poor oral bioavailability and short half-life; unlikely to affect infant.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Poor oral bioavailability and short half-life; unlikely to affect infant. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Epinephrine
Cardiovascular-Increased risk of cardiovascular side effects: tachycardia, Neuro/Psych-Increased risk of neuropsychological adverse events.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Allergic reaction | |
| T78.40 | Allergy, unspecified |
| T78.40xA | Allergy, unspecified, initial encounter |
| Anaphylaxis | |
| T78.0 | Anaphylactic reaction due to food |
| T78.00 | Anaphylactic reaction due to unspecified food |
| T78.00xA | Anaphylactic reaction due to unspecified food, initial encounter |
| T78.01 | Anaphylactic reaction due to peanuts |
| T78.01xA | Anaphylactic reaction due to peanuts, initial encounter |
| T78.02 | Anaphylactic reaction due to shellfish (crustaceans) |
| T78.02xA | Anaphylactic reaction due to shellfish (crustaceans), initial encounter |
| T78.03 | Anaphylactic reaction due to other fish |
| T78.03xA | Anaphylactic reaction due to other fish, initial encounter |
| T78.04 | Anaphylactic reaction due to fruits and vegetables |
| T78.04xA | Anaphylactic reaction due to fruits and vegetables, initial encounter |
| T78.05 | Anaphylactic reaction due to tree nuts and seeds |
| T78.05xA | Anaphylactic reaction due to tree nuts and seeds, initial encounter |
| T78.06 | Anaphylactic reaction due to food additives |
| T78.06xA | Anaphylactic reaction due to food additives, initial encounter |
| T78.07 | Anaphylactic reaction due to milk and dairy products |
| T78.07xA | Anaphylactic reaction due to milk and dairy products, initial encounter |
| T78.08 | Anaphylactic reaction due to eggs |
| T78.08xA | Anaphylactic reaction due to eggs, initial encounter |
| T78.09 | Anaphylactic reaction due to other food products |
| T78.09xA | Anaphylactic reaction due to other food products, initial encounter |
| T78.2 | Anaphylactic shock, unspecified |
| T78.2xxA | Anaphylactic shock, unspecified, initial encounter |
| T80.5 | Anaphylactic reaction due to serum |
| T80.51 | Anaphylactic reaction due to administration of blood and blood products |
| T80.51xA | Anaphylactic reaction due to administration of blood and blood products, initial encounter |
| T80.52 | Anaphylactic reaction due to vaccination |
| T80.52xA | Anaphylactic reaction due to vaccination, initial encounter |
| T80.59 | Anaphylactic reaction due to other serum |
| T80.59xA | Anaphylactic reaction due to other serum, initial encounter |
| T88.6 | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered |
| T88.6xxA | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter |
| Septic shock | |
| R65.21 | Severe sepsis with septic shock |
| T81.44 | Sepsis following a procedure |
| 0-9 | A-Z |
|---|---|
| R65.21 | Severe sepsis with septic shock |
| T78.0 | Anaphylactic reaction due to food |
| T78.00 | Anaphylactic reaction due to unspecified food |
| T78.00xA | Anaphylactic reaction due to unspecified food, initial encounter |
| T78.01 | Anaphylactic reaction due to peanuts |
| T78.01xA | Anaphylactic reaction due to peanuts, initial encounter |
| T78.02 | Anaphylactic reaction due to shellfish (crustaceans) |
| T78.02xA | Anaphylactic reaction due to shellfish (crustaceans), initial encounter |
| T78.03 | Anaphylactic reaction due to other fish |
| T78.03xA | Anaphylactic reaction due to other fish, initial encounter |
| T78.04 | Anaphylactic reaction due to fruits and vegetables |
| T78.04xA | Anaphylactic reaction due to fruits and vegetables, initial encounter |
| T78.05 | Anaphylactic reaction due to tree nuts and seeds |
| T78.05xA | Anaphylactic reaction due to tree nuts and seeds, initial encounter |
| T78.06 | Anaphylactic reaction due to food additives |
| T78.06xA | Anaphylactic reaction due to food additives, initial encounter |
| T78.07 | Anaphylactic reaction due to milk and dairy products |
| T78.07xA | Anaphylactic reaction due to milk and dairy products, initial encounter |
| T78.08 | Anaphylactic reaction due to eggs |
| T78.08xA | Anaphylactic reaction due to eggs, initial encounter |
| T78.09 | Anaphylactic reaction due to other food products |
| T78.09xA | Anaphylactic reaction due to other food products, initial encounter |
| T78.2 | Anaphylactic shock, unspecified |
| T78.2xxA | Anaphylactic shock, unspecified, initial encounter |
| T78.40 | Allergy, unspecified |
| T78.40xA | Allergy, unspecified, initial encounter |
| T80.5 | Anaphylactic reaction due to serum |
| T80.51 | Anaphylactic reaction due to administration of blood and blood products |
| T80.51xA | Anaphylactic reaction due to administration of blood and blood products, initial encounter |
| T80.52 | Anaphylactic reaction due to vaccination |
| T80.52xA | Anaphylactic reaction due to vaccination, initial encounter |
| T80.59 | Anaphylactic reaction due to other serum |
| T80.59xA | Anaphylactic reaction due to other serum, initial encounter |
| T81.44 | Sepsis following a procedure |
| T88.6 | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered |
| T88.6xxA | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter |
Formulary Reference Tool