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PREZISTA (DARUNAVIR ETHANOLATE)
- HIV infection
150 mg tablet
- Dosage information is not available
600 mg tablet
- 1 tablet (600 mg) by oral route 2 times per day with food
75 mg tablet
- Dosage information is not available
800 mg tablet
- 1 tablet (800 mg) by oral route once daily with food
100 mg/mL oral suspension
- 8 milliliters (800 mg) by oral route once daily with food
HIV infection
- 1 tablet (600 mg) by oral route 2 times per day with food
- 6 milliliters (600 mg) by oral route 2 times per day with food
- 1 tablet (800 mg) by oral route once daily with food
- 8 milliliters (800 mg) by oral route once daily with food
- Advicor
- alfuzosin
- Altoprev
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Belladonna-phenobarbital
- bromocriptine
- cabergoline
- Cafergot
- calcium-mag-B complex-D3-hrb61
- Cerebyx
- Cold & Flu Fighter
- Cycloset
- D.h.e.45
- dihydroergotamine
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- dronedarone
- dutasteride-tamsulosin
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- ezetimibe-simvastatin
- Fatigue Relief Complex
- Flomax
- fosphenytoin
- isoniazid-rifamp-pyrazinamide
- Jalyn
- Juxtapid
- lomitapide
- lovastatin
- Luminal
- methylergonovine
- Mevacor
- midazolam
- midazolam (PF)
- Migergot
- Migranal
- Multaq
- Mysoline
- niacin-lovastatin
- niacin-simvastatin
- Orap
- Parlodel
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- pimozide
- primidone
- Rapaflo
- Revatio
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- sildenafil
- silodosin
- Simcor
- simvastatin
- St. John's wort
- tamsulosin
- triazolam
- Uroxatral
- vit C-St. John wort-elder-hb30
- Vytorin 10-10
- Vytorin 10-20
- Vytorin 10-40
- Vytorin 10-80
- Women's Complex
- Zocor
Contraindicated
- Altavera (28)
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- Apri
- Aranelle (28)
- Astagraf Xl
- Aubra
- Aviane
- Azurette (28)
- B6-FA-B12-co Q10-herb no.225
- Balziva (28)
- Beauty & Skin Therapy
- Beyaz
- bosentan
- Bosulif
- bosutinib
- Brevicon (28)
- Briellyn
- Camila
- Camrese
- Camrese Lo
- carbamazepine
- Carbatrol
- Caziant (28)
- Chateal
- colchicine
- colchicine-probenecid
- Colcrys
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- cyclosporine
- cyclosporine modified
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- Depo-provera
- Depo-subq Provera 104
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- drospirenone-e.estradiol-lm.FA
- drospirenone-ethinyl estradiol
- Elinest
- Emoquette
- Enpresse
- Enskyce
- Epitol
- Equetro
- Errin
- Estarylla
- estradiol valerate-dienogest
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- Falmina (28)
- Femcon Fe
- Fortavit
- Generess Fe
- Gengraf
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- guanfacine
- Healthy Heart Complex
- Heather
- Hecoria
- ibrutinib
- Imbruvica
- Incivek
- Introvale
- Intuniv Er
- Invirase
- Jencycla
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kaletra
- Kariva (28)
- Kelnor 1/35 (28)
- Kurvelo
- L norgest&E estradiol-E estrad
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- lopinavir-ritonavir
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- Maximum Daily Green
- medroxyprogesterone
- Megavite
- Megavite Golden Years 55+
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Minastrin 24 Fe
- Mircette (28)
- Mirena
- Modicon (28)
- Mono-linyah
- Mononessa (28)
- MSM-collag-co Q10-herb no.226
- multivit-Fe-min-DNA-RNA-dsup4
- mv-iron-FA-Ca-beepoln-hb 101
- mv-mn-FA-herbs190&215-digest#4
- mv-mn-FA-lycopene-lut-#178herb
- mv-mn-iron-FA-herbal cmplx#190
- My Way
- Mycobutin
- Myzilra
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- Neoral
- Nexplanon
- Next Choice One Dose
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Nuvaring
- Ocella
- Ogestrel (28)
- Olysio
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- Philith
- Pimtrea (28)
- Pirmella
- Plan B One-step
- policosan-inositol niac-garlic
- Policosanol-garlic-niacin
- Portia
- Previfem
- Priftin
- Prograf
- Quartette
- Quasense
- Rapamune
- Reclipsen (28)
- rifabutin
- rifapentine
- Safyral
- Samsca
- Sandimmune
- saquinavir mesylate
- Seasonique
- simeprevir
- sirolimus
- Skyla
- Sprintec (28)
- Sronyx
- Syeda
- tacrolimus
- Tegretol
- Tegretol Xr
- telaprevir
- temsirolimus
- Tenex
- Tilia Fe
- tolvaptan
- Torisel
- Tracleer
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- Trinessa (28)
- Trivora (28)
- Velivet Triphasic Regimen (28)
- Vestura (28)
- Vfend
- Vfend Iv
- Viorele (28)
- voriconazole
- Vyfemla (28)
- Wera (28)
- Wymzya Fe
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- Abstral
- Actiq
- Afinitor
- Afinitor Disperz
- Alfenta
- alfentanil
- amiodarone
- amiodarone in dextrose,iso-osm
- amlodipine-atorvastatin
- amoxicil-clarithromy-lansopraz
- atorvastatin
- avanafil
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- Caduet
- cilostazol
- clarithromycin
- Cordarone
- Crestor
- dextromethorphan-quinidine
- didanosine
- Duragesic
- Endocet
- Endodan
- everolimus
- Ez Use Joint-tunnel-trigger
- ezetimibe-atorvastatin
- fentanyl
- fentanyl citrate
- fentanyl citrate (PF)
- Fentora
- ibuprofen-oxycodone
- itraconazole
- ivacaftor
- Kalydeco
- ketoconazole
- Latuda
- Lazanda
- Levitra
- lidocaine (PF)
- lidocaine in D5W (PF)
- Lipitor
- Liptruzet
- lurasidone
- Nexterone
- Nuedexta
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Onmel
- Oxecta
- oxycodone
- oxycodone-acetaminophen
- oxycodone-aspirin
- Oxycontin
- Pacerone
- Percocet
- Percodan
- Pletal
- Pravachol
- pravastatin
- Prevpac
- Primlev
- quinidine gluconate
- quinidine sulfate
- rosuvastatin
- Roxicet
- Sporanox
- Sporanox Pulsepak
- Stendra
- Sublimaze (pf)
- Subsys
- triamcinolone-lidocaine
- vardenafil
- Viagra
- Videx 2 Gram Pediatric
- Videx 4 Gram Pediatric
- Videx Ec
- Xartemis Xr
- Xylocaine (cardiac) (pf)
- Zortress
- Lactating mother
Contraindicated
- Disease of liver
Severe
Moderate
- Diabetes mellitus
- Hemophilia
- Hypercholesterolemia
- Hypertriglyceridemia
PREZISTA (DARUNAVIR ETHANOLATE)
- HIV infection
- None
- Acute abdominal pain
- Diarrhea
- Headache disorder
- Hyperlipidemia
- Nausea
- Skin rash
- Vomiting
More Frequent
Severe
Less Severe
- Abdominal distension
- Increased alanine transaminase
- Increased aspartate transaminase
- Anorexia
- Dyspepsia
- Fatigue
- Flatulence
- Pruritus of skin
- Urticaria
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute generalized exanthematous pustulosis
- Acute pancreatitis
- Allergic dermatitis
- Angioedema
- Autoimmune hepatitis
- Avascular necrosis of bone
- DRESS syndrome
- Eosinophilia
- Erythema multiforme
- Graves' disease
- Hepatic failure
- Hepatitis
- Hypersensitivity drug reaction
- Maculopapular rash
- Polymyositis
- Stevens-johnson syndrome
- Toxic epidermal necrolysis
Less Severe
- Arthralgias
- Diabetes mellitus
- Dream disorder
- Fever
- General weakness
- Hypercholesterolemia
- Hyperglycemia
- Hypertriglyceridemia
- Lipodystrophy associated with HIV
- Myalgias
- Skin inflammation
Contraindicated
None
Severe Precaution
Darunavir
Potential increased risk for toxicity based on observed juvenile animal toxicity and mortality. Not recommended per manufacturer.
- 1 Day – 3 Years
- Potential increased risk for toxicity based on observed juvenile animal toxicity and mortality. Not recommended per manufacturer.
Management or Monitoring Precaution
None
Darunavir
- Severity Level:
2
- Additional Notes: Epidemiological studies/ post-market data suggest no increased risk of birth def
Contraindicated
Darunavir
Cdc does not recommend breastfeeding in hiv-positive women.
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Cdc does not recommend breastfeeding in hiv-positive women. |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| HIV infection | |
| B20 | Human immunodeficiency virus [HIv] disease |
| B97.35 | Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
| 0-9 | A-Z |
|---|---|
| B20 | Human immunodeficiency virus [HIv] disease |
| B97.35 | Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
Formulary Reference Tool