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Drug overview for MEGATOPE (albumin, iodinated i-131):
Generic name: albumin, iodinated I-131
Drug class:
Therapeutic class: Diagnostic Agents
No enhanced Introduction information available for this drug.
No enhanced Uses information available for this drug.
Generic name: albumin, iodinated I-131
Drug class:
Therapeutic class: Diagnostic Agents
No enhanced Introduction information available for this drug.
No enhanced Uses information available for this drug.
DRUG IMAGES
No Image Available
The following indications for MEGATOPE (albumin, iodinated i-131) have been approved by the FDA:
Indications:
Diagnostic imaging
Professional Synonyms:
Diagnostic imaging exam
Diagnostic imaging procedure
Diagnostic radiography
Diagnostic radiology
Indications:
Diagnostic imaging
Professional Synonyms:
Diagnostic imaging exam
Diagnostic imaging procedure
Diagnostic radiography
Diagnostic radiology
The following dosing information is available for MEGATOPE (albumin, iodinated i-131):
No enhanced Dosing information available for this drug.
No enhanced Administration information available for this drug.
No dosing information available.
No generic dosing information available.
The following drug interaction information is available for MEGATOPE (albumin, iodinated i-131):
There are 0 contraindications.
There are 1 severe interactions.
These drug interactions can produce serious consequences in most patients. Actions required for severe interactions include, but are not limited to, discontinuing one or both agents, adjusting dosage, altering administration scheduling, and providing additional patient monitoring. Review the full interaction monograph for more information.
| Drug Interaction | Drug Names |
|---|---|
| Radioactive Iodide/Agents that Affect Iodide SEVERITY LEVEL: 2-Severe Interaction: Action is required to reduce the risk of severe adverse interaction. MECHANISM OF ACTION: Many compounds can affect iodide protein binding and alter iodide pharmacokinetics and pharmacodynamics.(1) CLINICAL EFFECTS: Compounds that affect iodide pharmacokinetics and pharmacodynamics may impact the effectiveness of radioactive iodide.(1) PREDISPOSING FACTORS: Compounds that affect iodide pharmacokinetics and pharmacodynamics are expected to have the most impact during therapy using radioactive iodide. Diagnostic procedures would be expected to be impacted less. PATIENT MANAGEMENT: Discuss the use of agents that affect iodide pharmacokinetics and pharmacodynamics with the patient's oncologist.(1) Because indocyanine green contains sodium iodide, the iodine-binding capacity of thyroid tissue may be reduced for at least one week following administration. Do not perform radioactive iodine uptake studies for at least one week following administration of indocyanine green.(2) The manufacturer of iopamidol states administration may interfere with thyroid uptake of radioactive iodine and decrease therapeutic and diagnostic efficacy. Avoid thyroid therapy or testing for up to 6 weeks post administration of iopamidol.(3) DISCUSSION: Many agents interact with radioactive iodine. The average duration of effect is: anticoagulants - 1 week antihistamines - 1 week anti-thyroid drugs, e.g: carbimazole, methimazole, propylthiouracil - 3-5 days corticosteroids - 1 week iodide-containing medications, e.g: amiodarone - 1-6 months expectorants - 2 weeks Lugol solution - 3 weeks saturated solution of potassium iodine - 3 weeks vitamins - 10-14 days iodide-containing X-ray contrast agents - up to 1 year lithium - 4 weeks phenylbutazone - 1-2 weeks sulfonamides - 1 week thyroid hormones (natural or synthetic), e.g.: thyroxine - 4 weeks tri-iodothyronine - 2 weeks tolbutamide - 1 week topical iodide - 1-9 months (1) |
ADDAMEL N, ADTHYZA, ADVAIR DISKUS, ADVAIR HFA, AGAMREE, AIRDUO DIGIHALER, AIRDUO RESPICLICK, AIRSUPRA, ALKINDI SPRINKLE, ALVESCO, AMIODARONE HCL, AMIODARONE HCL-D5W, ARMONAIR DIGIHALER, ARMOUR THYROID, ARNUITY ELLIPTA, ASMANEX, ASMANEX HFA, AZELASTINE HCL, AZELASTINE-FLUTICASONE, AZULFIDINE, BACTRIM, BACTRIM DS, BECLOMETHASONE DIPROPIONATE, BETA 1, BETALOAN SUIK, BETAMETHASONE ACETATE MICRO, BETAMETHASONE ACETATE-SOD PHOS, BETAMETHASONE DIPROPIONATE, BETAMETHASONE SOD PHOS-ACETATE, BETAMETHASONE SOD PHOS-WATER, BETAMETHASONE SODIUM PHOSPHATE, BETAMETHASONE VALERATE, BREO ELLIPTA, BREYNA, BREZTRI AEROSPHERE, BROMFED DM, BROMPHENIRAMINE MALEATE, BROMPHENIRAMINE-PSEUDOEPHED-DM, BSP 0820, BUDESONIDE, BUDESONIDE DR, BUDESONIDE EC, BUDESONIDE ER, BUDESONIDE MICRONIZED, BUDESONIDE-FORMOTEROL FUMARATE, BUPIVACAINE-DEXAMETH-EPINEPHRN, CARBINOXAMINE MALEATE, CARBINOXAMINE MALEATE ER, CELESTONE, CETIRIZINE HCL, CHLORPHENIRAMINE MALEATE, CLARINEX, CLARINEX-D 12 HOUR, CLEMASTINE FUMARATE, CLEMASZ, CLIOQUINOL, CLOBETASOL PROPIONATE MICRO, CONRAY, CONRAY-30, CONRAY-43, CORTEF, CORTISONE ACETATE, CYPROHEPTADINE HCL, CYTOMEL, DATSCAN, DEFLAZACORT, DEPO-MEDROL, DESLORATADINE, DESONIDE MICRONIZED, DESOXIMETASONE, DEXABLISS, DEXAMETHASONE, DEXAMETHASONE ACETATE, DEXAMETHASONE ACETATE MICRO, DEXAMETHASONE INTENSOL, DEXAMETHASONE ISONICOTINATE, DEXAMETHASONE MICRONIZED, DEXAMETHASONE SOD PHOS-WATER, DEXAMETHASONE SODIUM PHOSPHATE, DEXAMETHASONE-0.9% NACL, DEXCHLORPHENIRAMINE MALEATE, DIATRIZOATE MEGLUMINE-SODIUM, DICLEGIS, DIPHEN, DIPHENHYDRAMINE HCL, DIPHENHYDRAMINE-0.9% NACL, DMT SUIK, DOUBLEDEX, DOXYLAMINE SUCC-PYRIDOXINE HCL, DULERA, DYMISTA, EMFLAZA, EOHILIA, ERMEZA, EUTHYROX, FEXOFENADINE HCL, FLUNISOLIDE, FLUOCINOLONE ACETONIDE, FLUOCINOLONE ACETONIDE MICRO, FLUOCINONIDE MICRONIZED, FLUTICASONE PROPIONATE, FLUTICASONE PROPIONATE HFA, FLUTICASONE PROPIONATE MICRO, FLUTICASONE-SALMETEROL, FLUTICASONE-SALMETEROL HFA, FLUTICASONE-VILANTEROL, GASTROGRAFIN, HEMADY, HEXATRIONE, HYDROCODONE-CHLORPHENIRAMNE ER, HYDROCORTISONE, HYDROCORTISONE SOD SUCCINATE, HYDROXYZINE HCL, HYDROXYZINE PAMOATE, IBUPROFEN-FAMOTIDINE, IC GREEN, IDOXURIDINE, INDOCYANINE GREEN, IODINE, IODIXANOL, IODOFORM, IODOPEN, IODOQUINOL, IOFLUPANE I-123, IOMERON 350, IOPAMIDOL, IOPANOIC ACID, ISOPROPAMIDE IODIDE, ISOVUE-200, ISOVUE-250, ISOVUE-300, ISOVUE-370, JANTOVEN, KARBINAL ER, KENALOG-10, KENALOG-40, KENALOG-80, LEVO-T, LEVOCETIRIZINE DIHYDROCHLORIDE, LEVOTHYROXINE SODIUM, LEVOXYL, LIDOCIDEX-I, LIOTHYRONINE SODIUM, LIPIODOL, LITHIUM CARBONATE, LITHIUM CARBONATE ER, LITHIUM CITRATE, LITHIUM CITRATE TETRAHYDRATE, LITHOBID, LORATADINE, LORATADINE MICRONIZED, LUGOL'S, MAS CARE-PAK, MD-GASTROVIEW, MEDROL, MEDROLOAN II SUIK, MEDROLOAN SUIK, METHIMAZOLE, METHYLPREDNISOLONE, METHYLPREDNISOLONE AC MICRO, METHYLPREDNISOLONE ACETATE, METHYLPREDNISOLONE SODIUM SUCC, MILLIPRED, MILLIPRED DP, MOMETASONE FUROATE, NEXTERONE, NIVA THYROID, NP THYROID, OLOPATADINE HCL, OMNARIS, OMNIPAQUE, OPTIRAY 240, OPTIRAY 300, OPTIRAY 320, OPTIRAY 350, ORAPRED ODT, ORTIKOS, OXILAN-350, PACERONE, PEDIAPRED, PEDITRACE, PHENERGAN, PHENIRAMINE MALEATE, PHENYLBUTAZONE, POTASSIUM IODIDE, POVIDONE IODINE, PREDNISOLONE, PREDNISOLONE SODIUM PHOS ODT, PREDNISOLONE SODIUM PHOSPHATE, PREDNISONE, PREDNISONE INTENSOL, PRO-C-DURE 5, PRO-C-DURE 6, PROMETHAZINE HCL, PROMETHAZINE HCL-0.9% NACL, PROMETHAZINE VC, PROMETHAZINE-CODEINE, PROMETHAZINE-DM, PROMETHAZINE-PHENYLEPHRINE HCL, PROPYLTHIOURACIL, PS1 ACIURGY PACK, PS2 ACIURGY PACK, PULMICORT, PULMICORT FLEXHALER, PYRILAMINE MALEATE, QNASL, QNASL CHILDREN, QUZYTTIR, QVAR REDIHALER, RAYOS, RENTHYROID, RESPA A.R., RYALTRIS, RYCLORA, RYVENT, SINOGRAFIN, SINUVA, SOLU-CORTEF, SOLU-MEDROL, SPY AGENT GREEN, SPY-MIS, SSKI, STRONG IODINE, SULFADIAZINE, SULFAMETHOXAZOLE-TRIMETHOPRIM, SULFASALAZINE, SULFASALAZINE DR, SULFATRIM, SYMBICORT, SYNTHROID, TAPERDEX, TARPEYO, THYMOL IODIDE, THYQUIDITY, THYROID, TICANASE, TIROSINT, TIROSINT-SOL, TRELEGY ELLIPTA, TRIAMCINOLONE, TRIAMCINOLONE ACETONIDE, TRIAMCINOLONE DIACETATE, TRIAMCINOLONE DIACETATE MICRO, TRILOAN II SUIK, TRILOAN SUIK, TUXARIN ER, UCERIS, ULTRAVIST, UNITHROID, VERIPRED 20, VISIPAQUE, WARFARIN SODIUM, WIXELA INHUB, XHANCE, ZCORT, ZETONNA, ZILRETTA |
There are 0 moderate interactions.
The following contraindication information is available for MEGATOPE (albumin, iodinated i-131):
Drug contraindication overview.
No enhanced Contraindications information available for this drug.
No enhanced Contraindications information available for this drug.
There are 1 contraindications.
Absolute contraindication.
| Contraindication List |
|---|
| Lactation |
There are 0 severe contraindications.
There are 0 moderate contraindications.
The following adverse reaction information is available for MEGATOPE (albumin, iodinated i-131):
Adverse reaction overview.
No enhanced Common Adverse Effects information available for this drug.
No enhanced Common Adverse Effects information available for this drug.
There are 1 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. | None. |
| Rare/Very Rare |
|---|
|
Hypersensitivity drug reaction |
There are 0 less severe adverse reactions.
The following precautions are available for MEGATOPE (albumin, iodinated i-131):
No enhanced Pediatric Use information available for this drug.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
No enhanced Pregnancy information available for this drug.
No enhanced Lactation information available for this drug.
No enhanced Geriatric Use information available for this drug.
The following prioritized warning is available for MEGATOPE (albumin, iodinated i-131):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for MEGATOPE (albumin, iodinated i-131)'s list of indications:
No ICD codes found for this drug.
No ICD codes found for this drug.
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