NIX (permethrin)

There are 0 contraindications.

There are 0 severe contraindications.

There are 1 moderate contraindications. Clinically significant contraindication, where the condition can be managed or treated before the drug may be given safely.

Moderate List
Bronchospastic pulmonary disease

There are 0 severe adverse reactions.

There are 8 less severe adverse reactions.

More Frequent	Less Frequent
None.	None.

Rare/Very Rare
Eczema Head sensation disturbance Paresthesia Pruritus of skin Skin inflammation Skin irritation Skin rash Stinging of skin

Reproduction studies in mice, rats, and rabbits using oral permethrin dosages of 200-400 mg/kg daily did not impair fertility or cause harm to the fetus. There are no adequate and controlled studies to date using topical permethrin in pregnant women, and the drug should be used during pregnancy only when clearly needed. The CDC and some clinicians consider permethrin 5% a drug of choice for the treatment pediculosis or scabies in pregnant or lactating women. Pregnant women should be advised to consult their clinician before self-medicating with topical permethrin.

It is not known whether permethrin is distributed into human milk. Because many drugs are distributed in milk and because of the tumorigenic potential of permethrin in animal studies, a decision should be made whether to discontinue nursing temporarily or to withhold the drug while the mother is nursing, taking into account the importance of the drug to the woman. Nursing mothers should be advised to consult their clinician before self-medicating with topical permethrin.

No enhanced Geriatric Use information available for this drug.