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PERSERIS (risperidone)
- Schizophrenia
120 mg abdominal subcutaneous extend release susp syringe kit
- Inject 120 mg by subcutaneous route once a month in the abdomen
90 mg abdominal subcutaneous extend release susp syringe kit
- Inject 90 mg by subcutaneous route once a month in the abdomen
Schizophrenia
- Inject 90 mg by subcutaneous route once in the abdomen
- Inject 120 mg by subcutaneous route once in the abdomen
- Inject 90 mg by subcutaneous route once a month in the abdomen
- Inject 120 mg by subcutaneous route once a month in the abdomen
- metoclopramide HCl
- Metozolv Odt
- Reglan
Contraindicated
- cabergoline
Severe
Moderate
- Alagesic Lq
- amobarbital
- Amytal
- Aplenzin
- Apokyn
- apomorphine
- Ascomp With Codeine
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Belladonna-phenobarbital
- Brisdelle
- Bupap
- Buproban
- bupropion HBr
- bupropion HCl
- butabarbital
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-acetaminop-caf-cod
- butalbital-acetaminophen
- butalbital-acetaminophen-caff
- butalbital-aspirin-caffeine
- Butisol
- calcium-mag-B complex-D3-hrb61
- Capacet
- carbamazepine
- Carbatrol
- carbidopa-levodopa
- carbidopa-levodopa-entacapone
- Cerebyx
- codeine-butalbital-ASA-caff
- Cold & Flu Fighter
- Comtan
- Cymbalta
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- duloxetine
- entacapone
- enzalutamide
- Epitol
- Equetro
- Esgic
- Fatigue Relief Complex
- Fioricet
- Fioricet With Codeine
- Fiorinal
- Fiorinal-codeine #3
- fluoxetine
- Forfivo Xl
- fosphenytoin
- isoniazid-rifamp-pyrazinamide
- Luminal
- Lysodren
- Margesic
- Marten-tab
- Mirapex
- Mirapex Er
- mitotane
- Mycobutin
- Mysoline
- Nembutal Sodium
- olanzapine-fluoxetine
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- pentobarbital sodium
- Pexeva
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- pramipexole
- primidone
- Prozac
- Prozac Weekly
- Requip
- Requip Xl
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- ropinirole
- Sarafem
- secobarbital sodium
- Seconal Sodium
- Sinemet
- Sinemet Cr
- St. John's wort
- Stalevo 100
- Stalevo 125
- Stalevo 150
- Stalevo 200
- Stalevo 50
- Stalevo 75
- Symbyax
- Tegretol
- Tegretol Xr
- Tencon
- vit C-St. John wort-elder-hb30
- Wellbutrin
- Wellbutrin Sr
- Wellbutrin Xl
- Women's Complex
- Xtandi
- Zebutal
- Zyban
- Agranulocytosis
- Congenital long QT syndrome
- Neuroleptic malignant syndrome
Contraindicated
- Acute myocardial infarction
- Atherosclerotic cardiovascular disease
- Cardiac arrhythmia
- Cataract surgery
- Cerebrovascular accident
- Cerebrovascular disorder
- Chronic heart failure
- Chronic kidney disease stage 3A (moderate) GFR 45-59
- Chronic kidney disease stage 3B (moderate) GFR 30-44
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Dehydration
- Diffuse lewy body disease
- Disease of liver
- Hypotension
- Hypovolemia
- Leukopenia
- Myocardial ischemia
- Neutropenic disorder
- Orthostatic hypotension
- Parkinsonism
- Rhabdomyolysis
- Senile dementia
- Severe hepatic disease
- Tardive dyskinesia
Severe
Moderate
- Acute confusion
- Carcinoma of breast
- Diabetes mellitus
- Drug abuse
- Dysphagia
- Fever
- Hyperlipidemia
- Hyperprolactinemia
- Hypothermia
- Intraoperative floppy iris syndrome
- Metabolic syndrome X
- Obesity
- Predisposition to aspiration
- Priapism
- Seizure disorder
- Urinary retention
- Weight gain
PERSERIS (risperidone)
- Schizophrenia
- Acquired dystonia
- Akathisia
- Extrapyramidal disease
- Parkinsonism
- Agitation
- Constipation
- Diarrhea
- Dizziness
- Drowsy
- Dyspepsia
- Fatigue
- Headache disorder
- Increased appetite
- Musculoskeletal pain
- Nasal congestion
- Rhinitis
- Sedation
- Sialorrhea
- Skin rash
- Tremor
- Upper respiratory infection
- Weight gain
- Xerostomia
More Frequent
Severe
Less Severe
- SIADH syndrome
- Tachycardia
- Acne vulgaris
- Cough
- Hyperlipidemia
- Hypertriglyceridemia
- Hypesthesia
- Injection site sequelae
- Insomnia
- Myalgias
- Nausea
- Orthostatic hypotension
- Pain
- Peripheral edema
- Pharyngitis
- Sinusitis
- Sore throat
- Toothache
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Accidental fall
- Agranulocytosis
- Anaphylaxis
- Anemia
- Angioedema
- Atrial fibrillation
- Bundle branch block
- Cerebrovascular accident
- Chest pain
- Depression
- Diabetes mellitus
- DRESS syndrome
- Drug-induced psychosis
- Dyspnea
- Esophageal dysmotility
- Heart block
- Hyperglycemia
- Hypertension
- Hypoglycemic disorder
- Hypokinesia
- Hypotension
- Hypothermia
- Ileus
- Jaundice
- Leukopenia
- Neuroleptic malignant syndrome
- Neutropenic disorder
- Pancreatitis
- Priapism
- Retinal vascular occlusion
- Seizure disorder
- Sinus bradycardia
- Sleep apnea
- Tardive dyskinesia
- Thrombotic thrombocytopenic purpura
- Urinary retention
Less Severe
- Abscess
- Acute abdominal pain
- Alopecia
- Amenorrhea
- Anorexia
- Arthralgias
- Ataxia
- Back pain
- Blurred vision
- Complex sleep behavior
- Conjunctivitis
- Disorder of ejaculation
- Dry skin
- Dysarthria
- Dysgeusia
- Dysphagia
- Earache
- Eczema
- Erectile dysfunction
- Eyelid edema
- Fever
- Flushing
- Gastritis
- General weakness
- Hematoma
- Hyperprolactinemia
- Hypertonia
- Libido changes
- Limb pain
- Mastalgia
- Menstrual disorder
- Muscle weakness
- Neck pain
- Nervousness
- Nightmares
- Palpitations
- Paresthesia
- Pruritus of skin
- Reduced visual acuity
- Rhinorrhea
- Salivary secretion disorder
- Symptoms of anxiety
- Syncope
- Tinnitus
- Urinary incontinence
- Vertigo
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Risperidone (Inj)
No information on effects of growth and sexual maturation with long term use. Dose form not studied in pediatrics.
- 1 Day – 18 Years
- No information on effects of growth and sexual maturation with long term use. Dose form not studied in pediatrics.
Risperidone
- Severity Level:
2
- Additional Notes: Non-teratogenic complications (resp, gi,cns) with exposure during 3rd trimester
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Risperidone
Limited data suggest low levels excreted w/no know adverse effect in infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest low levels excreted w/no know adverse effect in infant |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Risperidone (injection)
Neuro/Psych-Inc risk of tardive dyskinesia. CNS effects; sedation, cognitive impairment, and increased fall risk. Avoid use for behavioral probs of dementia or delirium unless failed nonpharm options. Inc risk of stroke, cognitive decline, and death when used with senile dementia. Endocrine-May exacerbate or cause SIADH or hyponatremia. Cardiovascular-May cause orthostatic hypotension. Gastrointestinal-May cause or worsen constipation. Renal-Titrate carefully w/renal impairment.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | Y | N | Y |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- There may be a slightly increased risk of serious, possibly fatal side effects (such as stroke, heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.
| Schizophrenia | |
| F20 | Schizophrenia |
| F20.0 | Paranoid schizophrenia |
| F20.1 | Disorganized schizophrenia |
| F20.2 | Catatonic schizophrenia |
| F20.3 | Undifferentiated schizophrenia |
| F20.5 | Residual schizophrenia |
| F20.8 | Other schizophrenia |
| F20.81 | Schizophreniform disorder |
| F20.89 | Other schizophrenia |
| F20.9 | Schizophrenia, unspecified |
| 0-9 | A-Z |
|---|---|
| F20 | Schizophrenia |
| F20.0 | Paranoid schizophrenia |
| F20.1 | Disorganized schizophrenia |
| F20.2 | Catatonic schizophrenia |
| F20.3 | Undifferentiated schizophrenia |
| F20.5 | Residual schizophrenia |
| F20.8 | Other schizophrenia |
| F20.81 | Schizophreniform disorder |
| F20.89 | Other schizophrenia |
| F20.9 | Schizophrenia, unspecified |
Formulary Reference Tool