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NITROGLYCERIN IN D5W (NITROGLYCERIN/DEXTROSE 5 % IN WATER)
- Perioperative hypertension
- Unstable angina pectoris
- Induction of intraoperative hypotension
- Left ventricular dysfunction following MI
nitroglycerin 100 mg/250 mL (400 mcg/mL) in 5 % dextrose intravenous
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
nitroglycerin 200 mg/500 mL (400 mcg/mL) in 5 % dextrose intravenous
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
nitroglycerin 25 mg/250 mL (100 mcg/mL) in 5 % dextrose intravenous
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
nitroglycerin 50 mg/250 mL (200 mcg/mL) in 5 % dextrose intravenous
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
nitroglycerin 50 mg/500 mL (100 mcg/mL) in 5 % dextrose intravenous
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
Acute coronary syndrome
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
Induction of intraoperative hypotension
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
Perioperative hypertension
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
Severe uncontrolled hypertension
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
Unstable angina pectoris
- Infuse 5 mcg/minute by intravenous route ; titrate to effect by 5 mcg/min every 3-5 minutes up to 20 mcg/min, then titrate by 10-20 mcg/min
- Adcirca
- Adempas
- avanafil
- Cialis
- Levitra
- Revatio
- riociguat
- sildenafil
- Stendra
- tadalafil
- vardenafil
- Viagra
Contraindicated
- Activase
- alteplase
- bromocriptine
- Cafergot
- Cycloset
- D.h.e.45
- dihydroergotamine
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- methylergonovine
- Migergot
- Migranal
- Parlodel
Severe
Moderate
- None
- Constrictive pericarditis
- Intracranial hypertension
- Pericardial tamponade
- Restrictive cardiomyopathy
Contraindicated
- Hypotension
- Intracerebral hemorrhage
- Methemoglobinemia
- Severe anemia
Severe
Moderate
- Hypertrophic cardiomyopathy
NITROGLYCERIN IN D5W (NITROGLYCERIN/DEXTROSE 5 % IN WATER)
- Perioperative hypertension
- Unstable angina pectoris
- Induction of intraoperative hypotension
- Left ventricular dysfunction following MI
- Syncope
- Dizziness
- Flushing
- Headache disorder
- Hypotension
- Nervousness
- Orthostatic hypotension
- Paresthesia
More Frequent
Severe
Less Severe
- None
- Nausea
- Palpitations
- Tachycardia
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Allergic dermatitis
- Anaphylaxis
- Blurred vision
- Exfoliative dermatitis
- Methemoglobinemia
- Severe headache disorder
- Xerostomia
Less Severe
- Drowsy
- Dyspnea
- General weakness
- Skin rash
- Vertigo
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Nitroglycerin
- Severity Level:
2
- Additional Notes: Insuff human data; animal data do not suggest developmental toxicity
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Nitroglycerin
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Nitroglycerin
Cardiovascular-Start at low end of dosing range. May be more sensitive to the hypotensive effects of vasodilation.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
| Induction of intraoperative hypotension | |
| I95.89 | Other hypotension |
| Left ventricular dysfunction following MI | |
| I23.8 | Other current complications following acute myocardial infarction |
| I50.1 | Left ventricular failure, unspecified |
| Perioperative hypertension | |
| I97.3 | Postprocedural hypertension |
| Unstable angina pectoris | |
| I20.0 | Unstable angina |
| I25.110 | Atherosclerotic heart disease of native coronary artery with unstable angina pectoris |
| I25.700 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris |
| I25.710 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unstable angina pectoris |
| I25.720 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unstable angina pectoris |
| I25.730 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unstable angina pectoris |
| I25.750 | Atherosclerosis of native coronary artery of transplanted heart with unstable angina |
| I25.760 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unstable angina |
| I25.790 | Atherosclerosis of other coronary artery bypass graft(s) with unstable angina pectoris |
| 0-9 | A-Z |
|---|---|
| I20.0 | Unstable angina |
| I23.8 | Other current complications following acute myocardial infarction |
| I25.110 | Atherosclerotic heart disease of native coronary artery with unstable angina pectoris |
| I25.700 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris |
| I25.710 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unstable angina pectoris |
| I25.720 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unstable angina pectoris |
| I25.730 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unstable angina pectoris |
| I25.750 | Atherosclerosis of native coronary artery of transplanted heart with unstable angina |
| I25.760 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unstable angina |
| I25.790 | Atherosclerosis of other coronary artery bypass graft(s) with unstable angina pectoris |
| I50.1 | Left ventricular failure, unspecified |
| I95.89 | Other hypotension |
| I97.3 | Postprocedural hypertension |
Formulary Reference Tool