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ENALAPRILAT (ENALAPRILAT DIHYDRATE)
- Hypertension
1.25 mg/mL intravenous solution
- Inject 1 milliliter (1.25 mg) over 5 minute(s) by intravenous route every 6 hours
1.25 mg/mL intravenous solution
- Inject 1 milliliter (1.25 mg) over 5 minute(s) by intravenous route every 6 hours
Hypertension
- Inject 1 milliliter (1.25 mg) over 5 minute(s) by intravenous route every 6 hours
Hypertensive crisis
- Inject 0.5 milliliter (0.625 mg) by intravenous route every 6 hours as needed
- Inject 1 milliliter (1.25 mg) by intravenous route every 6 hours as needed
- None
Contraindicated
- aliskiren
- aliskiren-amlodipin-hcthiazide
- aliskiren-amlodipine
- aliskiren-hydrochlorothiazide
- Amturnide
- Curad Enema
- Disposable Enema
- Enema
- Enema Disposable
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- lithium carbonate
- lithium citrate
- Lithobid
- Oral Saline Laxative
- Osmoprep
- Phosphate Laxative
- Preparation Cleansing
- Ready-to-use Enema
- sod phos mono-sod phos dibasic
- sodium phosphates
- Tekamlo
- Tekturna
- Tekturna Hct
Severe
Moderate
- Added Strength Headache Relief
- Added Strength Pain Reliever
- Alka-seltzer
- Alka-seltzer Extra Strength
- Alka-seltzer Original
- Alka-seltzer Plus C/c(pe,dm)
- Alka-seltzer Plus Cold (pe)
- Alka-seltzer Plus Day-night
- Alka-seltzer Plus Night
- Alka-seltzer Pm
- Anacin
- Anacin Maximum Strength
- Analgesic
- Angeliq
- Antacid & Pain Relief
- ASA-acetaminophen-caff-buffers
- ASA-acetaminophen-salicyl-caff
- Ascomp With Codeine
- Aspir-trin
- aspirin
- aspirin, buffered
- aspirin-acetaminophen-caffeine
- aspirin-caffeine
- aspirin-diphenhydramine
- aspirin-diphenhydramine citrat
- aspirin-sod bicarb-citric acid
- Azasan
- azathioprine
- azathioprine sodium
- Back & Body Pain Reliever
- Bactrim
- Bactrim Ds
- Bayer Advanced
- Bayer Aspirin
- Bayer Aspirin (with Caffeine)
- Bayer Back & Body
- Bayer Plus Extra Strength
- Bayer Pm
- Bc
- Bc Arthritis
- Beyaz
- Buffered Aspirin
- Bufferin
- bumetanide
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-aspirin-caffeine
- carisoprodol-ASA-codeine
- carisoprodol-aspirin
- chlorphen-phenyleph-DM-aspirin
- chlorphenir-phenylephrn-aspirn
- codeine-butalbital-ASA-caff
- Cold Relief
- Cold Relief Plus
- Demadex
- dihydrocodeine-aspirin-caff
- doxylamine-phenylep-DM-aspirin
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- E.c. Prin
- Ecotrin
- Efferves Pain Relief Antacid
- Effervescent Antacid
- Effervescent Pain Relief
- Effervescent Pain Reliever
- Endodan
- ethacrynate sodium
- Excedrin Extra Strength
- Excedrin Migraine
- Extra Strength Bayer
- Fiorinal
- Fiorinal-codeine #3
- furosemide
- Gianvi (28)
- Goody's Extra Strength
- Goody's Migraine Relief
- Headache Formula
- Headache Formula Added Str
- Headache Relief
- Imuran
- Lasix
- Levacet
- Lite Coat Aspirin
- Loryna (28)
- Medi-seltzer
- mercaptopurine
- Migraine Formula
- Migraine Pain Reliever
- Migraine Relief
- Ocella
- Orphenadrine Compound Forte
- Orphenadrine Compound-ds
- orphenadrine-ASA-caffeine
- oxycodone-aspirin
- Pain Relief
- Pain Relief Extra Strength
- Pain Reliever
- Pain Reliever Extra Strength
- Pain Reliever Plus
- Pain-off
- Pamprin Max
- PE-DM-ASA/doxyla-PE-DM-ASA
- Percodan
- Primsol
- Purinethol
- Safyral
- Sodium Edecrin
- sulfamethoxazole-trimethoprim
- Sulfatrim
- Super Pain Relief
- Syeda
- Synalgos-dc
- torsemide
- Tri-buffered Aspirin
- trimethoprim
- Vanquish
- Vestura (28)
- Yasmin (28)
- Yaz 28
- Zarah
- Angioedema
- Hereditary angioedema
- Hypotension
- Pregnancy
Contraindicated
- Hemodialysis with high-flux membrane
- Hyperkalemia
- Hyponatremia
- Kidney disease with reduction in GFR
- Neutropenic disorder
- Renal artery stenosis
Severe
Moderate
- Aortic valve stenosis
- Bone marrow depression
- Cerebrovascular insufficiency
- Disease of liver
- Hypertrophic cardiomyopathy
- Immunosuppression
- Recipient of organ transplant
ENALAPRILAT (ENALAPRILAT DIHYDRATE)
- Hypertension
- Hypotension
- Cough
- Dizziness
More Frequent
Severe
Less Severe
- Fever
- Hyperkalemia
- Arthralgias
- Bronchitis
- Diarrhea
- Dysgeusia
- Dyspnea
- Fatigue
- General weakness
- Headache disorder
- Orthostatic hypotension
- Skin rash
- Syncope
- Vertigo
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Acute pancreatitis
- Acute renal failure
- Agranulocytosis
- Anaphylaxis
- Angioedema
- Atrial fibrillation
- Bradycardia
- Bronchospastic pulmonary disease
- Chest pain
- Drug-induced hepatitis
- Eosinophilia
- Eosinophilic pneumonia
- Erythema multiforme
- Exfoliative dermatitis
- Head and neck angioedema
- Ileus
- Intestinal angioedema
- Laryngeal edema
- Leukocytosis
- Myositis
- Neutropenic disorder
- Obstructive hyperbilirubinemia
- Pemphigus
- Pharyngeal edema
- Pulmonary edema
- Pulmonary thromboembolism
- Stevens-johnson syndrome
- Tachycardia
- Thrombocytopenic disorder
- Tongue swelling
- Toxic epidermal necrolysis
- Vasculitis
Less Severe
- Acute confusion
- Anorexia
- Ataxia
- Black tarry stools
- Blurred vision
- Conjunctivitis
- Constipation
- Cramps
- Depression
- Drowsy
- Dyspepsia
- Erectile dysfunction
- Flushing
- Glossitis
- Gynecomastia
- Hyperhidrosis
- Loss of sense of smell
- Myalgias
- Pruritus of skin
- Raynaud's phenomenon
- Skin photosensitivity
- Stomatitis
- Tinnitus
- Urticaria
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Enalaprilat (Inj)
Safety and efficacy in pediatrics have not been established.
- 1 Day – 18 Years
- Safety and efficacy in pediatrics have not been established.
Enalapril
- Severity Level:
1
- Additional Notes: Fetal death/morbidity w/use in 2nd & 3rd trimester, stop when pregnancy detected
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Enalapril
Limited data suggest minimal excretion resulting in no adv effects in infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest minimal excretion resulting in no adv effects in infant |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Enalaprilat
Monitor for hypotension, increased serum creatinine or hyperkalemia.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool