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AMIDATE (ETOMIDATE)
- Administration of general anesthesia
- General anesthesia adjunct
- Etomidate Intravenous Solution
- Amidate Intravenous Syringe
- Amidate Intravenous Solution
- By Indication
2 mg/mL intravenous solution
- Inject 0.3 mg/kg by intravenous route once
2 mg/mL intravenous syringe
- Inject 0.3 mg/kg by intravenous route once
2 mg/mL intravenous solution
- Inject 0.3 mg/kg by intravenous route once
Administration of general anesthesia
- Inject 0.2 mg/kg by intravenous route x1 dose
- Inject 0.3 mg/kg by intravenous route once
- Inject 0.6 mg/kg by intravenous route once
General anesthesia adjunct
- Inject 0.2 mg/kg by intravenous route x1 dose
- Inject 0.3 mg/kg by intravenous route once
- Inject 0.6 mg/kg by intravenous route once
- None
Contraindicated
- sodium oxybate
- Xyrem
Severe
Moderate
- None
- None
Contraindicated
- Adrenal cortical insufficiency
- Hypotension
Severe
Moderate
- None
AMIDATE (ETOMIDATE)
- Administration of general anesthesia
- General anesthesia adjunct
- Nausea
- Vomiting
- Injection site sequelae
- Involuntary muscle movement
More Frequent
Severe
Less Severe
- None
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Bradycardia
- Bradypnea
- Hypertension
- Hyperventilation
- Hypotension
- Hypoventilation
- Laryngismus
- Tachycardia
- Tachypnea
Less Severe
- Hiccups
- Snoring
Contraindicated
None
Severe Precaution
Etomidate
Risk of long-term cognitive deficits with use > 3 hours if age < 3 years. Inadequate safety data age < 10 years. Not recommended per manufacturer.
- 1 Day – 10 Years
- Risk of long-term cognitive deficits with use > 3 hours if age < 3 years. Inadequate safety data age < 10 years. Not recommended per manufacturer.
Management or Monitoring Precaution
None
Etomidate
- Severity Level:
2
- Additional Notes: Insuff human data; animal data sug dev tox
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Etomidate
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Etomidate
Increased risk of cardiac depression with underlying hypertension. Use lower dose for renal impairment.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
Formulary Reference Tool