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NIPENT (PENTOSTATIN)
- Hairy cell leukemia
10 mg intravenous solution
- Infuse 4 mg/m2 by intravenous route once
10 mg intravenous solution
- Infuse 4 mg/m2 by intravenous route once
Hairy cell leukemia
- Inject 4 mg/m2 by intravenous route once
- Inject 4 mg/m2 by intravenous route once every 2 weeks
- Infuse 4 mg/m2 by intravenous route once
- Infuse 4 mg/m2 over 20-30 minute(s) by intravenous route once every 2Weeks
Progressive chronic lymphocytic leukemia
- Inject 4 mg/m2 by intravenous route once
- Inject 4 mg/m2 by intravenous route every 3 weeks
- Inject 2 mg/m2 by intravenous route every 3 weeks
- Infuse 4 mg/m2 over 20-30 minute(s) by intravenous route every 3 weeks
- Infuse 2 mg/m2 over 20-30 minute(s) by intravenous route every 3 weeks
- Infuse 4 mg/m2 over 20-30 minute(s) by intravenous route once
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- BCG vaccine, live (PF)
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- typhoid vaccine
- Tysabri
- varicella virus vacc live (PF)
- Varivax (pf)
- Vivotif Berna Vaccine
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- clozapine
- Clozaril
- deferiprone
- Fazaclo
- Ferriprox
- Versacloz
Severe
Moderate
- Arranon
- nelarabine
- Lactating mother
- Pulmonary edema
Contraindicated
- Abnormal hepatic function tests
- Anemia
- Disease of liver
- Hypotension
- Kidney disease with reduction in GFR
- Leukopenia
- Neutropenic disorder
- Pregnancy
- Severe infection
- Thrombocytopenic disorder
Severe
Moderate
- None
NIPENT (PENTOSTATIN)
- Hairy cell leukemia
- Allergic dermatitis
- Anemia
- CNS toxicity
- Disease of liver
- Infection
- Leukopenia
- Thrombocytopenic disorder
- Anorexia
- Diarrhea
- Headache disorder
- Nausea
- Pain
- Pruritus of skin
- Skin rash
- Vomiting
More Frequent
Severe
Less Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Agranulocytosis
- Angina
- Cardiac arrhythmia
- Chronic heart failure
- Dyspnea
- Hemorrhage
- Hypotension
- Keratoconjunctivitis
- Kidney disease with reduction in GFR
- Neutropenic disorder
- Pneumonia
- Pulmonary edema
- Seizure disorder
- Thrombophlebitis
- Urticaria
- Visual changes
- Acute abdominal pain
- Arthralgias
- Back pain
- Bronchitis
- Chest pain
- Chills
- Constipation
- Cough
- Depression
- Drowsy
- Dry skin
- Epistaxis
- Facial edema
- Fatigue
- Flatulence
- General weakness
- Gingivitis
- Hyperhidrosis
- Malaise
- Myalgias
- Nervousness
- Peripheral edema
- Pharyngitis
- Rhinitis
- Sinusitis
- Stomatitis
- Symptoms of anxiety
- Upper respiratory infection
- Weight loss
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute respiratory insufficiency
- Atrioventricular block
- Bradycardia
- Exfoliative dermatitis
- Hemolytic uremic syndrome
- Pericardial effusion
- Thrombotic thrombocytopenic purpura
- Vasculitis
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Pentostatin
Safety and efficacy not established.
- 1 Day – 18 Years
- Safety and efficacy not established.
Pentostatin
- Severity Level:
D
- Additional Notes: Based on animal data, fetal harm may occur.
Contraindicated
Pentostatin
Potential for serious adverse reaction in nursing infant
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Potential for serious adverse reaction in nursing infant |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Hairy cell leukemia | |
| C91.4 | Hairy cell leukemia |
| C91.40 | Hairy cell leukemia not having achieved remission |
| C91.42 | Hairy cell leukemia, in relapse |
| 0-9 | A-Z |
|---|---|
| C91.4 | Hairy cell leukemia |
| C91.40 | Hairy cell leukemia not having achieved remission |
| C91.42 | Hairy cell leukemia, in relapse |
Formulary Reference Tool