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Drug overview for NATACYN (natamycin):
Generic name: NATAMYCIN (NA-ta-MYE-sin)
Drug class: Ophthalmic Antifungals
Therapeutic class: Ophthalmic Agents
Natamycin, a tetraene polyene, is an antifungal agent.
Natamycin 5% ophthalmic suspension is used in the topical treatment of blepharitis, conjunctivitis, and keratitis caused by susceptible fungi, including keratitis caused by Fusarium solani. The effectiveness of topical natamycin used alone in the treatment of fungal endophthalmitis has not been established. The clinical diagnosis, laboratory diagnosis by smear and culture of corneal scrapings, and response to the drug should be used to guide initial and continued therapy of fungal keratitis. Whenever possible, in vitro susceptibility testing should be performed to confirm that the causative organism is susceptible to natamycin.
Generic name: NATAMYCIN (NA-ta-MYE-sin)
Drug class: Ophthalmic Antifungals
Therapeutic class: Ophthalmic Agents
Natamycin, a tetraene polyene, is an antifungal agent.
Natamycin 5% ophthalmic suspension is used in the topical treatment of blepharitis, conjunctivitis, and keratitis caused by susceptible fungi, including keratitis caused by Fusarium solani. The effectiveness of topical natamycin used alone in the treatment of fungal endophthalmitis has not been established. The clinical diagnosis, laboratory diagnosis by smear and culture of corneal scrapings, and response to the drug should be used to guide initial and continued therapy of fungal keratitis. Whenever possible, in vitro susceptibility testing should be performed to confirm that the causative organism is susceptible to natamycin.
DRUG IMAGES
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The following indications for NATACYN (natamycin) have been approved by the FDA:
Indications:
Fungal blepharitis
Fungal conjunctivitis
Fungal keratitis
Professional Synonyms:
None.
Indications:
Fungal blepharitis
Fungal conjunctivitis
Fungal keratitis
Professional Synonyms:
None.
The following dosing information is available for NATACYN (natamycin):
No enhanced Dosing information available for this drug.
No enhanced Administration information available for this drug.
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| NATACYN 5% EYE DROPS | Maintenance | Adults instill 1 drop into affected eye(s) by ophthalmic route 4 times per day |
No generic dosing information available.
The following drug interaction information is available for NATACYN (natamycin):
There are 0 contraindications.
There are 0 severe interactions.
There are 0 moderate interactions.
The following contraindication information is available for NATACYN (natamycin):
Drug contraindication overview.
No enhanced Contraindications information available for this drug.
No enhanced Contraindications information available for this drug.
There are 0 contraindications.
There are 0 severe contraindications.
There are 1 moderate contraindications.
Clinically significant contraindication, where the condition can be managed or treated before the drug may be given safely.
| Moderate List |
|---|
| No disease contraindications |
The following adverse reaction information is available for NATACYN (natamycin):
Adverse reaction overview.
No enhanced Common Adverse Effects information available for this drug.
No enhanced Common Adverse Effects information available for this drug.
There are 6 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. | None. |
| Rare/Very Rare |
|---|
|
Chemosis Chest pain Conjunctival hyperemia Corneal opacity Dyspnea Paresthesia |
There are 6 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. |
Ocular irritation |
| Rare/Very Rare |
|---|
|
Eye tearing Foreign body sensation of eye Ocular discomfort Ocular pain Visual changes |
The following precautions are available for NATACYN (natamycin):
No enhanced Pediatric Use information available for this drug.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
No enhanced Pregnancy information available for this drug.
No enhanced Lactation information available for this drug.
No enhanced Geriatric Use information available for this drug.
The following prioritized warning is available for NATACYN (natamycin):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for NATACYN (natamycin)'s list of indications:
| Fungal blepharitis | |
| H01.0 | Blepharitis |
| H01.00 | Unspecified blepharitis |
| H01.001 | Unspecified blepharitis right upper eyelid |
| H01.002 | Unspecified blepharitis right lower eyelid |
| H01.003 | Unspecified blepharitis right eye, unspecified eyelid |
| H01.004 | Unspecified blepharitis left upper eyelid |
| H01.005 | Unspecified blepharitis left lower eyelid |
| H01.006 | Unspecified blepharitis left eye, unspecified eyelid |
| H01.009 | Unspecified blepharitis unspecified eye, unspecified eyelid |
| H01.00A | Unspecified blepharitis right eye, upper and lower eyelids |
| H01.00B | Unspecified blepharitis left eye, upper and lower eyelids |
| H01.01 | Ulcerative blepharitis |
| H01.011 | Ulcerative blepharitis right upper eyelid |
| H01.012 | Ulcerative blepharitis right lower eyelid |
| H01.013 | Ulcerative blepharitis right eye, unspecified eyelid |
| H01.014 | Ulcerative blepharitis left upper eyelid |
| H01.015 | Ulcerative blepharitis left lower eyelid |
| H01.016 | Ulcerative blepharitis left eye, unspecified eyelid |
| H01.019 | Ulcerative blepharitis unspecified eye, unspecified eyelid |
| H01.01A | Ulcerative blepharitis right eye, upper and lower eyelids |
| H01.01B | Ulcerative blepharitis left eye, upper and lower eyelids |
| H01.02 | Squamous blepharitis |
| H01.021 | Squamous blepharitis right upper eyelid |
| H01.022 | Squamous blepharitis right lower eyelid |
| H01.023 | Squamous blepharitis right eye, unspecified eyelid |
| H01.024 | Squamous blepharitis left upper eyelid |
| H01.025 | Squamous blepharitis left lower eyelid |
| H01.026 | Squamous blepharitis left eye, unspecified eyelid |
| H01.029 | Squamous blepharitis unspecified eye, unspecified eyelid |
| H01.02A | Squamous blepharitis right eye, upper and lower eyelids |
| H01.02B | Squamous blepharitis left eye, upper and lower eyelids |
| Fungal conjunctivitis | |
| H10.02 | Other mucopurulent conjunctivitis |
| H10.021 | Other mucopurulent conjunctivitis, right eye |
| H10.022 | Other mucopurulent conjunctivitis, left eye |
| H10.023 | Other mucopurulent conjunctivitis, bilateral |
| H10.029 | Other mucopurulent conjunctivitis, unspecified eye |
| H10.3 | Unspecified acute conjunctivitis |
| H10.30 | Unspecified acute conjunctivitis, unspecified eye |
| H10.31 | Unspecified acute conjunctivitis, right eye |
| H10.32 | Unspecified acute conjunctivitis, left eye |
| H10.33 | Unspecified acute conjunctivitis, bilateral |
| Fungal keratitis | |
| H16.06 | Mycotic corneal ulcer |
| H16.061 | Mycotic corneal ulcer, right eye |
| H16.062 | Mycotic corneal ulcer, left eye |
| H16.063 | Mycotic corneal ulcer, bilateral |
| H16.069 | Mycotic corneal ulcer, unspecified eye |
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