LANOXIN (DIGOXIN)
- Chronic heart failure
- Ventricular rate control in atrial fibrillation
125 mcg (0.125 mg) tablet
- 1 tablet (125 mcg) by oral route once daily
187.5 mcg (0.1875 mg) tablet
- 1 tablet (187.5 mcg) by oral route once daily
250 mcg (0.25 mg) tablet
- 1 tablet (250 mcg) by oral route once daily
62.5 mcg (0.0625 mg) tablet
- 2 tablets (125 mcg) by oral route once daily
125 mcg (0.125 mg) tablet
- 1 tablet (125 mcg) by oral route once daily
187.5 mcg (0.1875 mg) tablet
- 1 tablet (187.5 mcg) by oral route once daily
250 mcg (0.25 mg) tablet
- 1 tablet (250 mcg) by oral route once daily
62.5 mcg (0.0625 mg) tablet
- 2 tablets (125 mcg) by oral route once daily
125 mcg (0.125 mg) tablet
- 1 tablet (125 mcg) by oral route once daily
187.5 mcg (0.1875 mg) tablet
- 1 tablet (187.5 mcg) by oral route once daily
250 mcg (0.25 mg) tablet
- 1 tablet (250 mcg) by oral route once daily
62.5 mcg (0.0625 mg) tablet
- 2 tablets (125 mcg) by oral route once daily
in 125 mcg (0.125 mg) tablet
- 1 tablet (125 mcg) by oral route once daily
in 187.5 mcg (0.1875 mg) tablet
- 1 tablet (187.5 mcg) by oral route once daily
in 250 mcg (0.25 mg) tablet
- 1 tablet (250 mcg) by oral route once daily
in 62.5 mcg (0.0625 mg) tablet
- 2 tablets (125 mcg) by oral route once daily
125 mcg (0.125 mg) tablet
- 1 tablet (125 mcg) by oral route once daily
250 mcg (0.25 mg) tablet
- 1 tablet (250 mcg) by oral route once daily
125 mcg (0.125 mg) tablet
- 1 tablet (125 mcg) by oral route once daily
250 mcg (0.25 mg) tablet
- 1 tablet (250 mcg) by oral route once daily
Chronic heart failure
- 1 tablet (125 mcg) by oral route once daily
- 2 tablets (125 mcg) by oral route once daily
- 1 tablet (187.5 mcg) by oral route once daily
- 2 tablets (250 mcg) by oral route once daily
- 1 tablet (250 mcg) by oral route once daily
- 2 tablets (375 mcg) by oral route once daily
- 2 tablets (500 mcg) by oral route once daily
Ventricular rate control in atrial fibrillation
- 1 tablet (125 mcg) by oral route once daily
- 2 tablets (125 mcg) by oral route once daily
- 1 tablet (187.5 mcg) by oral route once daily
- 2 tablets (250 mcg) by oral route once daily
- 1 tablet (250 mcg) by oral route once daily
- 2 tablets (375 mcg) by oral route once daily
- 2 tablets (500 mcg) by oral route once daily
- None
Contraindicated
- Abelcet
- Ambisome
- amino acids 2.75%-lytes-Ca-D10
- amino acids 2.75%-lytes-Ca-D5W
- amino acids 4.25%-lytes-Ca-D10
- amino acids 4.25%-lytes-Ca-D25
- amino acids 4.25%-lytes-Ca-D5W
- amino acids 5 %-lytes-Ca-D20W
- amino acids 5 %-lytes-Ca-D25W
- amino acids 5%-lytes-Ca-D15W
- amiodarone
- amiodarone in dextrose,iso-osm
- amoxicil-clarithromy-lansopraz
- amphotericin B lipid complex
- amphotericin B liposome
- azithromycin
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- Calan
- Calan Sr
- calcium chloride
- Calcium Disodium Versenate
- clarithromycin
- Clinimix E 2.75%/d10W Sul Free
- Clinimix E 2.75%/d5W Sulf Free
- Clinimix E 4.25%/d10W Sul Free
- Clinimix E 4.25%/d25W Sul Free
- Clinimix E 4.25%/d5W Sulf Free
- Clinimix E 5%/d15W Sulfit Free
- Clinimix E 5%/d20W Sulfit Free
- Clinimix E 5%/d25W Sulfit Free
- Cordarone
- cyclosporine
- cyclosporine modified
- dextromethorphan-quinidine
- dronedarone
- edetate calcium disodium
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- fingolimod
- flecainide
- Gengraf
- Gilenya
- hydroxychloroquine
- Hyperlyte Cr
- itraconazole
- Ketek
- ketoconazole
- Multaq
- Neoral
- Nexterone
- Nuedexta
- Nutrilyte Ii
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Onmel
- Pacerone
- Plaquenil
- potassium chloride in LR-D5
- Prevpac
- propafenone
- Provenge
- quinidine gluconate
- quinidine sulfate
- ringers
- Rythmol
- Sandimmune
- sipuleucel-T in LR
- sodium-K+-mag-Ca-chlor-acetate
- Sporanox
- Sporanox Pulsepak
- Tarka
- telithromycin
- Tpn Electrolytes
- Tpn Electrolytes Ii
- trandolapril-verapamil
- verapamil
- Verelan
- Verelan Pm
- Zithromax
- Zithromax Tri-pak
- Zithromax Z-pak
- Zmax
Severe
Moderate
- acarbose
- Accuretic
- Acid Controller Complete
- Acid Gone
- Acid Gone Antacid
- Acid Reducer Complete (famot)
- Adalat Cc
- Adoxa
- Adriamycin
- Adriamycin Pfs
- Advanced Antacid-antigas
- Advicor
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Afeditab Cr
- Al hyd-Mg tr-alg ac-sod bicarb
- Aldactazide
- Aldactone
- aliskiren-amlodipin-hcthiazide
- aliskiren-hydrochlorothiazide
- Almacone
- Almacone-2
- Altoprev
- alum-mag hydroxide-simeth
- aluminum hydrox-magnesium carb
- aluminum hydroxide gel
- aluminum-magnesium hydroxide
- amiloride-hydrochlorothiazide
- amlodipine-atorvastatin
- amlodipine-valsartan-hcthiazid
- Amturnide
- Antacid
- Antacid Anti-gas
- Antacid Anti-gas Double Str
- Antacid Extra Strength
- Antacid Extra-strength
- Antacid Ii Plus Simethicone
- Antacid Liquid
- Antacid M
- Antacid Maximum Strength
- Antacid Multi-symptom
- Antacid Plus Anti-gas
- Antacid Plus Extra Strength
- Antacid Regular Strength
- Antacid Supreme
- Antacid Tablet
- Antacid With Simethicone
- Antacid-antigas
- Antacid-antigas Ii
- Antacid-simethicone
- Antacid-simethicone Ds
- Armour Thyroid
- ASA-acetaminophen-caff-buffers
- aspirin, buffered
- Atacand Hct
- atenolol-chlorthalidone
- atorvastatin
- Avalide
- Avidoxy
- azilsartan med-chlorthalidone
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Bayer Plus Extra Strength
- benazepril-hydrochlorothiazide
- Benicar Hct
- Bicnu
- bisoprolol-hydrochlorothiazide
- bleomycin
- boceprevir
- Buffered Aspirin
- Bufferin
- bumetanide
- Caduet
- cal phos-mag hydrx-C & D3-phos
- calcium & magnesium carbonates
- calcium carb-mag hydrox-simeth
- calcium carbonate-mag hydroxid
- calcium-mag-B complex-D3-hrb61
- Caldolor
- candesartan-hydrochlorothiazid
- captopril-hydrochlorothiazide
- Carafate
- Cardene Iv
- Cardene Iv In Dextrose
- Cardene Iv In Sodium Chloride
- Cardene Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- carmustine
- carmustine in polifeprosan
- Cartia Xt
- Cerebyx
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorothiazide
- chlorothiazide sodium
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- chlorthalidone
- cholestyramine (with sugar)
- Cholestyramine Light
- cholestyramine-aspartame
- Citrate Of Magnesia
- Citroma
- clonidine-chlorthalidone
- Clorpres
- Cold & Flu Fighter
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Colestid
- Colestid Flavored
- colestipol
- Comfort Gel
- Comfort Gel Extra Strength
- Complete
- conivaptan in 5 % dextrose
- Corzide
- Crestor
- Cuprimine
- cyclophosphamide
- cytarabine
- cytarabine (PF)
- cytarabine liposome (PF)
- Cytomel
- Demadex
- demeclocycline
- Depen Titratabs
- Depocyt (pf)
- Dilacor Xr
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Dilt-xr
- diltiazem HCl
- diosmin complex no.1
- Diovan Hct
- Diuril
- Diuril Iv
- Doryx
- Doxil
- doxorubicin
- doxorubicin HCl peg-liposomal
- Doxy-100
- doxycycline calcium
- doxycycline hyclate
- doxycycline monohydrate
- Dual Action Complete
- Duexis
- Dutoprol
- Dyazide
- Edarbyclor
- enalapril-hydrochlorothiazide
- eprosartan-hydrochlorothiazide
- Epsom Salt
- ethacrynate sodium
- ethotoin
- Exforge Hct
- ezetimibe-atorvastatin
- ezetimibe-simvastatin
- ezogabine
- famotidine-Ca carb-mag hydrox
- Fatigue Relief Complex
- Flanax
- fluvastatin
- Foaming Antacid
- Foaming Antacid Extra Strength
- fosinopril-hydrochlorothiazide
- fosphenytoin
- furosemide
- Gaviscon
- Gaviscon Extra Strength
- Gelusil Antacid & Anti-gas
- Geri-lanta
- Geri-mox Antacid-antigas
- Gliadel Wafer
- Heartburn Antacid
- hydrochlorothiazide
- hydrocodone-ibuprofen
- Hyzaar
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Incivek
- indapamide
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- irbesartan-hydrochlorothiazide
- isoniazid-rifamp-pyrazinamide
- kaolin-pectin
- lapatinib
- Lasix
- Lescol
- Lescol Xl
- levothyroxine
- Levoxyl
- liothyronine
- liotrix
- Lipitor
- Lipodox
- Lipodox 50
- Liptruzet
- Liquid Antacid
- lisinopril-hydrochlorothiazide
- Lopressor Hct
- losartan-hydrochlorothiazide
- lovastatin
- Maalox Advanced
- Maalox Maximum Strength
- Mag-al
- Mag-al Plus
- Mag-al Plus Extra Strength
- Maglox
- magnesium citrate
- magnesium hydroxide
- magnesium sulfate (laxative)
- magnesium-aluminum-alginic ac
- Marqibo
- Masanti Double Strength
- Matulane
- Matzim La
- Maxzide
- Maxzide-25Mg
- Medi-profen
- methimazole
- Methotrexate (anti-rheumatic)
- methotrexate sodium
- methotrexate sodium (PF)
- methyclothiazide
- methyldopa-hydrochlorothiazide
- metoclopramide HCl
- metolazone
- metoprolol su-hydrochlorothiaz
- metoprolol ta-hydrochlorothiaz
- Metozolv Odt
- Mevacor
- Mi-acid
- Micardis Hct
- Microzide
- Milk Of Magnesia
- Milk Of Magnesia Concentrated
- Minocin
- minocycline
- Mintox
- Mintox Maximum Strength
- Mintox Plus
- moexipril-hydrochlorothiazide
- Monodox
- Morgidox
- Motrin Ib
- Motrin Pm
- Mycobutin
- nadolol-bendroflumethiazide
- Nature-throid
- neomycin
- Neoprofen (ibuprofen Lysn)(pf)
- niacin-lovastatin
- niacin-simvastatin
- nicardipine
- nicardipine in dextrose,iso-os
- nicardipine in NaCl (iso-os)
- Nifedical Xl
- nifedipine
- Np Thyroid
- olmesartan-amlodipin-hcthiazid
- olmesartan-hydrochlorothiazide
- Oracea
- paromomycin
- Pedia-lax
- PEG 3350-bowel 2,two part prep
- Peganone
- penicillamine
- Pepcid Complete
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Phillips Milk Of Magnesia
- Potiga
- Pravachol
- pravastatin
- Precose
- Prevalite
- Priftin
- Pro-cal
- procarbazine
- Procardia
- Procardia Xl
- propranolol-hydrochlorothiazid
- propylthiouracil
- Provil
- pseudoephedrine-ibuprofen
- Qualaquin
- Questran
- Questran Light
- quinapril-hydrochlorothiazide
- quinine sulfate
- Reglan
- Reprexain
- Rheumatrex
- Ri-gel
- Ri-gel Ii
- Ri-mox
- Ri-mox Plus
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- Riginic
- rosuvastatin
- Rulox
- Simcor
- simvastatin
- Sodium Edecrin
- sodium,potassium,&mag sulfates
- Solodyn
- spironolacton-hydrochlorothiaz
- spironolactone
- St. John's wort
- Suclear
- sucralfate
- Supreme Antacid
- Suprep
- Synthroid
- Tapazole
- Taztia Xt
- Tekturna Hct
- telaprevir
- telmisartan-hydrochlorothiazid
- Tenoretic 100
- Tenoretic 50
- tetracycline
- Teveten Hct
- thyroid (pork)
- Thyrolar-1
- Thyrolar-1/2
- Thyrolar-1/4
- Thyrolar-2
- Thyrolar-3
- Tiazac
- Tirosint
- torsemide
- Trexall
- Tri-buffered Aspirin
- triamterene-hydrochlorothiazid
- Tribenzor
- Triostat
- Tums Dual Action
- Tykerb
- Uniretic
- Unithroid
- valsartan-hydrochlorothiazide
- Vanquish
- Vaprisol
- Vasculera
- Vaseretic
- Vibramycin
- Vicoprofen
- Victrelis
- Vincasar Pfs
- vincristine
- vincristine sulfate liposomal
- vit C-St. John wort-elder-hb30
- Vytorin 10-10
- Vytorin 10-20
- Vytorin 10-40
- Vytorin 10-80
- Wal-profen
- Wal-profen Cold-sinus
- Westhroid
- Women's Complex
- Wp Thyroid
- Zaroxolyn
- Zestoretic
- Ziac
- Zocor
- Ventricular fibrillation
Contraindicated
- Acute myocardial infarction
- Amyloid heart muscle disease
- Atrioventricular block
- Constrictive pericarditis
- Cor pulmonale
- Digitalis toxicity
- Hypercalcemia
- Hypertrophic cardiomyopathy
- Hypokalemia
- Hypomagnesemia
- Kidney disease with likely reduction in GFR
- Myocarditis
- Restrictive cardiomyopathy
- Sick sinus syndrome
- Sinus bradycardia
- Wolff-parkinson-white pattern
Severe
Moderate
- Myxedema
LANOXIN (DIGOXIN)
- Chronic heart failure
- Ventricular rate control in atrial fibrillation
- None
- Gynecomastia
More Frequent
Severe
Less Severe
- Sinus bradycardia
- Nausea
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal ECG
- Allergic dermatitis
- Anorexia
- Atrioventricular block
- Delirium
- Diarrhea
- Heart block
- Intestinal ischemic necrosis
- Skin rash
- Tachyarrhythmia
- Thrombocytopenic disorder
- Ventricular fibrillation
- Ventricular premature beats
- Ventricular tachycardia
- Visual halos
Less Severe
- Acute abdominal pain
- Acute confusion
- Blurred vision
- Depression
- Dizziness
- General weakness
- Hallucinations
- Headache disorder
- Indifference
- Maculopapular rash
- Symptoms of anxiety
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Digitalis
- Severity Level:
2
- Additional Notes: Human data do not suggest adverse effects or developmental toxicity w/ exposure
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
None
General | Excretion Potential | Effect on Infant | Notes |
None |
No Known Risk
Digitalis Glycosides
Limited data suggest low amounts excreted w/ no adverse effect on the infant
General | Excretion Potential | Effect on Infant | Notes |
No known risks; does not adversely affect lactation | Excreted | No adverse effect | Limited data suggest low amounts excreted w/ no adverse effect on the infant |
Contraindicated
None
Precaution Exists
Digitalis Glycosides
General- Avoid as first-line agent in atrial fibrillation or heart failure. Renal-Decreased renal clearance with aging. Use lower starting dose of 0.125 mg and monitor plasma drug levels more frequently. Metabolic-Correct hypokalemia, hypomagnesemia and hypercalcemia to minimize toxicity. Maintain plasma level below 2.0 ng/mL.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- None
Chronic heart failure | |
I50.22 | Chronic systolic (congestive) heart failure |
I50.32 | Chronic diastolic (congestive) heart failure |
I50.42 | Chronic combined systolic (congestive) and diastolic (congestive) heart failure |
I50.812 | Chronic right heart failure |
I50.814 | Right heart failure due to left heart failure |
Ventricular rate control in atrial fibrillation | |
I48.0 | Paroxysmal atrial fibrillation |
I48.1 | Persistent atrial fibrillation |
I48.11 | Longstanding persistent atrial fibrillation |
I48.2 | Chronic atrial fibrillation |
I48.20 | Chronic atrial fibrillation, unspecified |
I48.21 | Permanent atrial fibrillation |
I48.91 | Unspecified atrial fibrillation |
0-9 | A-Z |
---|---|
I48.0 | Paroxysmal atrial fibrillation |
I48.1 | Persistent atrial fibrillation |
I48.11 | Longstanding persistent atrial fibrillation |
I48.2 | Chronic atrial fibrillation |
I48.20 | Chronic atrial fibrillation, unspecified |
I48.21 | Permanent atrial fibrillation |
I48.91 | Unspecified atrial fibrillation |
I50.22 | Chronic systolic (congestive) heart failure |
I50.32 | Chronic diastolic (congestive) heart failure |
I50.42 | Chronic combined systolic (congestive) and diastolic (congestive) heart failure |
I50.812 | Chronic right heart failure |
I50.814 | Right heart failure due to left heart failure |