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VANATOL LQ (BUTALBITAL/ACETAMINOPHEN/CAFFEINE)
- Tension-type headache
50 mg-325 mg-40 mg/15 mL oral solution
- 30 milliliters by oral route every 4 hours as needed not to exceed 180 ml in 24Hrs
50 mg-325 mg-40 mg/15 mL oral solution
- 30 milliliters by oral route every 4 hours as needed not to exceed 180 ml in 24Hrs
Tension-type headache
- 15 milliliters by oral route every 4 hours as needed
- 30 milliliters by oral route every 4 hours as needed not to exceed 180 ml in 24Hrs
- dipyridamole
- sodium oxybate
- Xyrem
Contraindicated
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Adenocard
- Adenoscan
- adenosine
- adenosine (diagnostic)
- Afinitor
- Afinitor Disperz
- Altavera (28)
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- Apri
- Aranelle (28)
- Astagraf Xl
- Aubra
- Aviane
- Azurette (28)
- Balziva (28)
- Beyaz
- Brevicon (28)
- Briellyn
- Camila
- Camrese
- Camrese Lo
- Caziant (28)
- Chateal
- cimetidine
- Coumadin
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- cyclosporine
- cyclosporine modified
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- drospirenone-e.estradiol-lm.FA
- drospirenone-ethinyl estradiol
- Elinest
- Emoquette
- Enpresse
- Enskyce
- Errin
- Estarylla
- estradiol valerate-dienogest
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- everolimus
- Falmina (28)
- Femcon Fe
- Generess Fe
- Gengraf
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- Heartburn Relief
- Heather
- Hecoria
- Introvale
- Jantoven
- Jencycla
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kariva (28)
- Kelnor 1/35 (28)
- Kurvelo
- L norgest&E estradiol-E estrad
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lexiscan
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Minastrin 24 Fe
- Mircette (28)
- Mirena
- Modicon (28)
- Mono-linyah
- Mononessa (28)
- My Way
- Myzilra
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- Neoral
- Nexplanon
- Next Choice One Dose
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Nuvaring
- Ocella
- Ogestrel (28)
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- Philith
- Pimtrea (28)
- Pirmella
- Plan B One-step
- Portia
- Previfem
- Prograf
- Quartette
- Quasense
- quetiapine
- Rapamune
- Reclipsen (28)
- regadenoson
- Safyral
- Samsca
- Sandimmune
- Seasonique
- Seroquel Xr
- sirolimus
- Skyla
- Sprintec (28)
- Sronyx
- Syeda
- tacrolimus
- Tagamet Hb
- temsirolimus
- Tilia Fe
- tolvaptan
- Torisel
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- Trinessa (28)
- Trivora (28)
- Velivet Triphasic Regimen (28)
- Vestura (28)
- Viorele (28)
- Vyfemla (28)
- warfarin
- Wera (28)
- Wymzya Fe
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zortress
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- A-hydrocort
- A-methapred
- Abilify
- Abilify Discmelt
- Abilify Maintena
- acebutolol
- Activella
- Adasuve
- Adoxa
- Alora
- aminophylline
- Angeliq
- Anucort-hc
- Anusol-hc
- aripiprazole
- Aristospan Intra-articular
- Aristospan Intralesional
- Avidoxy
- betamethasone acet & sod phos
- betaxolol
- budesonide
- Celestone Soluspan
- Cenestin
- chlorpromazine
- Climara
- Climara Pro
- Colocort
- Combipatch
- Compazine
- Compro
- conj estrogens-bazedoxifene
- conjugated estrogens
- Cortef
- Cortenema
- Cortifoam
- cortisone
- Covaryx
- Covaryx H.s.
- Delestrogen
- Depo-estradiol
- Depo-medrol
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- dextromethorphan-quinidine
- Divigel
- Doryx
- Doxy-100
- doxycycline calcium
- doxycycline hyclate
- doxycycline monohydrate
- drospirenone-estradiol
- Duavee
- Dutoprol
- Eemt
- Eemt Hs
- Elestrin
- Elixophyllin
- Enjuvia
- Entocort Ec
- esterified estrogens
- Estrace
- estradiol
- estradiol acetate
- estradiol cypionate
- Estradiol Transdermal Patch
- estradiol valerate
- estradiol-levonorgestrel
- estradiol-norethindrone acet
- estradiol-norgestimate
- Estrasorb
- Estring
- Estrogel
- estrogens-methyltestosterone
- estropipate
- Evamist
- Ez Use Joint-tunnel-trigger
- felodipine
- Femhrt Low Dose
- Femring
- First-duke's
- First-mary's Mouthwash
- Flagyl
- Flagyl Er
- Flo-pred
- fludrocortisone
- fluphenazine decanoate
- fluphenazine HCl
- fluvoxamine
- Grx Hicort 25
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- Hemril-30
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- Inderal La
- Inderal Xl
- Innopran Xl
- isoniazid
- isoniazid-rifamp-pyrazinamide
- Jinteli
- Kenalog
- lithium carbonate
- lithium citrate
- Lithobid
- Lopressor
- Lopressor Hct
- loxapine
- loxapine succinate
- Loxitane
- Luvox Cr
- Medrol
- Medrol (pak)
- Menest
- Menostar
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Metro I.v.
- Metrogel Vaginal
- metronidazole
- metronidazole in NaCl (iso-os)
- Millipred
- Millipred Dp
- Mimvey
- Minivelle
- Monodox
- Morgidox
- Nuedexta
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Ogen 2.5
- Oracea
- Orapred
- Orapred Odt
- Pediapred
- perphenazine
- perphenazine-amitriptyline
- Phenadoz
- Phenergan
- Physicians Ez Use M-pred
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- Prefest
- Premarin
- prochlorperazine
- prochlorperazine Edisylate
- prochlorperazine maleate
- Proctocort
- promethazine
- Promethazine Vc
- Promethazine Vc-codeine
- promethazine-codeine
- promethazine-DM
- promethazine-phenyleph-codeine
- promethazine-phenylephrine
- Promethegan
- propranolol
- propranolol-hydrochlorothiazid
- quinidine gluconate
- quinidine sulfate
- Rayos
- Rectacort-hc
- Rifamate
- rifampin-isoniazid
- Rifater
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- Sectral
- Seroquel
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- synthetic conj estrogens A
- synthetic conj estrogens B
- Theo-24
- Theochron
- theophylline
- theophylline in dextrose 5 %
- thioridazine
- Toprol Xl
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- trifluoperazine
- Uceris
- Vagifem
- Vandazole
- Veripred 20
- Vibramycin
- Vivelle-dot
- 30 day risk period post-myocardial infarction
- Acetaminophen overdose
- Acute asthma attack
- Acute hepatic failure
- Acute hepatitis C
- Alcoholism
- Porphyria
- Sleep apnea
Contraindicated
- Acute respiratory insufficiency
- Chronic obstructive pulmonary disease
- Depression
- Disease of liver
- Drug abuse
- Hepatic coma
- Hepatic encephalopathy
- Hyperammonemia
- Necrotizing enterocolitis
- Peptic ulcer
- Protein-calorie malnutrition
- Severe renal impairment
- Shock
- Suicidal ideation
Severe
Moderate
- Anemia
- Cardiac arrhythmia
- Complex sleep behavior
- Disease of liver
- Hyperkinesis
- Hypertension
- Insomnia
- Kidney disease with reduction in GFR
- Neutropenic disorder
- Renal disease with moderate to severe impairment
- Seizure disorder
- Severe hepatic disease
- Thrombocytopenic disorder
VANATOL LQ (BUTALBITAL/ACETAMINOPHEN/CAFFEINE)
- Tension-type headache
- None
- Dizziness
- Drowsy
- Gastrointestinal irritation
- Insomnia
- Nervousness
More Frequent
Severe
Less Severe
- Abnormal hepatic function tests
- Acute confusion
- Excitement
- Lethargy
- Constipation
- Depression
- Excitement
- Headache disorder
- Insomnia
- Irritability
- Nausea
- Nervousness
- Nightmares
- Symptoms of anxiety
- Syncope
- Vertigo
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Accidental fall
- Acute generalized exanthematous pustulosis
- Acute hepatic failure
- Agranulocytosis
- Allergic dermatitis
- Altered consciousness
- Anaphylaxis
- Angioedema
- Apnea
- Bradycardia
- Drug-induced hepatitis
- Dyspnea
- Exfoliative dermatitis
- Extrasystoles
- Hallucinations
- Hypersensitivity drug reaction
- Hypotension
- Hypoventilation
- Laryngeal edema
- Leukopenia
- Maculopapular rash
- Megaloblastic anemia
- Memory impairment
- Neutropenic disorder
- Osteopenia
- Psychiatric disorder
- Rickets
- Skin rash
- Stevens-johnson syndrome
- Throat constriction
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Urticaria
- Wheezing
Less Severe
- Agitation
- Ataxia
- CNS depression
- Complex sleep behavior
- Disturbance in thinking
- Drug dependence
- Erythema
- Hyperesthesia
- Hyperglycemia
- Hyperkinesis
- Irritability
- Medication overuse headache
- Nausea
- Nephrotoxicity
- Scotomata
- Skin rash
- Symptoms of anxiety
- Tachycardia
- Tinnitus
- Tremor
- Urticaria
- Vomiting
Contraindicated
None
Severe Precaution
Butalbital
Safety and effectiveness not established age < 12 years.
- 1 Day – 12 Years
- Safety and effectiveness not established age < 12 years.
Management or Monitoring Precaution
Acetaminophen (oral,rectal)
Use weight based dosing in children less than 12 years.
Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
- 1 Day – 12 Years
- Use weight based dosing in children less than 12 years.
- 1 Day – 364 Days
- Use weight based dosing in children less than 12 years.
- 1 Years – 13 Years
- Use weight based dosing in children less than 12 years.
Caffeine
Use weight based dosing in children less than 12 years.
Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
- 1 Day – 12 Years
- Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
- Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
- 1 Day – 364 Days
- Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
- Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
- 1 Years – 13 Years
- Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
- Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
Acetaminophen
- Severity Level:
2
- Additional Notes: Available data suggest no known risk; otc product, no fda pregnancy warnings
Butalbital
- Severity Level:
C
- Additional Notes: Case report of neonatal withdrawal seizures with butalbital combo product
Caffeine
- Severity Level:
C
- Additional Notes: Reports of miscarriage,poor fetal growth possibly assoc w/high doses of caffeine
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Butalbital
Possibility of central nervous system depression in nursing infant.
High doses may cause hyperactivity and wakefulness in infant.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Drug shown to have adverse effect | Possibility of central nervous system depression in nursing infant. |
Caffeine
Possibility of central nervous system depression in nursing infant.
High doses may cause hyperactivity and wakefulness in infant.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Drug shown to have adverse effect | High doses may cause hyperactivity and wakefulness in infant. |
No Known Risk
Acetaminophen
Low levels excreted with low risk for adverse effects in infant
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | No adverse effect | Low levels excreted with low risk for adverse effects in infant |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day.<br /><br />People with liver problems and children should take less acetaminophen. Ask your doctor or pharmacist how much acetaminophen is safe to take. Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first.<br /><br />Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. Get medical help right away if you take too much acetaminophen (overdose), even if you feel well.<br /><br />Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, and dark urine. Daily alcohol use, especially when combined with acetaminophen, may damage your liver. Avoid alcohol.
| Tension-type headache | |
| G44.2 | Tension-type headache |
| G44.20 | Tension-type headache, unspecified |
| G44.201 | Tension-type headache, unspecified, intractable |
| G44.209 | Tension-type headache, unspecified, not intractable |
| G44.21 | Episodic tension-type headache |
| G44.211 | Episodic tension-type headache, intractable |
| G44.219 | Episodic tension-type headache, not intractable |
| G44.22 | Chronic tension-type headache |
| G44.221 | Chronic tension-type headache, intractable |
| G44.229 | Chronic tension-type headache, not intractable |
| 0-9 | A-Z |
|---|---|
| G44.2 | Tension-type headache |
| G44.20 | Tension-type headache, unspecified |
| G44.201 | Tension-type headache, unspecified, intractable |
| G44.209 | Tension-type headache, unspecified, not intractable |
| G44.21 | Episodic tension-type headache |
| G44.211 | Episodic tension-type headache, intractable |
| G44.219 | Episodic tension-type headache, not intractable |
| G44.22 | Chronic tension-type headache |
| G44.221 | Chronic tension-type headache, intractable |
| G44.229 | Chronic tension-type headache, not intractable |
Formulary Reference Tool