VANACOF (DEXCHLORPHENIRAMINE MALEATE/PSEUDOEPHEDRINE HCL/CHLOPHED HCL)
- Cold symptoms
- Allergic rhinitis
- Cough
- Nasal congestion
- Rhinorrhea
- Vasomotor rhinitis
1 mg-30 mg-12.5 mg/5 mL oral liquid
- 10 milliliters by oral route every 6-8 hours as needed
dexchlorphen-p-phed-chlophedianol 1 mg-30 mg-12.5 mg/5 mL oral liquid
- 10 milliliters by oral route every 6-8 hours as needed
dexchlorphen-p-phed-chlophedianol 2 mg-60 mg-25 mg/5 mL oral liquid
- Dosage information is not available
Allergic rhinitis
- 10 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 8 hours
- 10 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 8 hours as needed
- 10 milliliters by oral route every 6-8 hours as needed
Cold symptoms
- 10 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 8 hours
- 10 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 8 hours as needed
- 10 milliliters by oral route every 6-8 hours as needed
Cough
- 10 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 8 hours
- 10 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 8 hours as needed
- 10 milliliters by oral route every 6-8 hours as needed
Nasal congestion
- 10 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 8 hours
- 10 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 8 hours as needed
- 10 milliliters by oral route every 6-8 hours as needed
Rhinorrhea
- 10 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 8 hours
- 10 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 8 hours as needed
- 10 milliliters by oral route every 6-8 hours as needed
Vasomotor rhinitis
- 10 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 8 hours
- 10 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 8 hours as needed
- 10 milliliters by oral route every 6-8 hours as needed
- isocarboxazid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- tranylcypromine
Contraindicated
- Azilect
- bromocriptine
- cabergoline
- Cafergot
- Cycloset
- D.h.e.45
- dihydroergotamine
- Eldepryl
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- linezolid
- methylergonovine
- Migergot
- Migranal
- Parlodel
- rasagiline
- selegiline HCl
- Zelapar
- Zyvox
Severe
Moderate
- methyldopa
- methyldopa-hydrochlorothiazide
- methyldopate
- reserpine
- Angle-closure glaucoma
- Severe coronary artery disease
- Severe uncontrolled hypertension
- Urinary retention
Contraindicated
- Angle-closure glaucoma
- Benign prostatic hyperplasia
- Bladder outflow obstruction
- Chronic idiopathic constipation
- Diabetes mellitus
- Hypertension
- Hyperthyroidism
- Stenosing peptic ulcer
- Urinary retention
Severe
Moderate
- Debilitation
- Hypertension
- Hyperthyroidism
- Ocular hypertension
VANACOF (DEXCHLORPHENIRAMINE MALEATE/PSEUDOEPHEDRINE HCL/CHLOPHED HCL)
- Cold symptoms
- Allergic rhinitis
- Cough
- Nasal congestion
- Rhinorrhea
- Vasomotor rhinitis
- None
- Dizziness
- Drowsy
- Headache disorder
- Insomnia
- Thick bronchial secretions
More Frequent
Severe
Less Severe
- None
- Agitation
- Anorexia
- Dizziness
- Drowsy
- Dysuria
- General weakness
- Nausea
- Nervousness
- Pallor
- Sedation
- Tachycardia
- Tremor
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute generalized exanthematous pustulosis
- Anaphylaxis
- Blood dyscrasias
- Dyspnea
- Extrasystoles
- Hallucinations
- Hemolytic anemia
- Hypertension
- Hypotension
- Ischemic colitis
- Seizure disorder
- Urticaria
- Vomiting
Less Severe
- Abdominal distension
- Abdominal pain with cramps
- Acute abdominal pain
- Acute confusion
- Anorexia
- Ataxia
- Blurred vision
- Cardiac arrhythmia
- Chest discomfort
- Chills
- Constipation
- Diarrhea
- Diplopia
- Drowsy
- Dry nose
- Dry throat
- Dyspepsia
- Dyspnea
- Dysuria
- Euphoria
- Excitement
- Fatigue
- Hallucinations
- Headache disorder
- Hyperhidrosis
- Insomnia
- Irritability
- Maculopapular rash
- Malaise
- Migraine
- Nausea
- Nervousness
- Nightmares
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin photosensitivity
- Skin rash
- Symptoms of anxiety
- Tachycardia
- Tinnitus
- Tremor
- Urinary retention
- Urticaria
- Vertigo
- Visual changes
- Vomiting
- Wheezing
- Xerostomia
Contraindicated
Chlophedianol
Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
No safety and efficacy age <2 years. CNS excitation and seizure risk in newborns.
Not recommended age < 6 years without clinician consultation.
High risk of adverse CNS effects. Not recommended for use age < 6 years.
- 1 Day – 6 Years
- 1 Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
- 1 Day – 2 Years
- 1 Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
- 2 Years – 6 Years
- 1 Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
Dexchlorpheniramine
Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
No safety and efficacy age <2 years. CNS excitation and seizure risk in newborns.
Not recommended age < 6 years without clinician consultation.
High risk of adverse CNS effects. Not recommended for use age < 6 years.
- 1 Day – 6 Years
- 1 No safety and efficacy age <2 years. CNS excitation and seizure risk in newborns.
- 1 Not recommended age < 6 years without clinician consultation.
- 1 Day – 2 Years
- 1 No safety and efficacy age <2 years. CNS excitation and seizure risk in newborns.
- 1 Not recommended age < 6 years without clinician consultation.
- 2 Years – 6 Years
- 1 No safety and efficacy age <2 years. CNS excitation and seizure risk in newborns.
- 1 Not recommended age < 6 years without clinician consultation.
Pseudoephedrine (Immed. Release)
Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
No safety and efficacy age <2 years. CNS excitation and seizure risk in newborns.
Not recommended age < 6 years without clinician consultation.
High risk of adverse CNS effects. Not recommended for use age < 6 years.
- 1 Day – 6 Years
- 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.
- 1 Day – 2 Years
- 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.
- 2 Years – 6 Years
- 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.
Severe Precaution
None
Management or Monitoring Precaution
None
Chlophedianol
- Severity Level:
C
- Additional Notes: Only available in combination products that are assigned fda category c.
Dexchlorpheniramine Maleate
- Severity Level:
B
- Additional Notes:
Pseudoephedrine
- Severity Level:
C
- Additional Notes: Fda c w/combo prod; poss risk of gastroschisis/sia with 1st trimester exposure
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Chlophedianol
Insufficient data available.
Not recommended. may cause paradoxical excitation/inhibit lactation.
May decrease milk supply, and cause irritability
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available. |
Dexchlorpheniramine Maleate
Insufficient data available.
Not recommended. may cause paradoxical excitation/inhibit lactation.
May decrease milk supply, and cause irritability
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Not known; no or inclusive data | Not recommended. may cause paradoxical excitation/inhibit lactation. |
Pseudoephedrine
Insufficient data available.
Not recommended. may cause paradoxical excitation/inhibit lactation.
May decrease milk supply, and cause irritability
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Drug shown to have adverse effect | May decrease milk supply, and cause irritability |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Dexchlorpheniramine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | N | N | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
Pseudoephedrine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
Allergic rhinitis | |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
Cold symptoms | |
J00 | Acute nasopharyngitis [common cold] |
Cough | |
R05 | Cough |
Nasal congestion | |
R09.81 | Nasal congestion |
Rhinorrhea | |
R09.82 | Postnasal drip |
Vasomotor rhinitis | |
J30.0 | Vasomotor rhinitis |
0-9 | A-Z |
---|---|
J00 | Acute nasopharyngitis [common cold] |
J30.0 | Vasomotor rhinitis |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
R05 | Cough |
R09.81 | Nasal congestion |
R09.82 | Postnasal drip |