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VANACOF CP (pyrilamine maleate/chlophedianol HCl)
- cold symptoms
- cough
- inflammation of the nose due to an allergy
- runny nose
- stuffy nose
25 mg-12.5 mg/15 mL oral liquid
- Dosage information is not available
- None
Contraindicated
- K-tab
- Klor-con
- Klor-con 10
- Klor-con M10
- Klor-con M15
- Klor-con M20
- Medi-lyte
- potassium chloride
- potassium citrate
- potassium Cl-calcium phos-mag
- sodium Cl-potassium chloride
- Thermotabs
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
Severe
Moderate
- None
- None
Contraindicated
- Angle-closure glaucoma
- Benign prostatic hyperplasia
- Bladder outflow obstruction
- Chronic idiopathic constipation
- Stenosing peptic ulcer
- Urinary retention
Severe
Moderate
- Debilitation
- Hypertension
- Hyperthyroidism
- Ocular hypertension
VANACOF CP (pyrilamine maleate/chlophedianol HCl)
- cold symptoms
- cough
- inflammation of the nose due to an allergy
- runny nose
- stuffy nose
- None
- Abdominal pain with cramps
- Drowsy
- Thick bronchial secretions
More Frequent
Severe
Less Severe
- None
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Blood dyscrasias
- Urticaria
Less Severe
- Acute cognitive impairment
- Anorexia
- Anticholinergic toxicity
- Blurred vision
- Dizziness
- Drowsy
- Dry nose
- Dry throat
- Dysuria
- Excitement
- Hallucinations
- Hyperhidrosis
- Irritability
- Nausea
- Nervousness
- Nightmares
- Skin photosensitivity
- Skin rash
- Tachycardia
- Tinnitus
- Vertigo
- Visual changes
- Vomiting
- Xerostomia
Contraindicated
Chlophedianol
Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
Possible CNS excitation and seizure risk in newborns.
Do not use in pediatrics <2 years of age unless clinician consultation.
- 1 Day – 6 Years
- 1 Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
- 1 Day – 29 Days
- 1 Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
- 30 Days – 2 Years
- 1 Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
Pyrilamine
Risk of CNS effects. Not recommended age < 6 years unless clinician consult.
Possible CNS excitation and seizure risk in newborns.
Do not use in pediatrics <2 years of age unless clinician consultation.
- 1 Day – 6 Years
- 1 Possible CNS excitation and seizure risk in newborns.
- 1 Do not use in pediatrics <2 years of age unless clinician consultation.
- 1 Day – 29 Days
- 1 Possible CNS excitation and seizure risk in newborns.
- 1 Do not use in pediatrics <2 years of age unless clinician consultation.
- 30 Days – 2 Years
- 1 Possible CNS excitation and seizure risk in newborns.
- 1 Do not use in pediatrics <2 years of age unless clinician consultation.
Severe Precaution
Pyrilamine
Do not use in pediatrics < 6 years of age unless clinician consultation.
- 2 Years – 6 Years
- Do not use in pediatrics < 6 years of age unless clinician consultation.
Management or Monitoring Precaution
None
Pyrilamine
- Severity Level:
2
- Additional Notes: No fda category; incr risk of retrolental fibroplasia seen in premature infants
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Chlophedianol
Insufficient human data available
Use is not recommended; may cause unusual excitement or irritability
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available |
Pyrilamine
Insufficient human data available
Use is not recommended; may cause unusual excitement or irritability
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Drug shown to have adverse effect | Use is not recommended; may cause unusual excitement or irritability |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Pyrilamine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating antihistamine preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- None
| Allergic rhinitis | |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| Cold symptoms | |
| J00 | Acute nasopharyngitis [common cold] |
| Cough | |
| R05 | Cough |
| R05.1 | Acute cough |
| R05.2 | Subacute cough |
| R05.3 | Chronic cough |
| R05.9 | Cough, unspecified |
| Nasal congestion | |
| R09.81 | Nasal congestion |
| Rhinorrhea | |
| R09.82 | Postnasal drip |
| 0-9 | A-Z |
|---|---|
| J00 | Acute nasopharyngitis [common cold] |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| R05 | Cough |
| R05.1 | Acute cough |
| R05.2 | Subacute cough |
| R05.3 | Chronic cough |
| R05.9 | Cough, unspecified |
| R09.81 | Nasal congestion |
| R09.82 | Postnasal drip |
Formulary Reference Tool