ATRIPLA (efavirenz/emtricitabine/tenofovir disoproxil fumarate)

Moderate

• Advil

• Advil Allergy Sinus

• Advil Allergy-congestion Rlf

• Advil Cold & Sinus

• Advil Congestion Relief

• Advil Liqui-gel

• Advil Migraine

• Advil Pm

• Advil Pm Liqui-gels

• afatinib

• Aleve

• Aleve Cold & Sinus

• Aleve Sinus & Headache

• Aleve-d Sinus & Cold

• Aleve-d Sinus & Headache

• All Day Pain Relief

• All Day Pain Relief Sinus & Co

• All Day Relief

• amlodipine-atorvastatin

• amoxicil-clarithromy-lansopraz

• Anaprox

• Anaprox Ds

• Ansaid

• Arthrotec 50

• atorvastatin

• Biaxin

• Biaxin Xl

• Biaxin Xl Pak

• Caduet

• Caldolor

• Cambia

• Cancidas

• caspofungin

• Cataflam

• Celebrex

• celecoxib

• Child Ibuprofen

• Children's Advil

• Children's Ibu-drops

• Children's Ibuprofen

• Children's Medi-profen

• Children's Motrin

• Children's Profen Ib

• chlorphen-phenyleph-ibuprofen

• chlorphen-pseudoeph-ibuprofen

• cilostazol

• clarithromycin

• Cold & Sinus Pain Relief

• Cold-sinus Relief

• Crixivan

• Daypro

• diclofenac epolamine

• diclofenac potassium

• diclofenac sodium

• diclofenac submicronized

• diclofenac-misoprostol

• didanosine

• Diskets

• Dolophine

• Duexis

• Ec-naprosyn

• etodolac

• ezetimibe-atorvastatin

• ezetimibe-simvastatin

• Feldene

• fenoprofen

• Flanax

• Flector

• flurbiprofen

• fosamprenavir

• Gilotrif

• hydrocodone-ibuprofen

• I-prin

• Ibu-drops

• Ibudone

• ibuprofen

• Ibuprofen Cold

• Ibuprofen Cold-sinus(with Pse)

• Ibuprofen Ib

• Ibuprofen Jr Strength

• ibuprofen lysine (PF)

• Ibuprofen Pm

• ibuprofen-diphenhydramine

• ibuprofen-diphenhydramine HCl

• ibuprofen-famotidine

• ibuprofen-oxycodone

• ibuprofen-phenylephrine HCl

• indinavir

• Indocin

• indomethacin

• indomethacin sodium

• Infant's Ibuprofen

• Infant's Medi-profen

• Infant's Motrin

• Infants Ibu-drops

• Infants Profenib

• Invirase

• Kaletra

• ketoprofen

• ketorolac

• Lexiva

• Lipitor

• Liptruzet

• lopinavir-ritonavir

• Medi-profen

• Mediproxen

• mefenamic acid

• meloxicam

• methadone

• Methadone Intensol

• Methadose

• Midol (naproxen)

• Mobic

• Motrin Ib

• Motrin Pm

• Mycobutin

• Zipsor

• Zocor

• Zorvolex

• Wal-proxen

• Wal-profen Cold-sinus

• Wal-profen

• Vytorin 10-80

• Vytorin 10-40

• Vytorin 10-20

• Vytorin 10-10

• Voltaren-xr

• Vimovo

• Videx Ec

• Videx 4 Gram Pediatric

• Videx 2 Gram Pediatric

• Vicoprofen

• tolmetin

• sulindac

• Sprix

• Solaraze

• Sinus & Cold-d

• simvastatin

• Simcor

• saquinavir mesylate

• rifabutin

• Reprexain

• pseudoephedrine-ibuprofen

• Provil

• Prevpac

• pravastatin

• Pravachol

• Ponstel

• Pletal

• piroxicam

• Pennsaid

• oxaprozin

• omeprazole-clarith-amoxicillin

• Omeclamox-pak

• niacin-simvastatin

• Neoprofen (ibuprofen Lysn)(pf)

• naproxen-pseudoephedrine

• naproxen-esomeprazole

• naproxen sodium

• naproxen

• Naprosyn

• Naprelan Cr

• Nalfon

• nabumetone

Moderate

• Aggressive behavior

• Chronic hepatitis B

• CYp2b6*6/*6 genotype

• Hypercholesterolemia

• Hypertriglyceridemia

• Insomnia

• Kidney disease with likely reduction in GFR

• Osteopenia

• Seizure disorder

Efavirenz

• Severity Level:

  2

• Additional Notes: No fda cat;art preg registry data show no increased risk for major birth defects

Emtricitabine

• Severity Level:

  2

• Additional Notes: Available human data show no increased risk for major malformations.

Tenofovir

• Severity Level:

  2

• Additional Notes: Available human data show no increased risk for major birth defects

Contraindicated

Efavirenz

Cdc does not recommend breastfeeding in hiv-positive women

Cdc does not recommend breastfeeding in hiv-positive women.

General	Excretion Potential	Effect on Infant	Notes
Drug should not be given to breast feeding mothers	Excreted	Not known; no or inclusive data	Cdc does not recommend breastfeeding in hiv-positive women

Emtricitabine

Cdc does not recommend breastfeeding in hiv-positive women

Cdc does not recommend breastfeeding in hiv-positive women.

General	Excretion Potential	Effect on Infant	Notes
Drug should not be given to breast feeding mothers	Excreted	Not known; no or inclusive data	Cdc does not recommend breastfeeding in hiv-positive women.

Precaution Exists

Tenofovir

Limited data suggest no known adverse effects in nursing infant

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Limited data suggest no known adverse effects in nursing infant

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Emtricitabine

Renal- Adhere to manufacturer guidelines for renal impairment and lower CrCL.

Renal-Adjust dosing interval for CrCL<50mL/min. Fixed dose combinations containing tenofovir are not appropriate if dose adjustment is required. Musculoskeletal-Decreases in bone mineral density have been observed. Consider calcium and vitamin D3 supplementation.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	Y	N	N	N	N

BEERS: N     HEDIS: N     STOPP: N

Tenofovir Disoproxil

Renal- Adhere to manufacturer guidelines for renal impairment and lower CrCL.

Renal-Adjust dosing interval for CrCL<50mL/min. Fixed dose combinations containing tenofovir are not appropriate if dose adjustment is required. Musculoskeletal-Decreases in bone mineral density have been observed. Consider calcium and vitamin D3 supplementation.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	Y	Y	N	N	N

BEERS: N     HEDIS: N     STOPP: N

No Known Risk

None

0-9	A-Z
B20	Human immunodeficiency virus [HIv] disease
B97.35	Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere
O98.7	Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium
O98.71	Human immunodeficiency virus [HIv] disease complicating pregnancy
O98.711	Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester
O98.712	Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester
O98.713	Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester
O98.719	Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester
O98.72	Human immunodeficiency virus [HIv] disease complicating childbirth
O98.73	Human immunodeficiency virus [HIv] disease complicating the puerperium
Z21	Asymptomatic human immunodeficiency virus [HIv] infection status