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CEREZYME (IMIGLUCERASE)
- Gaucher's disease
400 unit intravenous solution
- Infuse 2.5 unit/kg over 1-2 hour(s) by intravenous route 3 times per week
Gaucher's disease
- Infuse 2.5 unit/kg over 1-2 hour(s) by intravenous route 3 times per week
- Infuse 60 unit/kg over 1-2 hour(s) by intravenous route every 2 weeks
- None
Contraindicated
- None
Severe
Moderate
- None
- Pulmonary hypertension
Contraindicated
- None
Severe
Moderate
- None
CEREZYME (IMIGLUCERASE)
- Gaucher's disease
- Tachycardia
- Back pain
- Chills
- Diarrhea
- Fatigue
- Fever
More Frequent
Severe
Less Severe
- None
- Abdominal pain with cramps
- Dizziness
- Headache disorder
- Hypotension
- Nausea
- Pruritus of skin
- Skin rash
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Angioedema
- Cyanosis
- Dyspnea
- Urticaria
Less Severe
- Flushing
- Injection site sequelae
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Imiglucerase
Safety and efficacy not established age < 2 years.
- 1 Day – 2 Years
- Safety and efficacy not established age < 2 years.
Imiglucerase
- Severity Level:
C
- Additional Notes: Insufficient data available; limited data suggest teratogenicity risk low
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Imiglucerase
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Gaucher's disease | |
| E75.22 | Gaucher disease |
| 0-9 | A-Z |
|---|---|
| E75.22 | Gaucher disease |
Formulary Reference Tool