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NIFEDIPINE (NIFEDIPINE)
- Prevention of anginal pain from vasospastic angina
- Prevention of anginal pain in coronary artery disease
10 mg capsule
- 1 capsule (10 mg) by oral route 3 times per day
10 mg capsule
- 1 capsule (10 mg) by oral route 3 times per day
20 mg capsule
- 1 capsule (20 mg) by oral route 3 times per day
Prevention of anginal pain from vasospastic angina
- 1 capsule (10 mg) by oral route 3 times per day
- 2 capsules (20 mg) by oral route 4 times per day
- 1 capsule (20 mg) by oral route 3 times per day
- 1 capsule (20 mg) by oral route 4 times per day
- 3 capsules (30 mg) by oral route 4 times per day
Prevention of anginal pain in coronary artery disease
- 1 capsule (10 mg) by oral route 3 times per day
- 2 capsules (20 mg) by oral route 4 times per day
- 1 capsule (20 mg) by oral route 3 times per day
- 1 capsule (20 mg) by oral route 4 times per day
- 3 capsules (30 mg) by oral route 4 times per day
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Belladonna-phenobarbital
- calcium-mag-B complex-D3-hrb61
- carbamazepine
- Carbatrol
- Cerebyx
- Cold & Flu Fighter
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- Epitol
- Equetro
- Fatigue Relief Complex
- fosphenytoin
- isoniazid-rifamp-pyrazinamide
- Luminal
- Mycobutin
- Mysoline
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- primidone
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- St. John's wort
- Tegretol
- Tegretol Xr
- vit C-St. John wort-elder-hb30
- Women's Complex
Contraindicated
- amoxicil-clarithromy-lansopraz
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- clarithromycin
- Dantrium
- dantrolene
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- Ketek
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Prevpac
- Revonto
- telithromycin
Severe
Moderate
- acebutolol
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Astagraf Xl
- atenolol
- atenolol-chlorthalidone
- Betapace
- Betapace Af
- Betimol
- boceprevir
- brimonidine-timolol
- Bystolic
- cimetidine
- Combigan
- Corgard
- Corzide
- Cosopt
- Cosopt Pf
- dextromethorphan-quinidine
- Digox
- digoxin
- dorzolamide-timolol
- dorzolamide-timolol (PF)
- dronedarone
- Dutoprol
- Heartburn Relief
- Hecoria
- Incivek
- Inderal La
- Inderal Xl
- Innopran Xl
- Istalol
- ketoconazole
- labetalol
- Lanoxin
- Lanoxin Pediatric
- Lopressor
- Lopressor Hct
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Multaq
- nadolol
- nadolol-bendroflumethiazide
- nebivolol
- Nuedexta
- pindolol
- Prograf
- propranolol
- propranolol-hydrochlorothiazid
- quinidine gluconate
- quinidine sulfate
- Sectral
- Sorine
- sotalol
- Sotalol Af
- tacrolimus
- Tagamet Hb
- telaprevir
- Tenoretic 100
- Tenoretic 50
- Tenormin
- timolol
- timolol maleate
- timolol maleate (PF)
- Timoptic
- Timoptic Ocudose (pf)
- Timoptic-xe
- Toprol Xl
- Trandate
- Victrelis
- Acute coronary syndrome
- Acute myocardial infarction
Contraindicated
- Chronic idiopathic constipation
- Hypotension
- Myasthenia gravis
- Severe aortic valve stenosis
- Severe chronic heart failure
Severe
Moderate
- Hepatic cirrhosis
- Kidney disease with reduction in GFR
- Peripheral edema
- Porphyria
NIFEDIPINE (NIFEDIPINE)
- Prevention of anginal pain from vasospastic angina
- Prevention of anginal pain in coronary artery disease
- None
- Dizziness
- Flushing
- General weakness
- Headache disorder
- Nausea
- Peripheral edema
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Hypotension
- Constipation
- Cough
- Cramps in legs
- Diarrhea
- Dyspnea
- Erectile dysfunction
- Fever
- Hyperhidrosis
- Joint stiffness
- Mood changes
- Nervousness
- Palpitations
- Paresthesia
- Pruritus of skin
- Rhinitis
- Sleep disorder
- Urticaria
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute eruptions of skin
- Acute myocardial infarction
- Anaphylaxis
- Anemia
- Angioedema
- Arthralgias
- Atrial fibrillation
- Bradycardia
- Cellulitis
- Chronic heart failure
- Exfoliative dermatitis
- Gingival hyperplasia
- Hepatitis
- Jaundice
- Kidney stone
- Leukopenia
- Purpura
- Severe hypotension
- Skin rash
- Stevens-johnson syndrome
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Transient blindness
Less Severe
- Acute confusion
- Arthritis
- Breast engorgement
- Chills
- Depression
- Drowsy
- Dyspepsia
- Dysphagia
- Dysuria
- Eosinophilia
- Eructation
- Erythromelalgia
- Esophagitis
- Facial edema
- Flatulence
- Gout
- Gynecomastia
- Hyperglycemia
- Hypertonia
- Hypesthesia
- Insomnia
- Libido changes
- Lymphadenopathy
- Muscle weakness
- Myalgias
- Nocturia
- Pharyngitis
- Phlebitis
- Phototoxicity
- Polyuria
- Rales
- Stridor
- Symptoms of anxiety
- Syncope
- Telangiectasia
- Visual changes
- Weight loss
- Xerostomia
Contraindicated
None
Severe Precaution
Nifedipine
No dosing guidelines available age <1 year. Not recommended per manufacturer.
Use the lowest effective dose; risk of severe hypotension. Caution with CNS injury, risk of stroke, seizure.
- 1 Day – 364 Days
- No dosing guidelines available age <1 year. Not recommended per manufacturer.
- 1 Years – 18 Years
- No dosing guidelines available age <1 year. Not recommended per manufacturer.
Nifedipine (Short Acting)
No dosing guidelines available age <1 year. Not recommended per manufacturer.
Use the lowest effective dose; risk of severe hypotension. Caution with CNS injury, risk of stroke, seizure.
- 1 Day – 364 Days
- Use the lowest effective dose; risk of severe hypotension. Caution with CNS injury, risk of stroke, seizure.
- 1 Years – 18 Years
- Use the lowest effective dose; risk of severe hypotension. Caution with CNS injury, risk of stroke, seizure.
Management or Monitoring Precaution
None
Nifedipine
- Severity Level:
C
- Additional Notes: Teratogenic in animals at at doses 5 to 50 times mrhd
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Nifedipine
Amount excreted is negligible, adverse effect potential for infant unknown
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Amount excreted is negligible, adverse effect potential for infant unknown |
Contraindicated
Nifedipine (short Acting)
General-Sustained release products are preferred. Risks for hypotension, edema and constipation. Decreased clearance and higher AUC in the elderly. Generally not recommended. Cardiovascular-Risk of myocardial ischemia.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: Y HEDIS: Y STOPP: Y
Precaution Exists
None
No Known Risk
None
- None
| Prevention of anginal pain from vasospastic angina | |
| I20.1 | Angina pectoris with documented spasm |
| I25.111 | Atherosclerotic heart disease of native coronary artery with angina pectoris with documented spasm |
| I25.701 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris with documented spasm |
| I25.711 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.721 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.731 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.751 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.761 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.791 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris with documented spasm |
| Prevention of anginal pain in coronary artery disease | |
| I20 | Angina pectoris |
| I20.9 | Angina pectoris, unspecified |
| I25.11 | Atherosclerotic heart disease of native coronary artery with angina pectoris |
| I25.118 | Atherosclerotic heart disease of native coronary artery with other forms of angina pectoris |
| I25.119 | Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris |
| I25.7 | Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris |
| I25.70 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris |
| I25.708 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with other forms of angina pectoris |
| I25.709 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unspecified angina pectoris |
| I25.71 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris |
| I25.718 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.719 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.72 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris |
| I25.728 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.729 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.73 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris |
| I25.738 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.739 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.75 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris |
| I25.758 | Atherosclerosis of native coronary artery of transplanted heart with other forms of angina pectoris |
| I25.759 | Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris |
| I25.76 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris |
| I25.768 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with other forms of angina pectoris |
| I25.769 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unspecified angina pectoris |
| I25.79 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris |
| I25.798 | Atherosclerosis of other coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.799 | Atherosclerosis of other coronary artery bypass graft(s) with unspecified angina pectoris |
| 0-9 | A-Z |
|---|---|
| I20 | Angina pectoris |
| I20.1 | Angina pectoris with documented spasm |
| I20.9 | Angina pectoris, unspecified |
| I25.11 | Atherosclerotic heart disease of native coronary artery with angina pectoris |
| I25.111 | Atherosclerotic heart disease of native coronary artery with angina pectoris with documented spasm |
| I25.118 | Atherosclerotic heart disease of native coronary artery with other forms of angina pectoris |
| I25.119 | Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris |
| I25.7 | Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris |
| I25.70 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris |
| I25.701 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris with documented spasm |
| I25.708 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with other forms of angina pectoris |
| I25.709 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unspecified angina pectoris |
| I25.71 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris |
| I25.711 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.718 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.719 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.72 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris |
| I25.721 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.728 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.729 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.73 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris |
| I25.731 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.738 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.739 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.75 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris |
| I25.751 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.758 | Atherosclerosis of native coronary artery of transplanted heart with other forms of angina pectoris |
| I25.759 | Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris |
| I25.76 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris |
| I25.761 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.768 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with other forms of angina pectoris |
| I25.769 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unspecified angina pectoris |
| I25.79 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris |
| I25.791 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.798 | Atherosclerosis of other coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.799 | Atherosclerosis of other coronary artery bypass graft(s) with unspecified angina pectoris |
Formulary Reference Tool