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EPIDUO (ADAPALENE/BENZOYL PEROXIDE)
- Acne vulgaris
0.1 %-2.5 % topical gel with pump
- Apply a thin layer to the affected area(s) of the face and/or upper trunk after washing by topical route once daily
adapalene 0.1 %-benzoyl peroxide 2.5 % topical gel with pump
- Apply a thin layer to the affected area(s) of the face and/or upper trunk after washing by topical route once daily
adapalene 0.3 %-benzoyl peroxide 2.5 % topical gel with pump
- Apply a thin layer to the affected area(s) of the face and/or upper trunk after washing by topical route once daily
Acne vulgaris
- Apply a pea-sized amount by topical route once daily to cover areas of face with thin layer after washing avoiding the eyes and lips
- Apply a thin layer to the affected area(s) of the face and/or upper trunk after washing by topical route once daily
- None
Contraindicated
- None
Severe
Moderate
- None
- Pregnancy
Contraindicated
- Exfoliative dermatitis
- Skin photosensitivity
Severe
Moderate
- None
EPIDUO (ADAPALENE/BENZOYL PEROXIDE)
- Acne vulgaris
- Erythema
- Pruritus of skin
- Skin scaling
- Stinging of skin
- Dry skin
More Frequent
Severe
Less Severe
- Skin irritation
- Abnormal desquamation
- Dry skin
- Erythema
- Sensation of warmth
- Skin irritation
- Stinging of skin
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Dermatitis due to topical drug
- Dyspnea
- Facial edema
- Hypersensitivity drug reaction
- Periorbital edema
- Pharyngeal edema
- Pruritus of skin
- Skin rash
- Syncope
- Throat constriction
- Urticaria
Less Severe
- Dyschromia
- Skin photosensitivity
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Adapalene (0.1%)
Safety and efficacy not established age < 9 years.
- 1 Day – 9 Years
- Safety and efficacy not established age < 9 years.
Adapalene
- Severity Level:
1
- Additional Notes: Fda c; retinoid-like activity; theoretical concern of dev tox
Benzoyl Peroxide
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Adapalene
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
Benzoyl Peroxide
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Acne vulgaris | |
| L70.0 | Acne vulgaris |
| 0-9 | A-Z |
|---|---|
| L70.0 | Acne vulgaris |
Formulary Reference Tool