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Drug overview for CASTOR OIL (castor oil):
Generic name: CASTOR OIL (KAS/tor)
Drug class: Stimulant Laxatives
Therapeutic class: Gastrointestinal Therapy Agents
Castor oil, a stimulant laxative, is a fixed oil obtained from the seeds of Ricinus communis.
No enhanced Uses information available for this drug.
Generic name: CASTOR OIL (KAS/tor)
Drug class: Stimulant Laxatives
Therapeutic class: Gastrointestinal Therapy Agents
Castor oil, a stimulant laxative, is a fixed oil obtained from the seeds of Ricinus communis.
No enhanced Uses information available for this drug.
DRUG IMAGES
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The following indications for CASTOR OIL (castor oil) have been approved by the FDA:
Indications:
Constipation
Professional Synonyms:
None.
Indications:
Constipation
Professional Synonyms:
None.
The following dosing information is available for CASTOR OIL (castor oil):
The usual adult dose of castor oil for constipation is 15 mL; however, castor oil usually should be reserved for total colonic evacuation, such as prior to surgery or radiologic, sigmoidoscopic, or proctoscopic procedures. For these purposes, the usual dose of castor oil is 15-60 mL for adults and children 12 years of age and older, 5-15 mL for children 2-11 years of age, or 1-5 mL for children younger than 2 years of age, administered as a single dose about 16 hours before the surgery or procedure. To prepare for colonic surgery or radiologic, sigmoidoscopic, or proctoscopic procedures, the patient should receive a residue-free diet one day before the surgery or procedure and a cleansing rectal enema (e.g., tap water, soap suds, saline laxative, bisacodyl) on the day of the examination. Additionally, standardized senna fruit extract may be administered 4 hours after castor oil.
Castor oil is administered orally. Emulsions or aromatic preparations somewhat mask the disagreeable taste of castor oil. Containers of castor oil emulsion should be shaken before using, and the emulsion may be mixed with 120-240 mL of water, milk, fruit juice, or soft drink before administration.
No dosing information available.
No generic dosing information available.
The following drug interaction information is available for CASTOR OIL (castor oil):
There are 0 contraindications.
There are 2 severe interactions.
These drug interactions can produce serious consequences in most patients. Actions required for severe interactions include, but are not limited to, discontinuing one or both agents, adjusting dosage, altering administration scheduling, and providing additional patient monitoring. Review the full interaction monograph for more information.
| Drug Interaction | Drug Names |
|---|---|
| Trofinetide/Laxatives SEVERITY LEVEL: 2-Severe Interaction: Action is required to reduce the risk of severe adverse interaction. MECHANISM OF ACTION: Trofinetide commonly causes diarrhea of mild to moderate severity. Laxatives may increase the incidence or severity of diarrhea.(1) CLINICAL EFFECTS: Concurrent use of laxatives with trofinetide may increase the risk of severe diarrhea.(1) PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: Patients should stop laxatives before starting trofinetide. If diarrhea occurs, consider anti-diarrheal treatment and monitor hydration status. If severe diarrhea or dehydration occurs, interrupt, reduce dose, or discontinue trofinetide.(1) DISCUSSION: In clinical trials, 85% of patients on trofinetide developed diarrhea. Concurrent use of laxatives may increase this risk.(1) |
DAYBUE |
| Tenapanor/Laxatives; Stool Softeners SEVERITY LEVEL: 2-Severe Interaction: Action is required to reduce the risk of severe adverse interaction. MECHANISM OF ACTION: Tenapanor commonly causes diarrhea of mild to moderate severity. Laxatives and stool softeners may increase the incidence or severity of diarrhea.(1) CLINICAL EFFECTS: Concurrent use of laxatives or stool softeners with tenapanor may increase the risk of severe diarrhea.(1) PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: The US manufacturer of tenapanor states that patients should be instructed to avoid stool softeners and laxatives with tenapanor. If severe diarrhea occurs, tenapanor should be discontinued.(1) DISCUSSION: In clinical trials, 43-53% of CKD patients on dialysis treated with tenapanor developed diarrhea. Diarrhea usually occurred soon after treatment initiation and was severe in 5% of patients.(1) |
XPHOZAH |
There are 0 moderate interactions.
The following contraindication information is available for CASTOR OIL (castor oil):
Drug contraindication overview.
No enhanced Contraindications information available for this drug.
No enhanced Contraindications information available for this drug.
There are 3 contraindications.
Absolute contraindication.
| Contraindication List |
|---|
| Appendicitis |
| Gastrointestinal obstruction |
| Pregnancy |
There are 0 severe contraindications.
There are 0 moderate contraindications.
The following adverse reaction information is available for CASTOR OIL (castor oil):
Adverse reaction overview.
No enhanced Common Adverse Effects information available for this drug.
No enhanced Common Adverse Effects information available for this drug.
There are 4 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. |
Dehydration |
| Rare/Very Rare |
|---|
|
Disorder of electrolytes Syncope Ulceration of colon |
There are 7 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. |
Abdominal pain with cramps Diarrhea Dizziness Eructation Headache disorder Nausea |
| Rare/Very Rare |
|---|
|
Urine discoloration |
The following precautions are available for CASTOR OIL (castor oil):
No enhanced Pediatric Use information available for this drug.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
No enhanced Pregnancy information available for this drug.
No enhanced Lactation information available for this drug.
No enhanced Geriatric Use information available for this drug.
The following prioritized warning is available for CASTOR OIL (castor oil):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for CASTOR OIL (castor oil)'s list of indications:
| Constipation | |
| K59.0 | Constipation |
| K59.00 | Constipation, unspecified |
| K59.01 | Slow transit constipation |
| K59.03 | Drug induced constipation |
| K59.04 | Chronic idiopathic constipation |
| K59.09 | Other constipation |
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