BYSTOLIC (NEBIVOLOL HCL)
- Hypertension
10 mg tablet
- 1 tablet (10 mg) by oral route once daily
2.5 mg tablet
- 2 tablets (5 mg) by oral route once daily
20 mg tablet
- 1 tablet (20 mg) by oral route once daily
5 mg tablet
- 1 tablet (5 mg) by oral route once daily
Hypertension
- 2 tablets (5 mg) by oral route once daily
- 1 tablet (5 mg) by oral route once daily
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 2 tablets (40 mg) by oral route once daily
- None
Contraindicated
- Catapres
- Catapres-tts-1
- Catapres-tts-2
- Catapres-tts-3
- clonidine
- clonidine (PF)
- clonidine-chlorthalidone
- Clorpres
- Corlopam
- Duraclon (pf)
- fenoldopam
- fingolimod
- Gilenya
- Kapvay
Severe
Moderate
- Adalat Cc
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Afeditab Cr
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- amiodarone
- amiodarone in dextrose,iso-osm
- Anaprox
- Anaprox Ds
- Ansaid
- Calan
- Calan Sr
- Caldolor
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Cordarone
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- dronedarone
- Duexis
- Ec-naprosyn
- Ez Use Joint-tunnel-trigger
- Feldene
- Flanax
- fluoxetine
- flurbiprofen
- hydrocodone-ibuprofen
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- isoniazid-rifamp-pyrazinamide
- Lamisil
- lidocaine (PF)
- lidocaine in D5W (PF)
- Matzim La
- Medi-profen
- Mediproxen
- meloxicam
- Midol (naproxen)
- mirabegron
- Mobic
- Motrin Ib
- Motrin Pm
- Multaq
- Mycobutin
- Myrbetriq
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- Neoprofen (ibuprofen Lysn)(pf)
- Nexterone
- Nifedical Xl
- nifedipine
- olanzapine-fluoxetine
- Pacerone
- piroxicam
- Priftin
- Procardia
- Procardia Xl
- Provil
- Prozac
- Prozac Weekly
- pseudoephedrine-ibuprofen
- Reprexain
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- Sarafem
- Sinus & Cold-d
- sulindac
- Symbyax
- Tarka
- Taztia Xt
- terbinafine
- Tiazac
- trandolapril-verapamil
- triamcinolone-lidocaine
- verapamil
- Verelan
- Verelan Pm
- Vicoprofen
- Vimovo
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Xylocaine (cardiac) (pf)
- Acute decompensated heart failure
- Cardiogenic shock
- Complete atrioventricular block
- Pregnancy
- Second degree atrioventricular heart block
- Severe hepatic disease
Contraindicated
- Bradycardia
- Bronchospastic pulmonary disease
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Chronic kidney disease stage 5 (failure) GFr<15 ml/min
- Disease of liver
- Peripheral vascular disease
- Sick sinus syndrome
Severe
Moderate
- Diabetes mellitus
- Hypoglycemic disorder
- Kidney disease with likely reduction in GFR
BYSTOLIC (NEBIVOLOL HCL)
- Hypertension
- None
- Fatigue
- Headache disorder
More Frequent
Severe
Less Severe
- Bradycardia
- Chest pain
- Dyspnea
- Diarrhea
- Dizziness
- Insomnia
- Nausea
- Peripheral edema
- Skin rash
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Acute renal failure
- Angioedema
- Atrioventricular block
- Bronchospastic pulmonary disease
- Hypersensitivity angiitis
- Hypotension
- Peripheral ischemia
- Peripheral vasoconstriction
- Psoriasis
- Pulmonary edema
- Syncope
- Thrombocytopenic disorder
- Urticaria
Less Severe
- Acute abdominal pain
- Drowsy
- Erectile dysfunction
- General weakness
- Hypercholesterolemia
- Paresthesia
- Pruritus of skin
- Raynaud's phenomenon
- Vertigo
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Nebivolol
No pediatric safety studies. Concerns of potential developmental toxicity.
- 1 Day – 18 Years
- No pediatric safety studies. Concerns of potential developmental toxicity.
Nebivolol
- Severity Level:
1
- Additional Notes: Beta blockers w/out isa may cause intrauterine growth restriction
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Nebivolol
Not recommended by manufacturer
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Not recommended by manufacturer |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Nebivolol
Renal-Drug clearance may be affected by CrCL<50 mL/min. Particularly consider lower starting doses and slower dose titration with CrCL<30 mL/min to minimize hypotension, dizziness and falls. Endocrine-Beta-blocker may mask the symptoms of hypoglycemia and thus require more frequent monitoring in some patients with diabetes.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | N | N | N | N | Y |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
Hypertension | |
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |
0-9 | A-Z |
---|---|
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |