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ENDOMETRIN (PROGESTERONE,MICRONIZED)
- Corpus luteum insufficiency syndrome
100 mg vaginal insert
- Insert 1 vaginal insert (100 mg) by vaginal route 2 times per day
Corpus luteum insufficiency syndrome
- Insert 1 vaginal insert (100 mg) by vaginal route 3 times per day
- Insert 1 vaginal insert (100 mg) by vaginal route 2 times per day
- Insert 1 vaginal insert (100 mg) by vaginal route 3 times per day for10 weeks
- Insert 1 vaginal insert (100 mg) by vaginal route 2 times per day for10 weeks
- None
Contraindicated
- None
Severe
Moderate
- None
- Carcinoma of breast
- Cerebrovascular accident
- Disease of liver
- Malignant neoplasm of liver
- Porphyria
- Predisposition to thrombosis
- Pulmonary thromboembolism
- Thromboembolic disorder
- Thrombophlebitis
Contraindicated
- Hypertension
Severe
Moderate
- Asthma
- Chronic heart failure
- Depression
- Diabetes mellitus
- Hyperlipidemia
- Kidney disease with reduction in GFR
- Migraine
- Seizure disorder
ENDOMETRIN (PROGESTERONE,MICRONIZED)
- Corpus luteum insufficiency syndrome
- Abdominal distension
- Abnormal vaginal bleeding
- Irregular menstrual periods
- Appetite changes
- Edema
- Fatigue
- Headache disorder
- Myalgias
- Vaginitis
- Weight loss
More Frequent
Severe
Less Severe
- None
- Dizziness
- Dyspepsia
- Hypertonia
- Irritability
- Vaginal discharge
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Anaphylaxis
- Angioedema
- Back pain
- Chest pain
- Cystitis
- Depression
- Ectopic pregnancy
- Erythema multiforme
- Erythema nodosum
- Galactorrhea not associated with childbirth
- Hepatitis
- Hypersensitivity drug reaction
- Malignant neoplasm of the ovary
- Menorrhagia
- Obstructive hyperbilirubinemia
- Optic neuritis
- Ovarian cyst
- Pancreatitis
- Pruritus of skin
- Pulmonary thromboembolism
- Retinal thrombosis
- Skin rash
- Thromboembolic disorder
- Thrombophlebitis
Less Severe
- Acne vulgaris
- Alopecia
- Amenorrhea
- Body fluid retention
- Cervical discharge
- Chloasma
- Constipation
- Drowsy
- Erosion of cervix
- Fever
- Hirsutism
- Hyperglycemia
- Insomnia
- Limb pain
- Mastalgia
- Migraine
- Nausea
- Nervousness
- Urticaria
- Weight gain
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Progesterone
Safety and efficacy in pediatrics have not been established.
- 1 Day – 18 Years
- Safety and efficacy in pediatrics have not been established.
Progesterone
- Severity Level:
B
- Additional Notes: Insufficient human data; animal data do not suggest dev tox
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Progesterone
Data suggest low amount excreted with no adverse effects on infants
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Data suggest low amount excreted with no adverse effects on infants |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Corpus luteum insufficiency syndrome | |
| E28.39 | Other primary ovarian failure |
| E28.8 | Other ovarian dysfunction |
| 0-9 | A-Z |
|---|---|
| E28.39 | Other primary ovarian failure |
| E28.8 | Other ovarian dysfunction |
Formulary Reference Tool