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MOLINDONE HCL (molindone HCl)
- Schizophrenia
molindone 10 mg tablet
- 1 tablet (10 mg) by oral route 3 times per day
molindone 25 mg tablet
- 1 tablet (25 mg) by oral route 3 times per day
molindone 5 mg tablet
- 1 tablet (5 mg) by oral route 3 times per day
Schizophrenia
- 1 tablet (5 mg) by oral route 3 times per day
- 1 tablet (5 mg) by oral route 4 times per day
- 2 tablets (10 mg) by oral route 4 times per day
- 1 tablet (10 mg) by oral route 4 times per day
- 2 tablets (10 mg) by oral route 3 times per day
- 1 tablet (10 mg) by oral route 3 times per day
- 3 tablets (15 mg) by oral route 3 times per day
- 3 tablets (15 mg) by oral route 4 times per day
- 2 tablets (20 mg) by oral route 3 times per day
- 2 tablets (20 mg) by oral route 4 times per day
- 1 tablet (25 mg) by oral route 3 times per day
- 1 tablet (25 mg) by oral route 4 times per day
- 2 tablets (50 mg) by oral route 3 times per day
- 2 tablets (50 mg) by oral route 4 times per day
- one-half tablet (12.5 mg) by oral route 4 times per day
- one-half tablet (12.5 mg) by oral route 3 times per day
- metoclopramide HCl
- Metozolv Odt
- Reglan
Contraindicated
- Apokyn
- apomorphine
- cabergoline
- carbidopa-levodopa
- carbidopa-levodopa-entacapone
- Comtan
- entacapone
- Mirapex
- Mirapex Er
- pramipexole
- Requip
- Requip Xl
- ropinirole
- Sinemet
- Sinemet Cr
- Stalevo 100
- Stalevo 125
- Stalevo 150
- Stalevo 200
- Stalevo 50
- Stalevo 75
Severe
Moderate
- Alagesic Lq
- amobarbital
- Amytal
- Aplenzin
- Ascomp With Codeine
- Belladonna-phenobarbital
- Bupap
- Buproban
- bupropion HBr
- bupropion HCl
- butabarbital
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-acetaminop-caf-cod
- butalbital-acetaminophen
- butalbital-acetaminophen-caff
- butalbital-aspirin-caffeine
- Butisol
- Capacet
- codeine-butalbital-ASA-caff
- Donnatal
- Esgic
- Fioricet
- Fioricet With Codeine
- Fiorinal
- Fiorinal-codeine #3
- Forfivo Xl
- Luminal
- Margesic
- Marten-tab
- Mysoline
- Nembutal Sodium
- pentobarbital sodium
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- primidone
- secobarbital sodium
- Seconal Sodium
- Tencon
- Wellbutrin
- Wellbutrin Sr
- Wellbutrin Xl
- Zebutal
- Zyban
- Agranulocytosis
- Coma
- Drug-induced CNS depression
- Neuroleptic malignant syndrome
Contraindicated
- Carcinoma of breast
- Respiratory depression
- Senile dementia
- Tardive dyskinesia
Severe
Moderate
- Disease of liver
- Gastrointestinal obstruction
- Hyperprolactinemia
- Leukopenia
- Neoplasm of brain
- Neutropenic disorder
- Parkinsonism
- Seizure disorder
MOLINDONE HCL (molindone HCl)
- Schizophrenia
- Akathisia
- Extrapyramidal disease
- Parkinsonism
- Tardive dyskinesia
- Blurred vision
- Constipation
- Decreased sweating
- Drowsy
- Dysuria
- Headache disorder
- Nasal congestion
- Nausea
- Xerostomia
More Frequent
Severe
Less Severe
- Depression
- Abnormal sexual function
- Erectile dysfunction
- Galactorrhea not associated with childbirth
- Gynecomastia
- Irregular menstrual periods
- Orthostatic hypotension
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Accidental fall
- Acquired dystonia
- Agranulocytosis
- Allergic dermatitis
- Heat stroke
- Hepatitis
- Jaundice
- Leukopenia
- Neuroleptic malignant syndrome
- Neutropenic disorder
- Seizure disorder
- Skin rash
- Tachycardia
- Urinary retention
Less Severe
- Euphoria
- Hyperkinesis
Contraindicated
None
Severe Precaution
Molindone
Not recommended by manufacturer. No safety and efficacy age <12 years.
- 1 Day – 12 Years
- Not recommended by manufacturer. No safety and efficacy age <12 years.
Management or Monitoring Precaution
None
Molindone
- Severity Level:
2
- Additional Notes: No fda category; neonate complications ( resp,gi,cns) w/exposure in 3rd trim
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Molindone
Insuff. Data avail; molecular wt low enough for possible breastmilk excretion.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insuff. Data avail; molecular wt low enough for possible breastmilk excretion. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Molindone
Neuro/Psych-Higher risk of tardive dyskinesia in the elderly. Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Increased risk of death in senile dementia. Maximum of 10mg/day. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Urogenital-Best avoided in patients with urinary retention from any cause.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.
| Schizophrenia | |
| F20 | Schizophrenia |
| F20.0 | Paranoid schizophrenia |
| F20.1 | Disorganized schizophrenia |
| F20.2 | Catatonic schizophrenia |
| F20.3 | Undifferentiated schizophrenia |
| F20.5 | Residual schizophrenia |
| F20.8 | Other schizophrenia |
| F20.81 | Schizophreniform disorder |
| F20.89 | Other schizophrenia |
| F20.9 | Schizophrenia, unspecified |
| 0-9 | A-Z |
|---|---|
| F20 | Schizophrenia |
| F20.0 | Paranoid schizophrenia |
| F20.1 | Disorganized schizophrenia |
| F20.2 | Catatonic schizophrenia |
| F20.3 | Undifferentiated schizophrenia |
| F20.5 | Residual schizophrenia |
| F20.8 | Other schizophrenia |
| F20.81 | Schizophreniform disorder |
| F20.89 | Other schizophrenia |
| F20.9 | Schizophrenia, unspecified |
Formulary Reference Tool