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GONAL-F (FOLLITROPIN ALFA, RECOMB)
- Follicle stimulation for assisted fertilization
- Hypogonadotropic hypogonadism
- Infertility associated with anovulation
1,050 unit subcutaneous solution
- Inject 225 unit by subcutaneous route once daily
450 unit subcutaneous solution
- Inject 150 unit by subcutaneous route once daily
Follicle stimulation for assisted fertilization
- Inject 150 unit by subcutaneous route once daily
- Inject 300 unit by subcutaneous route once daily
- Inject 450 unit by subcutaneous route once daily
- Inject 225 unit by subcutaneous route once daily
- Inject 150 unit by subcutaneous route once daily for up to 10 days per cycle
- Inject 225 unit by subcutaneous route once daily for up to 10 days per cycle
- Inject 300 unit by subcutaneous route once daily for up to 10 days per cycle
- Inject 450 unit by subcutaneous route once daily for up to 10 days
Hypogonadotropic hypogonadism
- Inject 150 unit by subcutaneous route 3 times per week
- Inject 300 unit by subcutaneous route 3 times per week
Infertility associated with anovulation
- Inject 150 unit by subcutaneous route once daily
- Inject 300 unit by subcutaneous route once daily
- Inject 450 unit by subcutaneous route once daily
- Inject 225 unit by subcutaneous route once daily
- Inject 150 unit by subcutaneous route once daily for up to 10 days per cycle
- Inject 225 unit by subcutaneous route once daily for up to 10 days per cycle
- Inject 300 unit by subcutaneous route once daily for up to 10 days per cycle
- Inject 450 unit by subcutaneous route once daily for up to 10 days
- None
Contraindicated
- None
Severe
Moderate
- None
- Estrogen-dependent neoplasm
- Hormone receptor positive breast cancer
- Malignant neoplasm of the ovary
- Malignant neoplasm of the uterus
- Malignant tumor of testis
- Ovarian hyperstimulation syndrome
- Pituitary neoplasm
- Pregnancy
- Tumor of hypothalamus
Contraindicated
- Abnormal uterine bleeding
- Acute respiratory distress syndrome
- Atelectasis
- Severe adrenal insufficiency
- Thromboembolic disorder
- Thrombophilia
- Torsion of ovary
- Untreated hypothyroidism
Severe
Moderate
- Morbid obesity
GONAL-F (FOLLITROPIN ALFA, RECOMB)
- Follicle stimulation for assisted fertilization
- Hypogonadotropic hypogonadism
- Infertility associated with anovulation
- Ovarian cyst
- Ovarian enlargement
- Ovarian hyperstimulation syndrome
- Abdominal distension
- Abnormal vaginal bleeding
- Acne vulgaris
- Acute abdominal pain
- Diarrhea
- Flatulence
- Flu-like symptoms
- Mastalgia
- Mood changes
- Nausea
- Pelvic pain
- Pharyngitis
- Sinusitis
- Upper respiratory infection
More Frequent
Severe
Less Severe
- Hypotension
- Migraine
- Anorexia
- Candidiasis
- Chest pain
- Dizziness
- Drowsy
- Dysmenorrhea
- Dyspepsia
- Dysplasia of cervix
- Injection site sequelae
- Nervousness
- Palpitations
- Polydipsia
- Pruritus of skin
- Vaginal discharge
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute respiratory distress syndrome
- Arterial thrombosis
- Asthma exacerbation
- Cerebrovascular accident
- Pulmonary thromboembolism
- Thromboembolic disorder
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Follicle Stimulating Hormones
Safety and efficacy not established. No relevant indication for pediatrics.
- 1 Day – 18 Years
- Safety and efficacy not established. No relevant indication for pediatrics.
Follitropins
- Severity Level:
X
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Follitropins
Excretion unlikely due to high mw; questionable oral absorption by infant.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Excretion unlikely due to high mw; questionable oral absorption by infant. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Follicle stimulation for assisted fertilization | |
| Z31.83 | Encounter for assisted reproductive fertility procedure cycle |
| Z31.89 | Encounter for other procreative management |
| Hypogonadotropic hypogonadism | |
| E23.0 | Hypopituitarism |
| Infertility associated with anovulation | |
| N97.0 | Female infertility associated with anovulation |
| 0-9 | A-Z |
|---|---|
| E23.0 | Hypopituitarism |
| N97.0 | Female infertility associated with anovulation |
| Z31.83 | Encounter for assisted reproductive fertility procedure cycle |
| Z31.89 | Encounter for other procreative management |
Formulary Reference Tool