Cetrotide

Drug overview for CETROTIDE (cetrorelix acetate):

Generic name: CETRORELIX ACETATE (SE-troe-REL-ix)
Drug class: LHrH(GNrH) Antagonist, Pituitary Suppressant Agents
Therapeutic class: Endocrine

Cetrorelix acetate, a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH), is a GnRH antagonist.

No enhanced Uses information available for this drug.

DRUG IMAGES

CETROTIDE 0.25 MG VIAL

The following indications for CETROTIDE (cetrorelix acetate) have been approved by the FDA:

Indications:
Prevention of luteinizing hormone surge when undergoing controlled ovarian hyperstimulation

Professional Synonyms:
Prevention of LH surge in COH
Prophylaxis of luteinizing hormone surge when undergoing controlled ovarian hyperstimulation

Dosing information for CETROTIDE
DRUG LABEL	DOSING TYPE	DOSING INSTRUCTIONS
CETROTIDE 0.25 MG VIAL	Maintenance	Adults inject 0.25 mg by subcutaneous route once daily

Generic dosing information for CETRORELIX ACETATE
DRUG LABEL	DOSING TYPE	DOSING INSTRUCTIONS
CETRORELIX ACETATE 0.25 MG VL	Maintenance	Adults inject 0.25 mg by subcutaneous route once daily

Contraindication List
Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
Chronic kidney disease stage 5 (failure) GFr<15 ml/min
Lactation
Pregnancy

The following adverse reaction information is available for CETROTIDE (cetrorelix acetate):

Overview
Severe
Less Severe

Adverse reaction overview.

Adverse effects occurring in 1% or more of patients receiving cetrorelix include ovarian hyperstimulation syndrome, nausea, and headache.

There are 3 severe adverse reactions.

More Frequent	Less Frequent
None.	Ovarian hyperstimulation syndrome

Rare/Very Rare
Anaphylaxis Hypersensitivity drug reaction

There are 3 less severe adverse reactions.

More Frequent	Less Frequent
None.	None.

Rare/Very Rare
Headache disorder Injection site sequelae Nausea

The following precautions are available for CETROTIDE (cetrorelix acetate):

Pediatric
Pregnant
Lactation
Geriatric

Not indicated.

Contraindicated

None

Severe Precaution

None

Management or Monitoring Precaution

None

Category X. (See Users Guide.) May result in fetal loss secondary to antigonadotropic properties. (See Cautions: Contraindications and also Warnings: Fetal/Neonatal Morbidity and Mortality.)

It is not known whether cetrorelix is distributed in milk; use in nursing women is not recommended.

Not indicated for use in geriatric adults 65 years of age and older.

Prevention of LH surge in ovarian hyperstimulation
Z31.83	Encounter for assisted reproductive fertility procedure cycle
Z31.89	Encounter for other procreative management