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CARDENE I.V. (NICARDIPINE HCL)
- Hypertension
25 mg/10 mL intravenous solution
- Dosage information is not available
25 mg/10 mL intravenous solution
- Dosage information is not available
nicardipine 25 mg/10 mL intravenous solution
- Dosage information is not available
Cardene 25 mg/10 mL intravenous solution
- Dosage information is not available
Hypertension
- Infuse 3 mg/hour by continuous infusion route as needed to maintain desired blood pressure
- Infuse 5 mg/hour by continuous infusion route as needed to maintain desired blood pressure
- Infuse 0.5 mg/hour by continuous infusion route as needed to maintaindesired blood pressure
- Infuse 1.2 mg/hour by continuous infusion route as needed to maintaindesired blood pressure
- Infuse 2.2 mg/hour by continuous infusion route as needed to maintaindesired blood pressure
- Infuse 15 mg/hour by continuous infusion route as needed to maintain desired blood pressure
- None
Contraindicated
- amoxicil-clarithromy-lansopraz
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- clarithromycin
- Dantrium
- dantrolene
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- Ketek
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Prevpac
- Revonto
- telithromycin
Severe
Moderate
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Astagraf Xl
- boceprevir
- cimetidine
- cyclosporine
- cyclosporine modified
- Digox
- digoxin
- Gengraf
- Heartburn Relief
- Hecoria
- Incivek
- ketoconazole
- Lanoxin
- Lanoxin Pediatric
- Neoral
- Prograf
- Rapamune
- Sandimmune
- sirolimus
- tacrolimus
- Tagamet Hb
- telaprevir
- temsirolimus
- Torisel
- Victrelis
- Severe aortic valve stenosis
Contraindicated
- Acute cerebral infarction
- Chronic heart failure
- Chronic idiopathic constipation
- Disease of liver
- Hypotension
- Intracerebral hemorrhage
Severe
Moderate
- Angina
- Chronic kidney disease stage 3B (moderate) GFR 30-44
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Kidney disease with likely reduction in GFR
CARDENE I.V. (NICARDIPINE HCL)
- Hypertension
- Tachycardia
- Headache disorder
- Hypotension
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- None
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal ECG
- Acute myocardial infarction
- Angina
- Atrioventricular block
- Deep venous thrombosis
- Hypophosphatemia
- Hypoxia
- Peripheral edema
- Severe hypotension
- Sinus node dysfunction
- Thrombocytopenic disorder
Less Severe
- Acute confusion
- Conjunctivitis
- Dyspepsia
- Fever
- Hypertonia
- Increased urinary frequency
- Injection site sequelae
- Neck pain
- Thrombophlebitis
- Tinnitus
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Nicardipine
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Nicardipine
Limited data suggest minimal amount excreted w/no resulting infant adv effect
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest minimal amount excreted w/no resulting infant adv effect |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Nicardipine
Renal-Elderly with moderate renal dysfunction may have elevated serum concentrations of nicardipine. Follow blood pressure closely. Hepatic-Elderly with hepatic dysfunction or decreased hepatic blood flow may have elevated serum concentrations of nicardipine. Follow blood pressure closely. Gastrointestinal-May cause constipation or exacerbation of pre-existing constipation. Cardiovascular-May cause peripheral edema in the elderly.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool