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Drug overview for IBANDRONATE SODIUM (ibandronate sodium):
Generic name: IBANDRONATE SODIUM (eye-BAN-droe-nate)
Drug class: Osteoporosis Agents
Therapeutic class: Endocrine
Ibandronate sodium, a synthetic bisphosphonate analog of pyrophosphate, is a bone resorption inhibitor.
No enhanced Uses information available for this drug.
Generic name: IBANDRONATE SODIUM (eye-BAN-droe-nate)
Drug class: Osteoporosis Agents
Therapeutic class: Endocrine
Ibandronate sodium, a synthetic bisphosphonate analog of pyrophosphate, is a bone resorption inhibitor.
No enhanced Uses information available for this drug.
DRUG IMAGES
IBANDRONATE SODIUM 150 MG TAB
The following indications for IBANDRONATE SODIUM (ibandronate sodium) have been approved by the FDA:
Indications:
Post-menopausal osteoporosis prevention
Postmenopausal osteoporosis
Professional Synonyms:
Post-menopausal osteoporosis
Postmenopausal osteoporosis prophylaxis
Indications:
Post-menopausal osteoporosis prevention
Postmenopausal osteoporosis
Professional Synonyms:
Post-menopausal osteoporosis
Postmenopausal osteoporosis prophylaxis
The following dosing information is available for IBANDRONATE SODIUM (ibandronate sodium):
Dosage of ibandronate sodium, which is commercially available as the monosodium monohydrate, is expressed in terms of ibandronate.
The optimal duration of bisphosphonate therapy for osteoporosis has not been established. Safety and efficacy of ibandronate for the management of osteoporosis are based on clinical data over 3 years (for the oral formulation) or 1 year (for the IV formulation). Some evidence suggests that increased durations of bisphosphonate use may be associated with a higher risk of some adverse effects (e.g., jaw osteonecrosis, atypical fractures).
(See Cautions.) All patients receiving a bisphosphonate should have periodic evaluations to determine the need for continued therapy with the drug. Discontinuance of bisphosphonate therapy may be considered after 3-5 years of use for patients who are assessed to be at low risk of fracture. Risk of fracture should be evaluated periodically in patients who discontinue therapy.
The optimal duration of bisphosphonate therapy for osteoporosis has not been established. Safety and efficacy of ibandronate for the management of osteoporosis are based on clinical data over 3 years (for the oral formulation) or 1 year (for the IV formulation). Some evidence suggests that increased durations of bisphosphonate use may be associated with a higher risk of some adverse effects (e.g., jaw osteonecrosis, atypical fractures).
(See Cautions.) All patients receiving a bisphosphonate should have periodic evaluations to determine the need for continued therapy with the drug. Discontinuance of bisphosphonate therapy may be considered after 3-5 years of use for patients who are assessed to be at low risk of fracture. Risk of fracture should be evaluated periodically in patients who discontinue therapy.
Ibandronate sodium is administered orally or by IV injection.
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| IBANDRONATE SODIUM 150 MG TAB | Maintenance | Adults take 1 tablet (150 mg) by oral route once a month (same date) with a full glass of water and remain in upright position at least 1 hour. |
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| IBANDRONATE SODIUM 150 MG TAB | Maintenance | Adults take 1 tablet (150 mg) by oral route once a month (same date) with a full glass of water and remain in upright position at least 1 hour. |
The following drug interaction information is available for IBANDRONATE SODIUM (ibandronate sodium):
There are 0 contraindications.
There are 0 severe interactions.
There are 1 moderate interactions.
The clinician should assess the patient’s characteristics and take action as needed. Actions required for moderate interactions include, but are not limited to, discontinuing one or both agents, adjusting dosage, altering administration.
| Drug Interaction | Drug Names |
|---|---|
| Oral Bisphosphonates/Oral Multivalent Cations SEVERITY LEVEL: 3-Moderate Interaction: Assess the risk to the patient and take action as needed. MECHANISM OF ACTION: Multivalent cations may bind to and inhibit the absorption of oral bisphosphonates.(1-6) CLINICAL EFFECTS: Simultaneous administration of products containing multivalent cations may result in decreased levels of and clinical effects from oral bisphosphonates.(1-6) PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: Instruct patients to separate the administration times of products containing multivalent cations and oral bisphosphonates. Manufacturer recommendations regarding the separation of administration times of oral bisphosphonates and multivalent cations vary. Do NOT give multivalent cation-containing products: - until at least 30 minutes after taking alendronate(1) - within 2 hours of etidronate(2) - until at least 1 hour after taking ibandronate(3) - until at least 30 minutes after taking risedronate(4) - within 2 hours of tiludronate(5) DISCUSSION: Multivalent cations may bind to and inhibit the absorption of oral bisphosphonates, resulting in decreased levels of and clinical effects from these agents.(1-6) Administration of aluminum- or magnesium-containing antacids 1 hour before tiludronate decreased the bioavailability of tiludronate by 60%.(5) |
ACCRUFER, ALUMINUM HYDROXIDE, AUROVELA 24 FE, AUROVELA FE, AURYXIA, BALCOLTRA, BLISOVI 24 FE, BLISOVI FE, CHARLOTTE 24 FE, CLENPIQ, FEIRZA, FERRIC CITRATE, FINZALA, GALZIN, GEMMILY, HAILEY 24 FE, HAILEY FE, JOYEAUX, JUNEL FE, JUNEL FE 24, KAITLIB FE, KAOLIN, LARIN 24 FE, LARIN FE, LAYOLIS FE, LEVONORG-ETH ESTRAD-FE BISGLYC, LO LOESTRIN FE, LOESTRIN FE, MAGNESIUM CHLORIDE, MAGNESIUM CITRATE, MAGNESIUM OXIDE, MAGNESIUM SULFATE, MERZEE, MIBELAS 24 FE, MICROGESTIN FE, MINZOYA, NORETHIN-ETH ESTRA-FERROUS FUM, NORETHINDRONE-E.ESTRADIOL-IRON, SOD SULF-POTASS SULF-MAG SULF, SUFLAVE, SUPREP, SUTAB, TARINA 24 FE, TARINA FE, TARINA FE 1-20 EQ, TAYTULLA, TILIA FE, TRI-LEGEST FE, VELPHORO, WILZIN, WYMZYA FE, XARAH FE, XELRIA FE, ZINC ACETATE, ZINC CHLORIDE, ZINC OXIDE, ZINC SULFATE, ZINC UNDECYLENATE |
The following contraindication information is available for IBANDRONATE SODIUM (ibandronate sodium):
Drug contraindication overview.
Hypocalcemia or known hypersensitivity to ibandronate or any ingredient in the formulation. With oral ibandronate, abnormalities of the esophagus that delay esophageal emptying, such as stricture or achalasia. With oral ibandronate, inability to stand or sit upright for at least 60 minutes.
Hypocalcemia or known hypersensitivity to ibandronate or any ingredient in the formulation. With oral ibandronate, abnormalities of the esophagus that delay esophageal emptying, such as stricture or achalasia. With oral ibandronate, inability to stand or sit upright for at least 60 minutes.
There are 4 contraindications.
Absolute contraindication.
| Contraindication List |
|---|
| Achalasia of esophagus |
| Aseptic necrosis of jaw bone |
| Hypocalcemia |
| Stricture of esophagus |
There are 16 severe contraindications.
Adequate patient monitoring is recommended for safer drug use.
| Severe List |
|---|
| Atypical femoral fracture |
| Barrett's esophagus |
| Bed-ridden |
| Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min |
| Chronic kidney disease stage 5 (failure) GFr<15 ml/min |
| Duodenitis |
| Dysphagia |
| Esophageal dysmotility |
| Esophageal obstruction |
| Esophageal ulcer |
| Esophagitis |
| Gastritis |
| Invasive dental procedure |
| Peptic ulcer |
| Periodontitis |
| Vitamin D deficiency |
There are 6 moderate contraindications.
Clinically significant contraindication, where the condition can be managed or treated before the drug may be given safely.
| Moderate List |
|---|
| Arthralgia |
| Bone pain |
| Heartburn |
| Kidney disease with likely reduction in glomerular filtration rate (GFr) |
| Myalgia |
| Tooth disorder |
The following adverse reaction information is available for IBANDRONATE SODIUM (ibandronate sodium):
Adverse reaction overview.
Adverse effects occurring in at least 2% of patients receiving daily oral ibandronate therapy in osteoporosis treatment or prevention studies and in more patients than with placebo include upper respiratory tract infection, back pain, dyspepsia, bronchitis, pain in the extremities, diarrhea, headache, pneumonia, myalgia, urinary tract infection, hypercholesterolemia, infection (unspecified), dizziness, joint disorder, asthenia, tooth disorder, arthritis, vertigo, vomiting, allergic reaction, pharyngitis, gastritis, and nerve root lesion. Adverse effects occurring in at least 2% of patients receiving once-monthly oral ibandronate include upper abdominal or abdominal pain, hypertension, dyspepsia, arthralgia, nausea, diarrhea, back pain, constipation, influenza, pain in the extremities, nasopharyngitis, headache, influenza-like illness and acute phase inflammatory reaction, localized osteoarthritis, bronchitis, urinary tract infection, dizziness, rash (including pruritic, macular, papular, erythematous, or generalized rash; dermatitis or allergic dermatitis; exanthem; erythema; and dermatitis medicamentosa), myalgia, upper respiratory tract infection, and insomnia. Adverse effects occurring in at least 2% of patients receiving quarterly IV ibandronate therapy for the treatment of osteoporosis include arthralgia, back pain, cystitis, gastroenteritis, upper abdominal or abdominal pain, influenza-like illness and acute phase inflammatory reaction, headache, dyspepsia, nasopharyngitis, constipation, fatigue, diarrhea, pain in the extremities, myalgia, urinary tract infection, osteoarthritis, rash (including pruritic, macular, papular, erythematous, or generalized rash, dermatitis or allergic dermatitis, exanthem, erythema, and dermatitis medicamentosa), bronchitis, and nausea.
Adverse effects occurring in at least 2% of patients receiving daily oral ibandronate therapy in osteoporosis treatment or prevention studies and in more patients than with placebo include upper respiratory tract infection, back pain, dyspepsia, bronchitis, pain in the extremities, diarrhea, headache, pneumonia, myalgia, urinary tract infection, hypercholesterolemia, infection (unspecified), dizziness, joint disorder, asthenia, tooth disorder, arthritis, vertigo, vomiting, allergic reaction, pharyngitis, gastritis, and nerve root lesion. Adverse effects occurring in at least 2% of patients receiving once-monthly oral ibandronate include upper abdominal or abdominal pain, hypertension, dyspepsia, arthralgia, nausea, diarrhea, back pain, constipation, influenza, pain in the extremities, nasopharyngitis, headache, influenza-like illness and acute phase inflammatory reaction, localized osteoarthritis, bronchitis, urinary tract infection, dizziness, rash (including pruritic, macular, papular, erythematous, or generalized rash; dermatitis or allergic dermatitis; exanthem; erythema; and dermatitis medicamentosa), myalgia, upper respiratory tract infection, and insomnia. Adverse effects occurring in at least 2% of patients receiving quarterly IV ibandronate therapy for the treatment of osteoporosis include arthralgia, back pain, cystitis, gastroenteritis, upper abdominal or abdominal pain, influenza-like illness and acute phase inflammatory reaction, headache, dyspepsia, nasopharyngitis, constipation, fatigue, diarrhea, pain in the extremities, myalgia, urinary tract infection, osteoarthritis, rash (including pruritic, macular, papular, erythematous, or generalized rash, dermatitis or allergic dermatitis, exanthem, erythema, and dermatitis medicamentosa), bronchitis, and nausea.
There are 20 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. |
Pneumonia Urinary tract infection |
| Rare/Very Rare |
|---|
|
Anaphylaxis Angioedema Aseptic necrosis of bone in orofacial region Aseptic necrosis of jaw bone Asthma exacerbation Atypical femoral fracture Atypical stress fracture Bone pain Bullous dermatitis Erythema multiforme Esophageal perforation Esophageal ulcer Esophagitis Hypocalcemia Ocular inflammation Stevens-johnson syndrome Stricture of esophagus Uveitis |
There are 27 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
|
Abdominal pain with cramps Back pain Diarrhea Dyspepsia Flu-like symptoms Headache disorder Myalgia Pain in extremities Upper respiratory infection |
Arthralgia Arthritis Bronchitis Constipation Dizziness Gastritis General weakness Hypertension Infection Nausea Pharyngitis Skin rash Tooth disorder Vertigo Vomiting |
| Rare/Very Rare |
|---|
|
Cramps Insomnia Iritis |
The following precautions are available for IBANDRONATE SODIUM (ibandronate sodium):
Safety and efficacy have not been established in children. Ibandronate is not indicated for use in children.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
There are no data in pregnant women to inform any drug-associated risks with ibandronate. The drug is not indicated for use in women of childbearing potential. In reproductive animal studies, maternal and fetal toxicity (including postimplantation loss, developmental anomalies, and deaths) have been observed.
Ibandronate is distributed into milk in rats at concentrations averaging 1.5 times that in plasma; it is not known whether the drug is distributed into milk in humans. It is not known whether ibandronate has any effects on the nursing infant or on milk production.
No overall differences in safety and efficacy relative to younger adults have been observed. However, the possibility that some older patients may exhibit increased sensitivity to the drug cannot be ruled out. The greater frequency of decreased renal function observed in the elderly also should be considered.
The following prioritized warning is available for IBANDRONATE SODIUM (ibandronate sodium):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for IBANDRONATE SODIUM (ibandronate sodium)'s list of indications:
| Post-menopausal osteoporosis prevention | |
| Z78.0 | Asymptomatic menopausal state |
| Postmenopausal osteoporosis | |
| M80.0 | Age-related osteoporosis with current pathological fracture |
| M80.00 | Age-related osteoporosis with current pathological fracture, unspecified site |
| M80.00xA | Age-related osteoporosis with current pathological fracture, unspecified site, initial encounter for fracture |
| M80.00xD | Age-related osteoporosis with current pathological fracture, unspecified site, subsequent encounter for fracture with routine healing |
| M80.00xG | Age-related osteoporosis with current pathological fracture, unspecified site, subsequent encounter for fracture with delayed healing |
| M80.00xK | Age-related osteoporosis with current pathological fracture, unspecified site, subsequent encounter for fracture with nonunion |
| M80.00xP | Age-related osteoporosis with current pathological fracture, unspecified site, subsequent encounter for fracture with malunion |
| M80.00xS | Age-related osteoporosis with current pathological fracture, unspecified site, sequela |
| M80.01 | Age-related osteoporosis with current pathological fracture, shoulder |
| M80.011 | Age-related osteoporosis with current pathological fracture, right shoulder |
| M80.011A | Age-related osteoporosis with current pathological fracture, right shoulder, initial encounter for fracture |
| M80.011D | Age-related osteoporosis with current pathological fracture, right shoulder, subsequent encounter for fracture with routine healing |
| M80.011G | Age-related osteoporosis with current pathological fracture, right shoulder, subsequent encounter for fracture with delayed healing |
| M80.011K | Age-related osteoporosis with current pathological fracture, right shoulder, subsequent encounter for fracture with nonunion |
| M80.011P | Age-related osteoporosis with current pathological fracture, right shoulder, subsequent encounter for fracture with malunion |
| M80.011S | Age-related osteoporosis with current pathological fracture, right shoulder, sequela |
| M80.012 | Age-related osteoporosis with current pathological fracture, left shoulder |
| M80.012A | Age-related osteoporosis with current pathological fracture, left shoulder, initial encounter for fracture |
| M80.012D | Age-related osteoporosis with current pathological fracture, left shoulder, subsequent encounter for fracture with routine healing |
| M80.012G | Age-related osteoporosis with current pathological fracture, left shoulder, subsequent encounter for fracture with delayed healing |
| M80.012K | Age-related osteoporosis with current pathological fracture, left shoulder, subsequent encounter for fracture with nonunion |
| M80.012P | Age-related osteoporosis with current pathological fracture, left shoulder, subsequent encounter for fracture with malunion |
| M80.012S | Age-related osteoporosis with current pathological fracture, left shoulder, sequela |
| M80.019 | Age-related osteoporosis with current pathological fracture, unspecified shoulder |
| M80.019A | Age-related osteoporosis with current pathological fracture, unspecified shoulder, initial encounter for fracture |
| M80.019D | Age-related osteoporosis with current pathological fracture, unspecified shoulder, subsequent encounter for fracture with routine healing |
| M80.019G | Age-related osteoporosis with current pathological fracture, unspecified shoulder, subsequent encounter for fracture with delayed healing |
| M80.019K | Age-related osteoporosis with current pathological fracture, unspecified shoulder, subsequent encounter for fracture with nonunion |
| M80.019P | Age-related osteoporosis with current pathological fracture, unspecified shoulder, subsequent encounter for fracture with malunion |
| M80.019S | Age-related osteoporosis with current pathological fracture, unspecified shoulder, sequela |
| M80.02 | Age-related osteoporosis with current pathological fracture, humerus |
| M80.021 | Age-related osteoporosis with current pathological fracture, right humerus |
| M80.021A | Age-related osteoporosis with current pathological fracture, right humerus, initial encounter for fracture |
| M80.021D | Age-related osteoporosis with current pathological fracture, right humerus, subsequent encounter for fracture with routine healing |
| M80.021G | Age-related osteoporosis with current pathological fracture, right humerus, subsequent encounter for fracture with delayed healing |
| M80.021K | Age-related osteoporosis with current pathological fracture, right humerus, subsequent encounter for fracture with nonunion |
| M80.021P | Age-related osteoporosis with current pathological fracture, right humerus, subsequent encounter for fracture with malunion |
| M80.021S | Age-related osteoporosis with current pathological fracture, right humerus, sequela |
| M80.022 | Age-related osteoporosis with current pathological fracture, left humerus |
| M80.022A | Age-related osteoporosis with current pathological fracture, left humerus, initial encounter for fracture |
| M80.022D | Age-related osteoporosis with current pathological fracture, left humerus, subsequent encounter for fracture with routine healing |
| M80.022G | Age-related osteoporosis with current pathological fracture, left humerus, subsequent encounter for fracture with delayed healing |
| M80.022K | Age-related osteoporosis with current pathological fracture, left humerus, subsequent encounter for fracture with nonunion |
| M80.022P | Age-related osteoporosis with current pathological fracture, left humerus, subsequent encounter for fracture with malunion |
| M80.022S | Age-related osteoporosis with current pathological fracture, left humerus, sequela |
| M80.029 | Age-related osteoporosis with current pathological fracture, unspecified humerus |
| M80.029A | Age-related osteoporosis with current pathological fracture, unspecified humerus, initial encounter for fracture |
| M80.029D | Age-related osteoporosis with current pathological fracture, unspecified humerus, subsequent encounter for fracture with routine healing |
| M80.029G | Age-related osteoporosis with current pathological fracture, unspecified humerus, subsequent encounter for fracture with delayed healing |
| M80.029K | Age-related osteoporosis with current pathological fracture, unspecified humerus, subsequent encounter for fracture with nonunion |
| M80.029P | Age-related osteoporosis with current pathological fracture, unspecified humerus, subsequent encounter for fracture with malunion |
| M80.029S | Age-related osteoporosis with current pathological fracture, unspecified humerus, sequela |
| M80.03 | Age-related osteoporosis with current pathological fracture, forearm |
| M80.031 | Age-related osteoporosis with current pathological fracture, right forearm |
| M80.031A | Age-related osteoporosis with current pathological fracture, right forearm, initial encounter for fracture |
| M80.031D | Age-related osteoporosis with current pathological fracture, right forearm, subsequent encounter for fracture with routine healing |
| M80.031G | Age-related osteoporosis with current pathological fracture, right forearm, subsequent encounter for fracture with delayed healing |
| M80.031K | Age-related osteoporosis with current pathological fracture, right forearm, subsequent encounter for fracture with nonunion |
| M80.031P | Age-related osteoporosis with current pathological fracture, right forearm, subsequent encounter for fracture with malunion |
| M80.031S | Age-related osteoporosis with current pathological fracture, right forearm, sequela |
| M80.032 | Age-related osteoporosis with current pathological fracture, left forearm |
| M80.032A | Age-related osteoporosis with current pathological fracture, left forearm, initial encounter for fracture |
| M80.032D | Age-related osteoporosis with current pathological fracture, left forearm, subsequent encounter for fracture with routine healing |
| M80.032G | Age-related osteoporosis with current pathological fracture, left forearm, subsequent encounter for fracture with delayed healing |
| M80.032K | Age-related osteoporosis with current pathological fracture, left forearm, subsequent encounter for fracture with nonunion |
| M80.032P | Age-related osteoporosis with current pathological fracture, left forearm, subsequent encounter for fracture with malunion |
| M80.032S | Age-related osteoporosis with current pathological fracture, left forearm, sequela |
| M80.039 | Age-related osteoporosis with current pathological fracture, unspecified forearm |
| M80.039A | Age-related osteoporosis with current pathological fracture, unspecified forearm, initial encounter for fracture |
| M80.039D | Age-related osteoporosis with current pathological fracture, unspecified forearm, subsequent encounter for fracture with routine healing |
| M80.039G | Age-related osteoporosis with current pathological fracture, unspecified forearm, subsequent encounter for fracture with delayed healing |
| M80.039K | Age-related osteoporosis with current pathological fracture, unspecified forearm, subsequent encounter for fracture with nonunion |
| M80.039P | Age-related osteoporosis with current pathological fracture, unspecified forearm, subsequent encounter for fracture with malunion |
| M80.039S | Age-related osteoporosis with current pathological fracture, unspecified forearm, sequela |
| M80.04 | Age-related osteoporosis with current pathological fracture, hand |
| M80.041 | Age-related osteoporosis with current pathological fracture, right hand |
| M80.041A | Age-related osteoporosis with current pathological fracture, right hand, initial encounter for fracture |
| M80.041D | Age-related osteoporosis with current pathological fracture, right hand, subsequent encounter for fracture with routine healing |
| M80.041G | Age-related osteoporosis with current pathological fracture, right hand, subsequent encounter for fracture with delayed healing |
| M80.041K | Age-related osteoporosis with current pathological fracture, right hand, subsequent encounter for fracture with nonunion |
| M80.041P | Age-related osteoporosis with current pathological fracture, right hand, subsequent encounter for fracture with malunion |
| M80.041S | Age-related osteoporosis with current pathological fracture, right hand, sequela |
| M80.042 | Age-related osteoporosis with current pathological fracture, left hand |
| M80.042A | Age-related osteoporosis with current pathological fracture, left hand, initial encounter for fracture |
| M80.042D | Age-related osteoporosis with current pathological fracture, left hand, subsequent encounter for fracture with routine healing |
| M80.042G | Age-related osteoporosis with current pathological fracture, left hand, subsequent encounter for fracture with delayed healing |
| M80.042K | Age-related osteoporosis with current pathological fracture, left hand, subsequent encounter for fracture with nonunion |
| M80.042P | Age-related osteoporosis with current pathological fracture, left hand, subsequent encounter for fracture with malunion |
| M80.042S | Age-related osteoporosis with current pathological fracture, left hand, sequela |
| M80.049 | Age-related osteoporosis with current pathological fracture, unspecified hand |
| M80.049A | Age-related osteoporosis with current pathological fracture, unspecified hand, initial encounter for fracture |
| M80.049D | Age-related osteoporosis with current pathological fracture, unspecified hand, subsequent encounter for fracture with routine healing |
| M80.049G | Age-related osteoporosis with current pathological fracture, unspecified hand, subsequent encounter for fracture with delayed healing |
| M80.049K | Age-related osteoporosis with current pathological fracture, unspecified hand, subsequent encounter for fracture with nonunion |
| M80.049P | Age-related osteoporosis with current pathological fracture, unspecified hand, subsequent encounter for fracture with malunion |
| M80.049S | Age-related osteoporosis with current pathological fracture, unspecified hand, sequela |
| M80.05 | Age-related osteoporosis with current pathological fracture, femur |
| M80.051 | Age-related osteoporosis with current pathological fracture, right femur |
| M80.051A | Age-related osteoporosis with current pathological fracture, right femur, initial encounter for fracture |
| M80.051D | Age-related osteoporosis with current pathological fracture, right femur, subsequent encounter for fracture with routine healing |
| M80.051G | Age-related osteoporosis with current pathological fracture, right femur, subsequent encounter for fracture with delayed healing |
| M80.051K | Age-related osteoporosis with current pathological fracture, right femur, subsequent encounter for fracture with nonunion |
| M80.051P | Age-related osteoporosis with current pathological fracture, right femur, subsequent encounter for fracture with malunion |
| M80.051S | Age-related osteoporosis with current pathological fracture, right femur, sequela |
| M80.052 | Age-related osteoporosis with current pathological fracture, left femur |
| M80.052A | Age-related osteoporosis with current pathological fracture, left femur, initial encounter for fracture |
| M80.052D | Age-related osteoporosis with current pathological fracture, left femur, subsequent encounter for fracture with routine healing |
| M80.052G | Age-related osteoporosis with current pathological fracture, left femur, subsequent encounter for fracture with delayed healing |
| M80.052K | Age-related osteoporosis with current pathological fracture, left femur, subsequent encounter for fracture with nonunion |
| M80.052P | Age-related osteoporosis with current pathological fracture, left femur, subsequent encounter for fracture with malunion |
| M80.052S | Age-related osteoporosis with current pathological fracture, left femur, sequela |
| M80.059 | Age-related osteoporosis with current pathological fracture, unspecified femur |
| M80.059A | Age-related osteoporosis with current pathological fracture, unspecified femur, initial encounter for fracture |
| M80.059D | Age-related osteoporosis with current pathological fracture, unspecified femur, subsequent encounter for fracture with routine healing |
| M80.059G | Age-related osteoporosis with current pathological fracture, unspecified femur, subsequent encounter for fracture with delayed healing |
| M80.059K | Age-related osteoporosis with current pathological fracture, unspecified femur, subsequent encounter for fracture with nonunion |
| M80.059P | Age-related osteoporosis with current pathological fracture, unspecified femur, subsequent encounter for fracture with malunion |
| M80.059S | Age-related osteoporosis with current pathological fracture, unspecified femur, sequela |
| M80.06 | Age-related osteoporosis with current pathological fracture, lower leg |
| M80.061 | Age-related osteoporosis with current pathological fracture, right lower leg |
| M80.061A | Age-related osteoporosis with current pathological fracture, right lower leg, initial encounter for fracture |
| M80.061D | Age-related osteoporosis with current pathological fracture, right lower leg, subsequent encounter for fracture with routine healing |
| M80.061G | Age-related osteoporosis with current pathological fracture, right lower leg, subsequent encounter for fracture with delayed healing |
| M80.061K | Age-related osteoporosis with current pathological fracture, right lower leg, subsequent encounter for fracture with nonunion |
| M80.061P | Age-related osteoporosis with current pathological fracture, right lower leg, subsequent encounter for fracture with malunion |
| M80.061S | Age-related osteoporosis with current pathological fracture, right lower leg, sequela |
| M80.062 | Age-related osteoporosis with current pathological fracture, left lower leg |
| M80.062A | Age-related osteoporosis with current pathological fracture, left lower leg, initial encounter for fracture |
| M80.062D | Age-related osteoporosis with current pathological fracture, left lower leg, subsequent encounter for fracture with routine healing |
| M80.062G | Age-related osteoporosis with current pathological fracture, left lower leg, subsequent encounter for fracture with delayed healing |
| M80.062K | Age-related osteoporosis with current pathological fracture, left lower leg, subsequent encounter for fracture with nonunion |
| M80.062P | Age-related osteoporosis with current pathological fracture, left lower leg, subsequent encounter for fracture with malunion |
| M80.062S | Age-related osteoporosis with current pathological fracture, left lower leg, sequela |
| M80.069 | Age-related osteoporosis with current pathological fracture, unspecified lower leg |
| M80.069A | Age-related osteoporosis with current pathological fracture, unspecified lower leg, initial encounter for fracture |
| M80.069D | Age-related osteoporosis with current pathological fracture, unspecified lower leg, subsequent encounter for fracture with routine healing |
| M80.069G | Age-related osteoporosis with current pathological fracture, unspecified lower leg, subsequent encounter for fracture with delayed healing |
| M80.069K | Age-related osteoporosis with current pathological fracture, unspecified lower leg, subsequent encounter for fracture with nonunion |
| M80.069P | Age-related osteoporosis with current pathological fracture, unspecified lower leg, subsequent encounter for fracture with malunion |
| M80.069S | Age-related osteoporosis with current pathological fracture, unspecified lower leg, sequela |
| M80.07 | Age-related osteoporosis with current pathological fracture, ankle and foot |
| M80.071 | Age-related osteoporosis with current pathological fracture, right ankle and foot |
| M80.071A | Age-related osteoporosis with current pathological fracture, right ankle and foot, initial encounter for fracture |
| M80.071D | Age-related osteoporosis with current pathological fracture, right ankle and foot, subsequent encounter for fracture with routine healing |
| M80.071G | Age-related osteoporosis with current pathological fracture, right ankle and foot, subsequent encounter for fracture with delayed healing |
| M80.071K | Age-related osteoporosis with current pathological fracture, right ankle and foot, subsequent encounter for fracture with nonunion |
| M80.071P | Age-related osteoporosis with current pathological fracture, right ankle and foot, subsequent encounter for fracture with malunion |
| M80.071S | Age-related osteoporosis with current pathological fracture, right ankle and foot, sequela |
| M80.072 | Age-related osteoporosis with current pathological fracture, left ankle and foot |
| M80.072A | Age-related osteoporosis with current pathological fracture, left ankle and foot, initial encounter for fracture |
| M80.072D | Age-related osteoporosis with current pathological fracture, left ankle and foot, subsequent encounter for fracture with routine healing |
| M80.072G | Age-related osteoporosis with current pathological fracture, left ankle and foot, subsequent encounter for fracture with delayed healing |
| M80.072K | Age-related osteoporosis with current pathological fracture, left ankle and foot, subsequent encounter for fracture with nonunion |
| M80.072P | Age-related osteoporosis with current pathological fracture, left ankle and foot, subsequent encounter for fracture with malunion |
| M80.072S | Age-related osteoporosis with current pathological fracture, left ankle and foot, sequela |
| M80.079 | Age-related osteoporosis with current pathological fracture, unspecified ankle and foot |
| M80.079A | Age-related osteoporosis with current pathological fracture, unspecified ankle and foot, initial encounter for fracture |
| M80.079D | Age-related osteoporosis with current pathological fracture, unspecified ankle and foot, subsequent encounter for fracture with routine healing |
| M80.079G | Age-related osteoporosis with current pathological fracture, unspecified ankle and foot, subsequent encounter for fracture with delayed healing |
| M80.079K | Age-related osteoporosis with current pathological fracture, unspecified ankle and foot, subsequent encounter for fracture with nonunion |
| M80.079P | Age-related osteoporosis with current pathological fracture, unspecified ankle and foot, subsequent encounter for fracture with malunion |
| M80.079S | Age-related osteoporosis with current pathological fracture, unspecified ankle and foot, sequela |
| M80.08 | Age-related osteoporosis with current pathological fracture, vertebra(e) |
| M80.08xA | Age-related osteoporosis with current pathological fracture, vertebra(e), initial encounter for fracture |
| M80.08xD | Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with routine healing |
| M80.08xG | Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with delayed healing |
| M80.08xK | Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with nonunion |
| M80.08xP | Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with malunion |
| M80.08xS | Age-related osteoporosis with current pathological fracture, vertebra(e), sequela |
| M80.0A | Age-related osteoporosis with current pathological fracture, other site |
| M80.0AxA | Age-related osteoporosis with current pathological fracture, other site, initial encounter for fracture |
| M80.0AxD | Age-related osteoporosis with current pathological fracture, other site, subsequent encounter for fracture with routine healing |
| M80.0AxG | Age-related osteoporosis with current pathological fracture, other site, subsequent encounter for fracture with delayed healing |
| M80.0AxK | Age-related osteoporosis with current pathological fracture, other site, subsequent encounter for fracture with nonunion |
| M80.0AxP | Age-related osteoporosis with current pathological fracture, other site, subsequent encounter for fracture with malunion |
| M80.0AxS | Age-related osteoporosis with current pathological fracture, other site, sequela |
| M80.0B | Age-related osteoporosis with current pathological fracture, pelvis |
| M80.0B1 | Age-related osteoporosis with current pathological fracture, right pelvis |
| M80.0B1A | Age-related osteoporosis with current pathological fracture, right pelvis, initial encounter for fracture |
| M80.0B1D | Age-related osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with routine healing |
| M80.0B1G | Age-related osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with delayed healing |
| M80.0B1K | Age-related osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with nonunion |
| M80.0B1P | Age-related osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with malunion |
| M80.0B1S | Age-related osteoporosis with current pathological fracture, right pelvis, sequela |
| M80.0B2 | Age-related osteoporosis with current pathological fracture, left pelvis |
| M80.0B2A | Age-related osteoporosis with current pathological fracture, left pelvis, initial encounter for fracture |
| M80.0B2D | Age-related osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with routine healing |
| M80.0B2G | Age-related osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with delayed healing |
| M80.0B2K | Age-related osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with nonunion |
| M80.0B2P | Age-related osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with malunion |
| M80.0B2S | Age-related osteoporosis with current pathological fracture, left pelvis, sequela |
| M80.0B9 | Age-related osteoporosis with current pathological fracture, unspecified pelvis |
| M80.0B9A | Age-related osteoporosis with current pathological fracture, unspecified pelvis, initial encounter for fracture |
| M80.0B9D | Age-related osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with routine healing |
| M80.0B9G | Age-related osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with delayed healing |
| M80.0B9K | Age-related osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with nonunion |
| M80.0B9P | Age-related osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with malunion |
| M80.0B9S | Age-related osteoporosis with current pathological fracture, unspecified pelvis, sequela |
| M80.8B | Other osteoporosis with current pathological fracture, pelvis |
| M80.8B1 | Other osteoporosis with current pathological fracture, right pelvis |
| M80.8B1A | Other osteoporosis with current pathological fracture, right pelvis, initial encounter for fracture |
| M80.8B1D | Other osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with routine healing |
| M80.8B1G | Other osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with delayed healing |
| M80.8B1K | Other osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with nonunion |
| M80.8B1P | Other osteoporosis with current pathological fracture, right pelvis, subsequent encounter for fracture with malunion |
| M80.8B1S | Other osteoporosis with current pathological fracture, right pelvis, sequela |
| M80.8B2 | Other osteoporosis with current pathological fracture, left pelvis |
| M80.8B2A | Other osteoporosis with current pathological fracture, left pelvis, initial encounter for fracture |
| M80.8B2D | Other osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with routine healing |
| M80.8B2G | Other osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with delayed healing |
| M80.8B2K | Other osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with nonunion |
| M80.8B2P | Other osteoporosis with current pathological fracture, left pelvis, subsequent encounter for fracture with malunion |
| M80.8B2S | Other osteoporosis with current pathological fracture, left pelvis, sequela |
| M80.8B9 | Other osteoporosis with current pathological fracture, unspecified pelvis |
| M80.8B9A | Other osteoporosis with current pathological fracture, unspecified pelvis, initial encounter for fracture |
| M80.8B9D | Other osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with routine healing |
| M80.8B9G | Other osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with delayed healing |
| M80.8B9K | Other osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with nonunion |
| M80.8B9P | Other osteoporosis with current pathological fracture, unspecified pelvis, subsequent encounter for fracture with malunion |
| M80.8B9S | Other osteoporosis with current pathological fracture, unspecified pelvis, sequela |
| M81.0 | Age-related osteoporosis without current pathological fracture |
Formulary Reference Tool