MULTI-SYMPTOM-NT SEVERE COLD (dextromethorphan/phenylephrine/acetaminophen/diphenhydramine)

Contraindicated



• Azilect
• Eldepryl
• isocarboxazid
• linezolid
• Marplan
• Matulane
• methylene blue (antidote)
• Nardil
• Parnate
• phenelzine
• procarbazine
• rasagiline
• selegiline HCl
• tranylcypromine
• Zelapar
• Zyvox

Severe



• bromocriptine
• cabergoline
• Cafergot
• Compound 347
• Cycloset
• D.h.e.45
• dihydroergotamine
• enflurane
• ergoloid
• Ergomar
• ergotamine tartrate
• ergotamine-caffeine
• Forane
• isoflurane
• methylergonovine
• Migergot
• Migranal
• Parlodel
• sevoflurane
• Sojourn
• Soltamox
• tamoxifen
• Terrell
• Ultane

Contraindicated



• Acetaminophen overdose
• Acute hepatic failure
• Acute hepatitis C
• Acute myocardial infarction
• Arterial thrombosis
• Severe uncontrolled hypertension
• Ventricular tachycardia

Severe



• Acute hepatitis
• Acute pancreatitis
• Angle-closure glaucoma
• Benign prostatic hyperplasia
• Bladder outflow obstruction
• Bradycardia
• Chronic idiopathic constipation
• Coronary artery disease
• Disease of liver
• Hypertension
• Hyperthyroidism
• Incomplete AV heart block
• Protein-calorie malnutrition
• Severe arteriosclerotic vascular disease
• Severe renal impairment
• Shock
• Stenosing peptic ulcer
• Systemic mastocytosis
• Urinary retention

Contraindicated

Dextromethorphan (OTC)

Do not use in pediatrics <6 years of age unless clinician consultation.

Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation.

Possible risk of CNS excitation, convulsions in newborns.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 30 Days – 6 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 1 Day – 29 Days
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.

Diphenhydramine (Cough-Cold)

Do not use in pediatrics <6 years of age unless clinician consultation.

Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation.

Possible risk of CNS excitation, convulsions in newborns.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation.
• 30 Days – 6 Years
• 1 Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation.
• 1 Day – 29 Days
• 1 Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation.

Diphenhydramine (Systemic)

Do not use in pediatrics <6 years of age unless clinician consultation.

Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation.

Possible risk of CNS excitation, convulsions in newborns.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Possible risk of CNS excitation, convulsions in newborns.
• 30 Days – 6 Years
• 1 Possible risk of CNS excitation, convulsions in newborns.
• 1 Day – 29 Days
• 1 Possible risk of CNS excitation, convulsions in newborns.

Phenylephrine (Oral,Rectal)

Do not use in pediatrics <6 years of age unless clinician consultation.

Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation.

Possible risk of CNS excitation, convulsions in newborns.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
• 30 Days – 6 Years
• 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
• 1 Day – 29 Days
• 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.

Severe Precaution

None

Management or Monitoring Precaution

Acetaminophen (oral,rectal)

Use weight based dosing in children less than 12 years.

• 1 Day – 12 Years
• Use weight based dosing in children less than 12 years.