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Drug overview for LUBRICATING JELLY (CHLORHEXID) (chlorhexidine gluconate/glycerin/hydroxyethylcellulose):
Generic name: chlorhexidine gluconate/glycerin/hydroxyethylcellulose
Drug class:
Therapeutic class: Dermatological
Chlorhexidine gluconate, a cationic bisbiguanide, is a topical anti-infective agent.
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph. Chlorhexidine gluconate 2 or 4% solution in a sudsing base (chlorhexidine gluconate skin cleanser) is used topically as an anti-infective skin cleanser for surgical hand antisepsis (i.e., hand scrub), preoperative skin preparation, routine hand hygiene in health-care personnel, and skin wound and general skin cleansing. Alcohol-based chlorhexidine gluconate 0.5
or 1% solution with emollients (chlorhexidine gluconate hand rub) is used topically as an anti-infective hand rub for routine hand hygiene in health-care personnel; the 1% solution in an alcohol base with emollients also is used topically for surgical hand antisepsis (i.e., hand rub). In addition, chlorhexidine gluconate is used topically for skin disinfection prior to insertion of catheters+, including intravascular, central venous, and arterial catheters, and topical dressings containing chlorhexidine gluconate 20% are used for postinsertion site care in patients with vascular and nonvascular percutaneous devices. Topical chlorhexidine gluconate appears to have a more rapid bactericidal effect than similar topical preparations containing povidone-iodine, triclosan, or hexachlorophene. In addition, chlorhexidine gluconate has persistent or residual anti-infective activity comparable to that reported with hexachlorophene or triclosan, which prevents regrowth of microorganisms on the skin; however, chlorhexidine gluconate has a broader spectrum of activity than these other topical agents, particularly against gram-negative bacteria.
Generic name: chlorhexidine gluconate/glycerin/hydroxyethylcellulose
Drug class:
Therapeutic class: Dermatological
Chlorhexidine gluconate, a cationic bisbiguanide, is a topical anti-infective agent.
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph. Chlorhexidine gluconate 2 or 4% solution in a sudsing base (chlorhexidine gluconate skin cleanser) is used topically as an anti-infective skin cleanser for surgical hand antisepsis (i.e., hand scrub), preoperative skin preparation, routine hand hygiene in health-care personnel, and skin wound and general skin cleansing. Alcohol-based chlorhexidine gluconate 0.5
or 1% solution with emollients (chlorhexidine gluconate hand rub) is used topically as an anti-infective hand rub for routine hand hygiene in health-care personnel; the 1% solution in an alcohol base with emollients also is used topically for surgical hand antisepsis (i.e., hand rub). In addition, chlorhexidine gluconate is used topically for skin disinfection prior to insertion of catheters+, including intravascular, central venous, and arterial catheters, and topical dressings containing chlorhexidine gluconate 20% are used for postinsertion site care in patients with vascular and nonvascular percutaneous devices. Topical chlorhexidine gluconate appears to have a more rapid bactericidal effect than similar topical preparations containing povidone-iodine, triclosan, or hexachlorophene. In addition, chlorhexidine gluconate has persistent or residual anti-infective activity comparable to that reported with hexachlorophene or triclosan, which prevents regrowth of microorganisms on the skin; however, chlorhexidine gluconate has a broader spectrum of activity than these other topical agents, particularly against gram-negative bacteria.
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The following indications for LUBRICATING JELLY (CHLORHEXID) (chlorhexidine gluconate/glycerin/hydroxyethylcellulose) have been approved by the FDA:
Indications:
None.
Professional Synonyms:
None.
Indications:
None.
Professional Synonyms:
None.