Please wait while the formulary information is being retrieved.
Drug overview for 3-DAY VAGINAL CREAM (clotrimazole):
Generic name: CLOTRIMAZOLE (kloe-TRIM-a-zole)
Drug class: Vaginal Antifungal Agents
Therapeutic class: Vaginal Products
Clotrimazole, an imidazole derivative, is a synthetic azole antifungal agent.
No enhanced Uses information available for this drug.
Generic name: CLOTRIMAZOLE (kloe-TRIM-a-zole)
Drug class: Vaginal Antifungal Agents
Therapeutic class: Vaginal Products
Clotrimazole, an imidazole derivative, is a synthetic azole antifungal agent.
No enhanced Uses information available for this drug.
DRUG IMAGES
No Image Available
The following indications for 3-DAY VAGINAL CREAM (clotrimazole) have been approved by the FDA:
Indications:
Vulvovaginal candidiasis
Professional Synonyms:
Vaginal candidiasis
Vulvovaginal candidosis
Vulvovaginal moniliasis
Indications:
Vulvovaginal candidiasis
Professional Synonyms:
Vaginal candidiasis
Vulvovaginal candidosis
Vulvovaginal moniliasis
The following dosing information is available for 3-DAY VAGINAL CREAM (clotrimazole):
No enhanced Dosing information available for this drug.
Clotrimazole is administered topically to the oropharyngeal area as an oral lozenge, to the skin as a cream or solution, or intravaginally as a vaginal cream. The topical cream and solution are not intended for ophthalmic use. Clotrimazole also is available in fixed combination with betamethasone dipropionate as a cream or lotion; see prescribing information for the combination product for additional details.
Store clotrimazole oral lozenges, topical cream, and topical solution at 20--25degreesC. Avoid freezing oral lozenges.
Store clotrimazole oral lozenges, topical cream, and topical solution at 20--25degreesC. Avoid freezing oral lozenges.
No dosing information available.
No generic dosing information available.
The following drug interaction information is available for 3-DAY VAGINAL CREAM (clotrimazole):
There are 0 contraindications.
There are 0 severe interactions.
There are 0 moderate interactions.
The following contraindication information is available for 3-DAY VAGINAL CREAM (clotrimazole):
Drug contraindication overview.
*Known hypersensitivity to clotrimazole or other imidazoles or any ingredient in the formulation.
*Known hypersensitivity to clotrimazole or other imidazoles or any ingredient in the formulation.
There are 0 contraindications.
There are 0 severe contraindications.
There are 1 moderate contraindications.
Clinically significant contraindication, where the condition can be managed or treated before the drug may be given safely.
| Moderate List |
|---|
| No disease contraindications |
The following adverse reaction information is available for 3-DAY VAGINAL CREAM (clotrimazole):
Adverse reaction overview.
Lozenge: nausea, vomiting, unpleasant mouth sensations, and pruritus. Topical cream or solution: blistering, erythema, edema, pruritus, burning, stinging, peeling, urticaria, and general irritation of skin.
Lozenge: nausea, vomiting, unpleasant mouth sensations, and pruritus. Topical cream or solution: blistering, erythema, edema, pruritus, burning, stinging, peeling, urticaria, and general irritation of skin.
There are 7 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. | None. |
| Rare/Very Rare |
|---|
|
Abnormal vaginal bleeding Anaphylaxis Angioedema Bronchospastic pulmonary disease Dyspnea Toxic epidermal necrolysis Urticaria |
There are 20 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. |
Dysmenorrhea Fever Genital organ pruritus Vaginal discharge |
| Rare/Very Rare |
|---|
|
Acute abdominal pain Chills Contact dermatitis Cystitis Dizziness Facial edema Flu-like symptoms General weakness Headache disorder Nausea Pruritus of skin Skin rash Vaginal burning Vaginal irritation Vaginitis Vulvovaginal pain |
The following precautions are available for 3-DAY VAGINAL CREAM (clotrimazole):
Safety and efficacy of clotrimazole lozenges have not been established in children <3 years of age. Safety and efficacy of prophylactic therapy with clotrimazole lozenges have not been established in children. Clotrimazole topical cream or solution is not recommended for self-medication in children <3 years of age.
Clotrimazole vaginal cream is not recommended for self-medication in children <12 years of age. Preparations containing clotrimazole in fixed combination with betamethasone dipropionate are not recommended for use in children <17 years of age or for diaper dermatitis.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Clotrimazole vaginal cream is not recommended for self-medication in children <12 years of age. Preparations containing clotrimazole in fixed combination with betamethasone dipropionate are not recommended for use in children <17 years of age or for diaper dermatitis.
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
There are no adequate and controlled studies of clotrimazole lozenges in pregnant women; the drug should be used during pregnancy only if the potential benefits justify the potential risks to the fetus. In clinical trials, use of intravaginal clotrimazole in pregnant women in the second and third trimester was not associated with adverse effects; there are no adequate and well-controlled studies in pregnant women in the first trimester. . In animal reproductive studies, clotrimazole demonstrated embryotoxic effects, but was not teratogenic when given in doses significantly higher than the recommended human dose.
It is not known whether clotrimazole is excreted in human milk, caution should be exercised when the drug is used in nursing woman.
There were an insufficient number of patients >=65 years of age in clinical studies of clotrimazole lozenges to determine whether geriatric patients respond differently from younger patients; other reported experience did not find any differences in response between these patients.
The following prioritized warning is available for 3-DAY VAGINAL CREAM (clotrimazole):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for 3-DAY VAGINAL CREAM (clotrimazole)'s list of indications:
| Vulvovaginal candidiasis | |
| B37.3 | Candidiasis of vulva and vagina |
| B37.31 | Acute candidiasis of vulva and vagina |
| B37.32 | Chronic candidiasis of vulva and vagina |
Formulary Reference Tool