Please wait while the formulary information is being retrieved.
KORLYM (MIFEPRISTONE)
- Type 2 diabetes adjunct in cushing's syndrome
300 mg tablet
- 1 tablet (300 mg) by oral route once daily
Type 2 diabetes adjunct in cushing's syndrome
- 4 tablets (1,200 mg) by oral route once daily
- 1 tablet (300 mg) by oral route once daily
- 2 tablets (600 mg) by oral route once daily
- 3 tablets (900 mg) by oral route once daily
- Abstral
- Actiq
- Advicor
- Alfenta
- alfentanil
- Altoprev
- Cafergot
- cyclosporine
- cyclosporine modified
- D.h.e.45
- dextromethorphan-quinidine
- dihydroergotamine
- Duragesic
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- ezetimibe-simvastatin
- fentanyl
- fentanyl citrate
- fentanyl citrate (PF)
- Fentora
- Gengraf
- Latuda
- Lazanda
- lovastatin
- lurasidone
- Mevacor
- midazolam
- Migergot
- Migranal
- Neoral
- niacin-lovastatin
- niacin-simvastatin
- Nuedexta
- Orap
- pimozide
- quinidine gluconate
- quinidine sulfate
- Rapamune
- Revatio
- Sandimmune
- sildenafil
- Simcor
- simvastatin
- sirolimus
- Sublimaze (pf)
- Subsys
- triazolam
- Viagra
- Vytorin 10-10
- Vytorin 10-20
- Vytorin 10-40
- Vytorin 10-80
- Zocor
Contraindicated
- A-hydrocort
- A-methapred
- Abraxane
- Advair Diskus
- Advair Hfa
- Aerospan
- Altavera (28)
- Alvesco
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- amoxicil-clarithromy-lansopraz
- Anucort-hc
- Anusol-hc
- Apri
- Aranelle (28)
- Aristospan Intra-articular
- Aristospan Intralesional
- Asmanex Twisthaler
- Aubra
- Aviane
- azelastine-fluticasone
- Azurette (28)
- Balziva (28)
- beclomethasone diprop (AQ)
- beclomethasone dipropionate
- Beconase Aq
- betamethasone acet & sod phos
- Beyaz
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- boceprevir
- Breo Ellipta
- Brevicon (28)
- Briellyn
- budesonide
- budesonide-formoterol
- Camila
- Camrese
- Camrese Lo
- Caziant (28)
- Celebrex
- celecoxib
- Celestone Soluspan
- Cerebyx
- Chateal
- ciclesonide
- clarithromycin
- Colocort
- conivaptan in 5 % dextrose
- Cortef
- Cortenema
- Cortifoam
- cortisone
- Coumadin
- Crixivan
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- Depo-medrol
- Depo-provera
- Depo-subq Provera 104
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- drospirenone-e.estradiol-lm.FA
- drospirenone-ethinyl estradiol
- Dulera
- Dymista
- Elinest
- elvitegr-cobicist-emtric-tenof
- Emoquette
- Enpresse
- Enskyce
- Entocort Ec
- enzalutamide
- Errin
- Estarylla
- estradiol valerate-dienogest
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- Ez Use Joint-tunnel-trigger
- Falmina (28)
- Femcon Fe
- First-duke's
- First-mary's Mouthwash
- Flo-pred
- Flonase
- Flovent Diskus
- Flovent Hfa
- fludrocortisone
- flunisolide
- fluticasone
- fluticasone furoate
- fluticasone-salmeterol
- fluticasone-vilanterol
- fosphenytoin
- Generess Fe
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- Grx Hicort 25
- Heather
- Hemril-30
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- Incivek
- indinavir
- Introvale
- itraconazole
- Jantoven
- Jencycla
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kaletra
- Kariva (28)
- Kelnor 1/35 (28)
- Kenalog
- Ketek
- ketoconazole
- Kurvelo
- L norgest&E estradiol-E estrad
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- lopinavir-ritonavir
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- Medrol
- Medrol (pak)
- medroxyprogesterone
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Millipred
- Millipred Dp
- Minastrin 24 Fe
- Mircette (28)
- Mirena
- Modicon (28)
- mometasone
- mometasone-formoterol
- Mono-linyah
- Mononessa (28)
- My Way
- Myzilra
- Nasacort
- Nasacort Aq
- Nasonex
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- nefazodone
- nelfinavir
- Nexplanon
- Next Choice One Dose
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Nuvaring
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Ocella
- Ogestrel (28)
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Omnaris
- Onmel
- Onxol
- Orapred
- Orapred Odt
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- paclitaxel
- paclitaxel-protein bound
- Pediapred
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Philith
- Physicians Ez Use M-pred
- Pimtrea (28)
- Pirmella
- Plan B One-step
- Portia
- posaconazole
- Prandimet
- Prandin
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- Previfem
- Prevpac
- Proctocort
- Pulmicort
- Pulmicort Flexhaler
- Qnasl
- Quartette
- Quasense
- Qvar
- Rayos
- Reclipsen (28)
- Rectacort-hc
- repaglinide
- repaglinide-metformin
- Rhinocort Aqua
- ritonavir
- Safyral
- Seasonique
- Skyla
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Sporanox
- Sporanox Pulsepak
- Sprintec (28)
- Sronyx
- Stribild
- Syeda
- Symbicort
- telaprevir
- telithromycin
- Tilia Fe
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- Trinessa (28)
- Trivora (28)
- Uceris
- Vaprisol
- Velivet Triphasic Regimen (28)
- Veramyst
- Veripred 20
- Vestura (28)
- Vfend
- Vfend Iv
- Victrelis
- Viorele (28)
- Viracept
- voriconazole
- Vyfemla (28)
- warfarin
- Wera (28)
- Wymzya Fe
- Xtandi
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zetonna
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- Abilify
- Abilify Discmelt
- Abilify Maintena
- aripiprazole
- Acute intermittent porphyria
- Congenital long QT syndrome
- Endometrial carcinoma
- Erythropoietic protoporphyria
- Hepatic porphyria
- Porphyria cutanea tarda
- Pregnancy
- Variegate porphyria
Contraindicated
- Acute adrenocortical insufficiency
- Endometrial hyperplasia
- Hypokalemia
- Increased risk of bleeding
- Increased risk of bleeding due to coagulation disorder
- Pneumocystis jirovecii pneumonia
Severe
Moderate
- None
KORLYM (MIFEPRISTONE)
- Type 2 diabetes adjunct in cushing's syndrome
- Hypokalemia
- Uterine cramps
- Abnormal vaginal bleeding
- Anorexia
- Arthralgias
- Back pain
- Chills
- Diarrhea
- Dizziness
- Endometrial hyperplasia
- Fatigue
- Fever
- General weakness
- Headache disorder
- Hypertension
- Nausea
- Peripheral edema
- Vomiting
More Frequent
Severe
Less Severe
- Hypertriglyceridemia
- Hypoglycemic disorder
- Viral infection
- Acute abdominal pain
- Dyspepsia
- Edema
- Gastroesophageal reflux disease
- Insomnia
- Malaise
- Non-cardiac chest pain
- Polydipsia
- Vaginitis
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Adrenal cortical insufficiency
- Anaphylaxis
- Anemia
- Angioedema
- Bacterial infection
- Bacterial sepsis
- Hypotension
- Infection
- Inflammatory disease of female pelvic organs
- Orthostatic hypotension
- Prolonged QT interval
- Syncope
- Uterine rupture in pregnancy
Less Severe
- Dyspnea
- Limb pain
- Pruritus of skin
- Sinusitis
- Skin rash
- Symptoms of anxiety
- Tachycardia
- Urticaria
- Vaginal discharge
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Mifepristone
Safety and efficacy not established.
- 1 Day – 18 Years
- Safety and efficacy not established.
Mifepristone (300Mg)
- Severity Level:
X
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Mifepristone
Limited data suggest low amount excreted with low one time dosing.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest low amount excreted with low one time dosing. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Mifepristone
Renal-For CrCl<90ml/min, do not exceed 600 mg once daily Gastrointestinal-Risk of nausea, vomiting, diarrhea
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- Mifepristone may cause a loss of pregnancy. Before starting this medication, women of childbearing age must get a pregnancy test to confirm that they are not pregnant. Women must avoid becoming pregnant while taking this medication and for one month after stopping this medication.<br /><br />Consult your doctor for more details and to discuss using a reliable form of non-hormonal birth control (such as condoms, diaphragm with spermicide). If you become pregnant or think you may be pregnant, tell your doctor right away. If this medication is stopped for more than 14 days, women of childbearing age must get another pregnancy test to confirm that they are not pregnant before restarting the medication.
| Type 2 diabetes adjunct in cushing's syndrome | |
| E08 | Diabetes mellitus due to underlying condition |
| E08.0 | Diabetes mellitus due to underlying condition with hyperosmolarity |
| E08.00 | Diabetes mellitus due to underlying condition with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHc) |
| E08.01 | Diabetes mellitus due to underlying condition with hyperosmolarity with coma |
| E08.1 | Diabetes mellitus due to underlying condition with ketoacidosis |
| E08.10 | Diabetes mellitus due to underlying condition with ketoacidosis without coma |
| E08.11 | Diabetes mellitus due to underlying condition with ketoacidosis with coma |
| E08.2 | Diabetes mellitus due to underlying condition with kidney complications |
| E08.21 | Diabetes mellitus due to underlying condition with diabetic nephropathy |
| E08.22 | Diabetes mellitus due to underlying condition with diabetic chronic kidney disease |
| E08.29 | Diabetes mellitus due to underlying condition with other diabetic kidney complication |
| E08.3 | Diabetes mellitus due to underlying condition with ophthalmic complications |
| E08.31 | Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy |
| E08.311 | Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema |
| E08.319 | Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy without macular edema |
| E08.32 | Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy |
| E08.321 | Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema |
| E08.329 | Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema |
| E08.33 | Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy |
| E08.331 | Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema |
| E08.339 | Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy without macular edema |
| E08.34 | Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy |
| E08.341 | Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy with macular edema |
| E08.349 | Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy without macular edema |
| E08.35 | Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy |
| E08.351 | Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema |
| E08.359 | Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema |
| E08.36 | Diabetes mellitus due to underlying condition with diabetic cataract |
| E08.39 | Diabetes mellitus due to underlying condition with other diabetic ophthalmic complication |
| E08.4 | Diabetes mellitus due to underlying condition with neurological complications |
| E08.40 | Diabetes mellitus due to underlying condition with diabetic neuropathy, unspecified |
| E08.41 | Diabetes mellitus due to underlying condition with diabetic mononeuropathy |
| E08.42 | Diabetes mellitus due to underlying condition with diabetic polyneuropathy |
| E08.43 | Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy |
| E08.44 | Diabetes mellitus due to underlying condition with diabetic amyotrophy |
| E08.49 | Diabetes mellitus due to underlying condition with other diabetic neurological complication |
| E08.5 | Diabetes mellitus due to underlying condition with circulatory complications |
| E08.51 | Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy without gangrene |
| E08.52 | Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene |
| E08.59 | Diabetes mellitus due to underlying condition with other circulatory complications |
| E08.6 | Diabetes mellitus due to underlying condition with other specified complications |
| E08.61 | Diabetes mellitus due to underlying condition with diabetic arthropathy |
| E08.610 | Diabetes mellitus due to underlying condition with diabetic neuropathic arthropathy |
| E08.618 | Diabetes mellitus due to underlying condition with other diabetic arthropathy |
| E08.62 | Diabetes mellitus due to underlying condition with skin complications |
| E08.620 | Diabetes mellitus due to underlying condition with diabetic dermatitis |
| E08.621 | Diabetes mellitus due to underlying condition with foot ulcer |
| E08.622 | Diabetes mellitus due to underlying condition with other skin ulcer |
| E08.628 | Diabetes mellitus due to underlying condition with other skin complications |
| E08.63 | Diabetes mellitus due to underlying condition with oral complications |
| E08.630 | Diabetes mellitus due to underlying condition with periodontal disease |
| E08.638 | Diabetes mellitus due to underlying condition with other oral complications |
| E08.64 | Diabetes mellitus due to underlying condition with hypoglycemia |
| E08.641 | Diabetes mellitus due to underlying condition with hypoglycemia with coma |
| E08.649 | Diabetes mellitus due to underlying condition with hypoglycemia without coma |
| E08.65 | Diabetes mellitus due to underlying condition with hyperglycemia |
| E08.69 | Diabetes mellitus due to underlying condition with other specified complication |
| E08.8 | Diabetes mellitus due to underlying condition with unspecified complications |
| E08.9 | Diabetes mellitus due to underlying condition without complications |
| 0-9 | A-Z |
|---|---|
| E08 | Diabetes mellitus due to underlying condition |
| E08.0 | Diabetes mellitus due to underlying condition with hyperosmolarity |
| E08.00 | Diabetes mellitus due to underlying condition with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHc) |
| E08.01 | Diabetes mellitus due to underlying condition with hyperosmolarity with coma |
| E08.1 | Diabetes mellitus due to underlying condition with ketoacidosis |
| E08.10 | Diabetes mellitus due to underlying condition with ketoacidosis without coma |
| E08.11 | Diabetes mellitus due to underlying condition with ketoacidosis with coma |
| E08.2 | Diabetes mellitus due to underlying condition with kidney complications |
| E08.21 | Diabetes mellitus due to underlying condition with diabetic nephropathy |
| E08.22 | Diabetes mellitus due to underlying condition with diabetic chronic kidney disease |
| E08.29 | Diabetes mellitus due to underlying condition with other diabetic kidney complication |
| E08.3 | Diabetes mellitus due to underlying condition with ophthalmic complications |
| E08.31 | Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy |
| E08.311 | Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema |
| E08.319 | Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy without macular edema |
| E08.32 | Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy |
| E08.321 | Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema |
| E08.329 | Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema |
| E08.33 | Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy |
| E08.331 | Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema |
| E08.339 | Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy without macular edema |
| E08.34 | Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy |
| E08.341 | Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy with macular edema |
| E08.349 | Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy without macular edema |
| E08.35 | Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy |
| E08.351 | Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema |
| E08.359 | Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema |
| E08.36 | Diabetes mellitus due to underlying condition with diabetic cataract |
| E08.39 | Diabetes mellitus due to underlying condition with other diabetic ophthalmic complication |
| E08.4 | Diabetes mellitus due to underlying condition with neurological complications |
| E08.40 | Diabetes mellitus due to underlying condition with diabetic neuropathy, unspecified |
| E08.41 | Diabetes mellitus due to underlying condition with diabetic mononeuropathy |
| E08.42 | Diabetes mellitus due to underlying condition with diabetic polyneuropathy |
| E08.43 | Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy |
| E08.44 | Diabetes mellitus due to underlying condition with diabetic amyotrophy |
| E08.49 | Diabetes mellitus due to underlying condition with other diabetic neurological complication |
| E08.5 | Diabetes mellitus due to underlying condition with circulatory complications |
| E08.51 | Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy without gangrene |
| E08.52 | Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene |
| E08.59 | Diabetes mellitus due to underlying condition with other circulatory complications |
| E08.6 | Diabetes mellitus due to underlying condition with other specified complications |
| E08.61 | Diabetes mellitus due to underlying condition with diabetic arthropathy |
| E08.610 | Diabetes mellitus due to underlying condition with diabetic neuropathic arthropathy |
| E08.618 | Diabetes mellitus due to underlying condition with other diabetic arthropathy |
| E08.62 | Diabetes mellitus due to underlying condition with skin complications |
| E08.620 | Diabetes mellitus due to underlying condition with diabetic dermatitis |
| E08.621 | Diabetes mellitus due to underlying condition with foot ulcer |
| E08.622 | Diabetes mellitus due to underlying condition with other skin ulcer |
| E08.628 | Diabetes mellitus due to underlying condition with other skin complications |
| E08.63 | Diabetes mellitus due to underlying condition with oral complications |
| E08.630 | Diabetes mellitus due to underlying condition with periodontal disease |
| E08.638 | Diabetes mellitus due to underlying condition with other oral complications |
| E08.64 | Diabetes mellitus due to underlying condition with hypoglycemia |
| E08.641 | Diabetes mellitus due to underlying condition with hypoglycemia with coma |
| E08.649 | Diabetes mellitus due to underlying condition with hypoglycemia without coma |
| E08.65 | Diabetes mellitus due to underlying condition with hyperglycemia |
| E08.69 | Diabetes mellitus due to underlying condition with other specified complication |
| E08.8 | Diabetes mellitus due to underlying condition with unspecified complications |
| E08.9 | Diabetes mellitus due to underlying condition without complications |
Formulary Reference Tool