ERGOTAMINE-CAFFEINE (ERGOTAMINE TARTRATE/CAFFEINE)
- Migraine
- Vascular headache
- Cluster headache
- Cluster headache prevention
ergotamine 1 mg-caffeine 100 mg tablet
- 1 tablet by oral route at start of attack, followed by 1 tablet every 1/2 hour if needed, up to 6 tablets per attack
1 mg-100 mg tablet
- 1 tablet by oral route at start of attack, followed by 1 tablet every 1/2 hour if needed, up to 6 tablets per attack
Cluster headache
- 1 tablet by oral route at start of attack, followed by 1 tablet every 1/2 hour if needed, up to 6 tablets per attack
- 1 tablet by oral route once daily at bedtime
- 1 tablet by oral route once daily for 10 days at bedtime
- 1 tablet by oral route once daily at bedtime for 14 days
- 2 tablets by oral route once daily at bedtime
- 2 tablets by oral route once daily at bedtime for 10 days
- 2 tablets by oral route once daily at bedtime for 14 days
Migraine
- 1 tablet by oral route at start of attack, followed by 1 tablet every 1/2 hour if needed, up to 6 tablets per attack
Vascular headache
- 1 tablet by oral route at start of attack, followed by 1 tablet every 1/2 hour if needed, up to 6 tablets per attack
- almotriptan malate
- Alsuma
- Amerge
- amoxicil-clarithromy-lansopraz
- Aptivus
- atazanavir
- Atripla
- Axert
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- boceprevir
- clarithromycin
- conivaptan in 5 % dextrose
- Crixivan
- darunavir
- delavirdine
- dipyridamole
- efavirenz
- efavirenz-emtricitabin-tenofov
- eletriptan HBr
- elvitegr-cobicist-emtric-tenof
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- fosamprenavir
- Frova
- frovatriptan
- Imitrex
- Imitrex Statdose Kit Refill
- Imitrex Statdose Pen
- Incivek
- indinavir
- Invirase
- itraconazole
- Kaletra
- Ketek
- ketoconazole
- Korlym
- Lexiva
- lopinavir-ritonavir
- Maxalt
- Maxalt-mlt
- Mifeprex
- mifepristone
- naratriptan
- nefazodone
- nelfinavir
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Onmel
- posaconazole
- Prevpac
- Prezista
- Relpax
- Rescriptor
- Reyataz
- ritonavir
- rizatriptan
- saquinavir mesylate
- Sporanox
- Sporanox Pulsepak
- Stribild
- sumatriptan
- sumatriptan succinate
- Sumavel Dosepro
- Sustiva
- telaprevir
- telithromycin
- tipranavir
- Vaprisol
- Vfend
- Vfend Iv
- Victrelis
- Viracept
- voriconazole
- zolmitriptan
- Zomig
- Zomig Zmt
Contraindicated
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Adenocard
- Adenoscan
- adenosine
- adenosine (diagnostic)
- Bidil
- cimetidine
- Dilatrate-sr
- dopamine
- dopamine in D5W
- enzalutamide
- Heartburn Relief
- Imdur
- Isochron
- Isoditrate
- isosorbide dinitrate
- isosorbide mononitrate
- isosorbide-hydralazine
- Lexiscan
- Minitran
- Nitro-bid
- Nitro-dur
- Nitro-time
- nitroglycerin
- nitroglycerin in 5 % dextrose
- Nitrolingual
- Nitromist
- Nitrostat
- regadenoson
- Tagamet Hb
- Xtandi
Severe
Moderate
- fluvoxamine
- lithium carbonate
- lithium citrate
- Lithobid
- Luvox Cr
- 30 day risk period post-myocardial infarction
- Cerebral ischemia
- Coronary artery disease
- Disease of liver
- Ergot alkaloid toxicity
- Hypertension
- Kidney disease with reduction in GFR
- Lactating mother
- Peripheral ischemia
- Peripheral vascular disease
- Pregnancy
- Raynaud's phenomenon
- Sepsis
- Severe pruritus
- Thrombophlebitis
Contraindicated
- Necrotizing enterocolitis
- Peptic ulcer
- Pleural fibrosis
- Porphyria
- Pulmonary fibrosis
- Retroperitoneal fibrosis
Severe
Moderate
- Cardiac arrhythmia
- Diarrhea
- Hypertension
- Insomnia
- Renal disease with moderate to severe impairment
- Seizure disorder
- Severe hepatic disease
ERGOTAMINE-CAFFEINE (ERGOTAMINE TARTRATE/CAFFEINE)
- Migraine
- Vascular headache
- Cluster headache
- Cluster headache prevention
- Peripheral edema
- Diarrhea
- Dizziness
- Drowsy
- Gastrointestinal irritation
- Insomnia
- Nausea
- Nervousness
- Vomiting
- Xerostomia
More Frequent
Severe
Less Severe
- None
- Excitement
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute confusion
- Angina
- Cardiac arrhythmia
- Coronary artery spasm
- Extrasystoles
- Hypertension
- Hypotension
- Ischemic colitis
- Miosis
- Peripheral vasoconstriction
- Pleural fibrosis
- Pulmonary fibrosis
- Retroperitoneal fibrosis
- Valvular sclerosis
- Visual changes
Less Severe
- Agitation
- Hyperesthesia
- Hyperglycemia
- Irritability
- Nausea
- Nephrotoxicity
- Scotomata
- Symptoms of anxiety
- Tachycardia
- Tinnitus
- Tremor
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Caffeine
Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
- 1 Day – 364 Days
- Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
- Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
- 1 Years – 13 Years
- Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
- Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
Caffeine
- Severity Level:
C
- Additional Notes: Reports of miscarriage,poor fetal growth possibly assoc w/high doses of caffeine
Ergotamine Tartrate
- Severity Level:
X
- Additional Notes:
Contraindicated
Ergotamine
Adverse effects reported in neonates
General | Excretion Potential | Effect on Infant | Notes |
Drug should not be given to breast feeding mothers | Excreted | Drug shown to have adverse effect | Adverse effects reported in neonates |
Precaution Exists
Caffeine
High doses may cause hyperactivity and wakefulness in infant.
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Drug shown to have adverse effect | High doses may cause hyperactivity and wakefulness in infant. |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Ergotamine Tartrate
Cardiovascular-More likely to experience complications such as induced hypothermia and ischemia.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: Y HEDIS: N STOPP: N
No Known Risk
None
- This medication has rarely caused a serious lack of blood flow to the arms/hands, or to the feet, or to the brain, which could cause a stroke. The risk is increased when this medication is taken with other drugs that can affect the removal of ergotamine from your body. Examples include boceprevir, mifepristone, telaprevir, telithromycin, certain antidepressants (such as nefazodone), azole antifungals (such as ketoconazole, itraconazole), cobicistat, macrolide antibiotics (such as clarithromycin, erythromycin, troleandomycin), HIV protease inhibitors (such as ritonavir, nelfinavir, indinavir), HIV NNRTIs (such as delavirdine), SSRIs (such as fluoxetine, paroxetine, fluvoxamine), among others.
Cluster headache | |
G44.00 | Cluster headache syndrome, unspecified |
G44.001 | Cluster headache syndrome, unspecified, intractable |
G44.009 | Cluster headache syndrome, unspecified, not intractable |
G44.01 | Episodic cluster headache |
G44.011 | Episodic cluster headache, intractable |
G44.019 | Episodic cluster headache, not intractable |
G44.02 | Chronic cluster headache |
G44.021 | Chronic cluster headache, intractable |
G44.029 | Chronic cluster headache, not intractable |
Cluster headache prevention | |
G44.00 | Cluster headache syndrome, unspecified |
G44.001 | Cluster headache syndrome, unspecified, intractable |
G44.009 | Cluster headache syndrome, unspecified, not intractable |
G44.01 | Episodic cluster headache |
G44.011 | Episodic cluster headache, intractable |
G44.019 | Episodic cluster headache, not intractable |
G44.02 | Chronic cluster headache |
G44.021 | Chronic cluster headache, intractable |
G44.029 | Chronic cluster headache, not intractable |
Migraine | |
G43 | Migraine |
G43.0 | Migraine without aura |
G43.00 | Migraine without aura, not intractable |
G43.001 | Migraine without aura, not intractable, with status migrainosus |
G43.009 | Migraine without aura, not intractable, without status migrainosus |
G43.01 | Migraine without aura, intractable |
G43.011 | Migraine without aura, intractable, with status migrainosus |
G43.019 | Migraine without aura, intractable, without status migrainosus |
G43.1 | Migraine with aura |
G43.10 | Migraine with aura, not intractable |
G43.101 | Migraine with aura, not intractable, with status migrainosus |
G43.109 | Migraine with aura, not intractable, without status migrainosus |
G43.11 | Migraine with aura, intractable |
G43.111 | Migraine with aura, intractable, with status migrainosus |
G43.119 | Migraine with aura, intractable, without status migrainosus |
G43.4 | Hemiplegic migraine |
G43.40 | Hemiplegic migraine, not intractable |
G43.41 | Hemiplegic migraine, intractable |
G43.7 | Chronic migraine without aura |
G43.70 | Chronic migraine without aura, not intractable |
G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
G43.71 | Chronic migraine without aura, intractable |
G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
G43.8 | Other migraine |
G43.80 | Other migraine, not intractable |
G43.801 | Other migraine, not intractable, with status migrainosus |
G43.809 | Other migraine, not intractable, without status migrainosus |
G43.81 | Other migraine, intractable |
G43.811 | Other migraine, intractable, with status migrainosus |
G43.819 | Other migraine, intractable, without status migrainosus |
G43.82 | Menstrual migraine, not intractable |
G43.821 | Menstrual migraine, not intractable, with status migrainosus |
G43.829 | Menstrual migraine, not intractable, without status migrainosus |
G43.83 | Menstrual migraine, intractable |
G43.831 | Menstrual migraine, intractable, with status migrainosus |
G43.839 | Menstrual migraine, intractable, without status migrainosus |
G43.9 | Migraine, unspecified |
G43.90 | Migraine, unspecified, not intractable |
G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
G43.91 | Migraine, unspecified, intractable |
G43.911 | Migraine, unspecified, intractable, with status migrainosus |
G43.919 | Migraine, unspecified, intractable, without status migrainosus |
G43.B | Ophthalmoplegic migraine |
G43.B0 | Ophthalmoplegic migraine, not intractable |
G43.B1 | Ophthalmoplegic migraine, intractable |
G43.C | Periodic headache syndromes in child or adult |
G43.C0 | Periodic headache syndromes in child or adult, not intractable |
G43.C1 | Periodic headache syndromes in child or adult, intractable |
G43.D | Abdominal migraine |
G43.D0 | Abdominal migraine, not intractable |
G43.D1 | Abdominal migraine, intractable |
Vascular headache | |
G43 | Migraine |
G43.0 | Migraine without aura |
G43.00 | Migraine without aura, not intractable |
G43.001 | Migraine without aura, not intractable, with status migrainosus |
G43.009 | Migraine without aura, not intractable, without status migrainosus |
G43.01 | Migraine without aura, intractable |
G43.011 | Migraine without aura, intractable, with status migrainosus |
G43.019 | Migraine without aura, intractable, without status migrainosus |
G43.1 | Migraine with aura |
G43.10 | Migraine with aura, not intractable |
G43.101 | Migraine with aura, not intractable, with status migrainosus |
G43.109 | Migraine with aura, not intractable, without status migrainosus |
G43.11 | Migraine with aura, intractable |
G43.111 | Migraine with aura, intractable, with status migrainosus |
G43.119 | Migraine with aura, intractable, without status migrainosus |
G43.4 | Hemiplegic migraine |
G43.40 | Hemiplegic migraine, not intractable |
G43.401 | Hemiplegic migraine, not intractable, with status migrainosus |
G43.409 | Hemiplegic migraine, not intractable, without status migrainosus |
G43.41 | Hemiplegic migraine, intractable |
G43.411 | Hemiplegic migraine, intractable, with status migrainosus |
G43.419 | Hemiplegic migraine, intractable, without status migrainosus |
G43.5 | Persistent migraine aura without cerebral infarction |
G43.50 | Persistent migraine aura without cerebral infarction, not intractable |
G43.501 | Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus |
G43.509 | Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus |
G43.51 | Persistent migraine aura without cerebral infarction, intractable |
G43.511 | Persistent migraine aura without cerebral infarction, intractable, with status migrainosus |
G43.519 | Persistent migraine aura without cerebral infarction, intractable, without status migrainosus |
G43.7 | Chronic migraine without aura |
G43.70 | Chronic migraine without aura, not intractable |
G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
G43.71 | Chronic migraine without aura, intractable |
G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
G43.8 | Other migraine |
G43.80 | Other migraine, not intractable |
G43.801 | Other migraine, not intractable, with status migrainosus |
G43.809 | Other migraine, not intractable, without status migrainosus |
G43.81 | Other migraine, intractable |
G43.811 | Other migraine, intractable, with status migrainosus |
G43.819 | Other migraine, intractable, without status migrainosus |
G43.82 | Menstrual migraine, not intractable |
G43.821 | Menstrual migraine, not intractable, with status migrainosus |
G43.829 | Menstrual migraine, not intractable, without status migrainosus |
G43.83 | Menstrual migraine, intractable |
G43.831 | Menstrual migraine, intractable, with status migrainosus |
G43.839 | Menstrual migraine, intractable, without status migrainosus |
G43.9 | Migraine, unspecified |
G43.90 | Migraine, unspecified, not intractable |
G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
G43.91 | Migraine, unspecified, intractable |
G43.911 | Migraine, unspecified, intractable, with status migrainosus |
G43.919 | Migraine, unspecified, intractable, without status migrainosus |
G43.B | Ophthalmoplegic migraine |
G43.B0 | Ophthalmoplegic migraine, not intractable |
G43.B1 | Ophthalmoplegic migraine, intractable |
G43.C | Periodic headache syndromes in child or adult |
G43.C0 | Periodic headache syndromes in child or adult, not intractable |
G43.C1 | Periodic headache syndromes in child or adult, intractable |
G44.1 | Vascular headache, not elsewhere classified |
G96.9 | Disorder of central nervous system, unspecified |
0-9 | A-Z |
---|---|
G43 | Migraine |
G43 | Migraine |
G43.0 | Migraine without aura |
G43.0 | Migraine without aura |
G43.00 | Migraine without aura, not intractable |
G43.00 | Migraine without aura, not intractable |
G43.001 | Migraine without aura, not intractable, with status migrainosus |
G43.001 | Migraine without aura, not intractable, with status migrainosus |
G43.009 | Migraine without aura, not intractable, without status migrainosus |
G43.009 | Migraine without aura, not intractable, without status migrainosus |
G43.01 | Migraine without aura, intractable |
G43.01 | Migraine without aura, intractable |
G43.011 | Migraine without aura, intractable, with status migrainosus |
G43.011 | Migraine without aura, intractable, with status migrainosus |
G43.019 | Migraine without aura, intractable, without status migrainosus |
G43.019 | Migraine without aura, intractable, without status migrainosus |
G43.1 | Migraine with aura |
G43.1 | Migraine with aura |
G43.10 | Migraine with aura, not intractable |
G43.10 | Migraine with aura, not intractable |
G43.101 | Migraine with aura, not intractable, with status migrainosus |
G43.101 | Migraine with aura, not intractable, with status migrainosus |
G43.109 | Migraine with aura, not intractable, without status migrainosus |
G43.109 | Migraine with aura, not intractable, without status migrainosus |
G43.11 | Migraine with aura, intractable |
G43.11 | Migraine with aura, intractable |
G43.111 | Migraine with aura, intractable, with status migrainosus |
G43.111 | Migraine with aura, intractable, with status migrainosus |
G43.119 | Migraine with aura, intractable, without status migrainosus |
G43.119 | Migraine with aura, intractable, without status migrainosus |
G43.4 | Hemiplegic migraine |
G43.4 | Hemiplegic migraine |
G43.40 | Hemiplegic migraine, not intractable |
G43.40 | Hemiplegic migraine, not intractable |
G43.401 | Hemiplegic migraine, not intractable, with status migrainosus |
G43.409 | Hemiplegic migraine, not intractable, without status migrainosus |
G43.41 | Hemiplegic migraine, intractable |
G43.41 | Hemiplegic migraine, intractable |
G43.411 | Hemiplegic migraine, intractable, with status migrainosus |
G43.419 | Hemiplegic migraine, intractable, without status migrainosus |
G43.5 | Persistent migraine aura without cerebral infarction |
G43.50 | Persistent migraine aura without cerebral infarction, not intractable |
G43.501 | Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus |
G43.509 | Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus |
G43.51 | Persistent migraine aura without cerebral infarction, intractable |
G43.511 | Persistent migraine aura without cerebral infarction, intractable, with status migrainosus |
G43.519 | Persistent migraine aura without cerebral infarction, intractable, without status migrainosus |
G43.7 | Chronic migraine without aura |
G43.7 | Chronic migraine without aura |
G43.70 | Chronic migraine without aura, not intractable |
G43.70 | Chronic migraine without aura, not intractable |
G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
G43.71 | Chronic migraine without aura, intractable |
G43.71 | Chronic migraine without aura, intractable |
G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
G43.8 | Other migraine |
G43.8 | Other migraine |
G43.80 | Other migraine, not intractable |
G43.80 | Other migraine, not intractable |
G43.801 | Other migraine, not intractable, with status migrainosus |
G43.801 | Other migraine, not intractable, with status migrainosus |
G43.809 | Other migraine, not intractable, without status migrainosus |
G43.809 | Other migraine, not intractable, without status migrainosus |
G43.81 | Other migraine, intractable |
G43.81 | Other migraine, intractable |
G43.811 | Other migraine, intractable, with status migrainosus |
G43.811 | Other migraine, intractable, with status migrainosus |
G43.819 | Other migraine, intractable, without status migrainosus |
G43.819 | Other migraine, intractable, without status migrainosus |
G43.82 | Menstrual migraine, not intractable |
G43.82 | Menstrual migraine, not intractable |
G43.821 | Menstrual migraine, not intractable, with status migrainosus |
G43.821 | Menstrual migraine, not intractable, with status migrainosus |
G43.829 | Menstrual migraine, not intractable, without status migrainosus |
G43.829 | Menstrual migraine, not intractable, without status migrainosus |
G43.83 | Menstrual migraine, intractable |
G43.83 | Menstrual migraine, intractable |
G43.831 | Menstrual migraine, intractable, with status migrainosus |
G43.831 | Menstrual migraine, intractable, with status migrainosus |
G43.839 | Menstrual migraine, intractable, without status migrainosus |
G43.839 | Menstrual migraine, intractable, without status migrainosus |
G43.9 | Migraine, unspecified |
G43.9 | Migraine, unspecified |
G43.90 | Migraine, unspecified, not intractable |
G43.90 | Migraine, unspecified, not intractable |
G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
G43.91 | Migraine, unspecified, intractable |
G43.91 | Migraine, unspecified, intractable |
G43.911 | Migraine, unspecified, intractable, with status migrainosus |
G43.911 | Migraine, unspecified, intractable, with status migrainosus |
G43.919 | Migraine, unspecified, intractable, without status migrainosus |
G43.919 | Migraine, unspecified, intractable, without status migrainosus |
G43.B | Ophthalmoplegic migraine |
G43.B | Ophthalmoplegic migraine |
G43.B0 | Ophthalmoplegic migraine, not intractable |
G43.B0 | Ophthalmoplegic migraine, not intractable |
G43.B1 | Ophthalmoplegic migraine, intractable |
G43.B1 | Ophthalmoplegic migraine, intractable |
G43.C | Periodic headache syndromes in child or adult |
G43.C | Periodic headache syndromes in child or adult |
G43.C0 | Periodic headache syndromes in child or adult, not intractable |
G43.C0 | Periodic headache syndromes in child or adult, not intractable |
G43.C1 | Periodic headache syndromes in child or adult, intractable |
G43.C1 | Periodic headache syndromes in child or adult, intractable |
G43.D | Abdominal migraine |
G43.D0 | Abdominal migraine, not intractable |
G43.D1 | Abdominal migraine, intractable |
G44.00 | Cluster headache syndrome, unspecified |
G44.00 | Cluster headache syndrome, unspecified |
G44.001 | Cluster headache syndrome, unspecified, intractable |
G44.001 | Cluster headache syndrome, unspecified, intractable |
G44.009 | Cluster headache syndrome, unspecified, not intractable |
G44.009 | Cluster headache syndrome, unspecified, not intractable |
G44.01 | Episodic cluster headache |
G44.01 | Episodic cluster headache |
G44.011 | Episodic cluster headache, intractable |
G44.011 | Episodic cluster headache, intractable |
G44.019 | Episodic cluster headache, not intractable |
G44.019 | Episodic cluster headache, not intractable |
G44.02 | Chronic cluster headache |
G44.02 | Chronic cluster headache |
G44.021 | Chronic cluster headache, intractable |
G44.021 | Chronic cluster headache, intractable |
G44.029 | Chronic cluster headache, not intractable |
G44.029 | Chronic cluster headache, not intractable |
G44.1 | Vascular headache, not elsewhere classified |
G96.9 | Disorder of central nervous system, unspecified |