REST SIMPLY (DIPHENHYDRAMINE HCL)
- Allergic reaction
- Insomnia
- Allergic conjunctivitis
- Allergic rhinitis
- Anaphylaxis
- Cough
- Dermatographic urticaria
- Idiopathic parkinsonism
- Motion sickness
- Nasal congestion
- Nausea
- Nausea and vomiting
- Parkinsonism
- Pruritus of skin
- Sneezing
- Urticaria
- Vertigo
- Vomiting
- Sominex Tablet
- Sleep-tabs Tablet
- Sleep Tablet (diphenhydramine) Tablet
- Sleep Ii Tablet
- Sleep Aid (diphenhydramine) Tablet
- Simply Sleep Tablet
- Rest Simply Nighttime Sleep Tablet
- Nytol Tablet
- Nighttime Sleep Aid (diphenhydramine) Tablet
- Alka-seltzer Plus Allergy Tablet
- By Indication
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
Sleep-Tabs 25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
Sleep Tablet (diphenhydramine) 25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
(diphenhydramine) 25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
Nighttime Sleep 25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
Nytol 25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
(diphenhydramine) 25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
NightTime Sleep Aid (diphenhydramine) 25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
25 mg tablet
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
Default screening record
- 1 tablet (25 mg) by oral route 3 times per day
- 1 tablet (25 mg) by oral route 4 times per day
- 1 tablet (25 mg) by oral route every 4 hours as needed
- 1 tablet (25 mg) by oral route every 6 hours as needed
- 1 tablet (25 mg) by oral route every 4-6 hours as needed
- 1 tablet (25 mg) by oral route every 4-6 hours
- 1 tablet (25 mg) by oral route every 8 hours
- 1 tablet (25 mg) by oral route every 6-8 hours
- 1 tablet (25 mg) by oral route every 4-8 hours
- 1 tablet (25 mg) by oral route every 6 hours
- 1 tablet (25 mg) by oral route every 4 hours
- 2 tablets (50 mg) by oral route every 6 hours
- 2 tablets (50 mg) by oral route every 4 hours
- 2 tablets (50 mg) by oral route every 4-6 hours as needed
- 2 tablets (50 mg) by oral route 20-30 minutes before bedtime if needed
- 2 tablets (50 mg) by oral route once daily at bedtime as needed
- 2 tablets (50 mg) by oral route every 4-8 hours
- 2 tablets (50 mg) by oral route every 6-8 hours
- 2 tablets (50 mg) by oral route every 8 hours
- 2 tablets (50 mg) by oral route every 4 hours as needed
- 2 tablets (50 mg) by oral route every 6 hours as needed
- 2 tablets (50 mg) by oral route 3 times per day
- 2 tablets (50 mg) by oral route 4 times per day
- None
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- None
Severe
Moderate
- None
REST SIMPLY (DIPHENHYDRAMINE HCL)
- Allergic reaction
- Insomnia
- Allergic conjunctivitis
- Allergic rhinitis
- Anaphylaxis
- Cough
- Dermatographic urticaria
- Idiopathic parkinsonism
- Motion sickness
- Nasal congestion
- Nausea
- Nausea and vomiting
- Parkinsonism
- Pruritus of skin
- Sneezing
- Urticaria
- Vertigo
- Vomiting
- None
- None
More Frequent
Severe
Less Severe
- None
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- None
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Diphenhydramine
- Severity Level:
B
- Additional Notes:
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
None
General | Excretion Potential | Effect on Infant | Notes |
None |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Diphenhydramine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Maximum of 25mg/day. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | N | N | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- None
Allergic conjunctivitis | |
H10.1 | Acute atopic conjunctivitis |
H10.10 | Acute atopic conjunctivitis, unspecified eye |
H10.11 | Acute atopic conjunctivitis, right eye |
H10.12 | Acute atopic conjunctivitis, left eye |
H10.13 | Acute atopic conjunctivitis, bilateral |
H10.44 | Vernal conjunctivitis |
H10.45 | Other chronic allergic conjunctivitis |
H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
Allergic reaction | |
T78.40 | Allergy, unspecified |
T78.40xA | Allergy, unspecified, initial encounter |
Allergic rhinitis | |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
Anaphylaxis | |
T78.0 | Anaphylactic reaction due to food |
T78.00 | Anaphylactic reaction due to unspecified food |
T78.00xA | Anaphylactic reaction due to unspecified food, initial encounter |
T78.01 | Anaphylactic reaction due to peanuts |
T78.01xA | Anaphylactic reaction due to peanuts, initial encounter |
T78.02 | Anaphylactic reaction due to shellfish (crustaceans) |
T78.02xA | Anaphylactic reaction due to shellfish (crustaceans), initial encounter |
T78.03 | Anaphylactic reaction due to other fish |
T78.03xA | Anaphylactic reaction due to other fish, initial encounter |
T78.04 | Anaphylactic reaction due to fruits and vegetables |
T78.04xA | Anaphylactic reaction due to fruits and vegetables, initial encounter |
T78.05 | Anaphylactic reaction due to tree nuts and seeds |
T78.05xA | Anaphylactic reaction due to tree nuts and seeds, initial encounter |
T78.06 | Anaphylactic reaction due to food additives |
T78.06xA | Anaphylactic reaction due to food additives, initial encounter |
T78.07 | Anaphylactic reaction due to milk and dairy products |
T78.07xA | Anaphylactic reaction due to milk and dairy products, initial encounter |
T78.08 | Anaphylactic reaction due to eggs |
T78.08xA | Anaphylactic reaction due to eggs, initial encounter |
T78.09 | Anaphylactic reaction due to other food products |
T78.09xA | Anaphylactic reaction due to other food products, initial encounter |
T78.2 | Anaphylactic shock, unspecified |
T78.2xxA | Anaphylactic shock, unspecified, initial encounter |
T80.5 | Anaphylactic reaction due to serum |
T80.51 | Anaphylactic reaction due to administration of blood and blood products |
T80.51xA | Anaphylactic reaction due to administration of blood and blood products, initial encounter |
T80.52 | Anaphylactic reaction due to vaccination |
T80.52xA | Anaphylactic reaction due to vaccination, initial encounter |
T80.59 | Anaphylactic reaction due to other serum |
T80.59xA | Anaphylactic reaction due to other serum, initial encounter |
T88.6 | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered |
T88.6xxA | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter |
Cough | |
R05 | Cough |
R05.1 | Acute cough |
R05.2 | Subacute cough |
R05.3 | Chronic cough |
R05.9 | Cough, unspecified |
Dermatographic urticaria | |
L50.3 | Dermatographic urticaria |
Idiopathic parkinsonism | |
G20 | Parkinson's disease |
G20.A | Parkinson's disease without dyskinesia |
G20.A1 | Parkinson's disease without dyskinesia, without mention of fluctuations |
G20.A2 | Parkinson's disease without dyskinesia, with fluctuations |
G20.B | Parkinson's disease with dyskinesia |
G20.B1 | Parkinson's disease with dyskinesia, without mention of fluctuations |
G20.B2 | Parkinson's disease with dyskinesia, with fluctuations |
G20.C | Parkinsonism, unspecified |
Insomnia | |
F51.0 | Insomnia not due to a substance or known physiological condition |
F51.01 | Primary insomnia |
F51.02 | Adjustment insomnia |
F51.03 | Paradoxical insomnia |
F51.04 | Psychophysiologic insomnia |
F51.05 | Insomnia due to other mental disorder |
F51.09 | Other insomnia not due to a substance or known physiological condition |
G47.0 | Insomnia |
G47.00 | Insomnia, unspecified |
G47.01 | Insomnia due to medical condition |
G47.09 | Other insomnia |
Motion sickness | |
T75.3xxA | Motion sickness, initial encounter |
Nasal congestion | |
R09.81 | Nasal congestion |
Nausea | |
R11 | Nausea and vomiting |
R11.0 | Nausea |
R11.2 | Nausea with vomiting, unspecified |
Nausea and vomiting | |
R11 | Nausea and vomiting |
R11.2 | Nausea with vomiting, unspecified |
Parkinsonism | |
G20 | Parkinson's disease |
G20.A | Parkinson's disease without dyskinesia |
G20.A1 | Parkinson's disease without dyskinesia, without mention of fluctuations |
G20.A2 | Parkinson's disease without dyskinesia, with fluctuations |
G20.B | Parkinson's disease with dyskinesia |
G20.B1 | Parkinson's disease with dyskinesia, without mention of fluctuations |
G20.B2 | Parkinson's disease with dyskinesia, with fluctuations |
G20.C | Parkinsonism, unspecified |
G21 | Secondary parkinsonism |
G21.2 | Secondary parkinsonism due to other external agents |
G21.3 | Postencephalitic parkinsonism |
G21.4 | Vascular parkinsonism |
G21.8 | Other secondary parkinsonism |
G21.9 | Secondary parkinsonism, unspecified |
Pruritus of skin | |
L29.8 | Other pruritus |
L29.9 | Pruritus, unspecified |
Sneezing | |
R06.7 | Sneezing |
Urticaria | |
L50 | Urticaria |
L50.0 | Allergic urticaria |
L50.1 | Idiopathic urticaria |
L50.2 | Urticaria due to cold and heat |
L50.3 | Dermatographic urticaria |
L50.4 | Vibratory urticaria |
L50.5 | Cholinergic urticaria |
L50.6 | Contact urticaria |
L50.8 | Other urticaria |
L50.9 | Urticaria, unspecified |
L56.3 | Solar urticaria |
O26.86 | Pruritic urticarial papules and plaques of pregnancy (PUPPp) |
Vertigo | |
A88.1 | Epidemic vertigo |
H81.1 | Benign paroxysmal vertigo |
H81.10 | Benign paroxysmal vertigo, unspecified ear |
H81.11 | Benign paroxysmal vertigo, right ear |
H81.12 | Benign paroxysmal vertigo, left ear |
H81.13 | Benign paroxysmal vertigo, bilateral |
H81.2 | Vestibular neuronitis |
H81.20 | Vestibular neuronitis, unspecified ear |
H81.21 | Vestibular neuronitis, right ear |
H81.22 | Vestibular neuronitis, left ear |
H81.23 | Vestibular neuronitis, bilateral |
H81.3 | Other peripheral vertigo |
H81.31 | Aural vertigo |
H81.311 | Aural vertigo, right ear |
H81.312 | Aural vertigo, left ear |
H81.313 | Aural vertigo, bilateral |
H81.319 | Aural vertigo, unspecified ear |
H81.39 | Other peripheral vertigo |
H81.391 | Other peripheral vertigo, right ear |
H81.392 | Other peripheral vertigo, left ear |
H81.393 | Other peripheral vertigo, bilateral |
H81.399 | Other peripheral vertigo, unspecified ear |
H81.4 | Vertigo of central origin |
H82 | Vertiginous syndromes in diseases classified elsewhere |
H82.1 | Vertiginous syndromes in diseases classified elsewhere, right ear |
H82.2 | Vertiginous syndromes in diseases classified elsewhere, left ear |
H82.3 | Vertiginous syndromes in diseases classified elsewhere, bilateral |
H82.9 | Vertiginous syndromes in diseases classified elsewhere, unspecified ear |
R42 | Dizziness and giddiness |
T75.23 | Vertigo from infrasound |
T75.23xA | Vertigo from infrasound, initial encounter |
Vomiting | |
K91.0 | Vomiting following gastrointestinal surgery |
R11 | Nausea and vomiting |
R11.1 | Vomiting |
R11.10 | Vomiting, unspecified |
R11.11 | Vomiting without nausea |
R11.12 | Projectile vomiting |
R11.13 | Vomiting of fecal matter |
R11.14 | Bilious vomiting |
R11.15 | Cyclical vomiting syndrome unrelated to migraine |
R11.2 | Nausea with vomiting, unspecified |
0-9 | A-Z |
---|---|
A88.1 | Epidemic vertigo |
F51.0 | Insomnia not due to a substance or known physiological condition |
F51.01 | Primary insomnia |
F51.02 | Adjustment insomnia |
F51.03 | Paradoxical insomnia |
F51.04 | Psychophysiologic insomnia |
F51.05 | Insomnia due to other mental disorder |
F51.09 | Other insomnia not due to a substance or known physiological condition |
G20 | Parkinson's disease |
G20 | Parkinson's disease |
G20.A | Parkinson's disease without dyskinesia |
G20.A | Parkinson's disease without dyskinesia |
G20.A1 | Parkinson's disease without dyskinesia, without mention of fluctuations |
G20.A1 | Parkinson's disease without dyskinesia, without mention of fluctuations |
G20.A2 | Parkinson's disease without dyskinesia, with fluctuations |
G20.A2 | Parkinson's disease without dyskinesia, with fluctuations |
G20.B | Parkinson's disease with dyskinesia |
G20.B | Parkinson's disease with dyskinesia |
G20.B1 | Parkinson's disease with dyskinesia, without mention of fluctuations |
G20.B1 | Parkinson's disease with dyskinesia, without mention of fluctuations |
G20.B2 | Parkinson's disease with dyskinesia, with fluctuations |
G20.B2 | Parkinson's disease with dyskinesia, with fluctuations |
G20.C | Parkinsonism, unspecified |
G20.C | Parkinsonism, unspecified |
G21 | Secondary parkinsonism |
G21.2 | Secondary parkinsonism due to other external agents |
G21.3 | Postencephalitic parkinsonism |
G21.4 | Vascular parkinsonism |
G21.8 | Other secondary parkinsonism |
G21.9 | Secondary parkinsonism, unspecified |
G47.0 | Insomnia |
G47.00 | Insomnia, unspecified |
G47.01 | Insomnia due to medical condition |
G47.09 | Other insomnia |
H10.1 | Acute atopic conjunctivitis |
H10.10 | Acute atopic conjunctivitis, unspecified eye |
H10.11 | Acute atopic conjunctivitis, right eye |
H10.12 | Acute atopic conjunctivitis, left eye |
H10.13 | Acute atopic conjunctivitis, bilateral |
H10.44 | Vernal conjunctivitis |
H10.45 | Other chronic allergic conjunctivitis |
H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
H81.1 | Benign paroxysmal vertigo |
H81.10 | Benign paroxysmal vertigo, unspecified ear |
H81.11 | Benign paroxysmal vertigo, right ear |
H81.12 | Benign paroxysmal vertigo, left ear |
H81.13 | Benign paroxysmal vertigo, bilateral |
H81.2 | Vestibular neuronitis |
H81.20 | Vestibular neuronitis, unspecified ear |
H81.21 | Vestibular neuronitis, right ear |
H81.22 | Vestibular neuronitis, left ear |
H81.23 | Vestibular neuronitis, bilateral |
H81.3 | Other peripheral vertigo |
H81.31 | Aural vertigo |
H81.311 | Aural vertigo, right ear |
H81.312 | Aural vertigo, left ear |
H81.313 | Aural vertigo, bilateral |
H81.319 | Aural vertigo, unspecified ear |
H81.39 | Other peripheral vertigo |
H81.391 | Other peripheral vertigo, right ear |
H81.392 | Other peripheral vertigo, left ear |
H81.393 | Other peripheral vertigo, bilateral |
H81.399 | Other peripheral vertigo, unspecified ear |
H81.4 | Vertigo of central origin |
H82 | Vertiginous syndromes in diseases classified elsewhere |
H82.1 | Vertiginous syndromes in diseases classified elsewhere, right ear |
H82.2 | Vertiginous syndromes in diseases classified elsewhere, left ear |
H82.3 | Vertiginous syndromes in diseases classified elsewhere, bilateral |
H82.9 | Vertiginous syndromes in diseases classified elsewhere, unspecified ear |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
K91.0 | Vomiting following gastrointestinal surgery |
L29.8 | Other pruritus |
L29.9 | Pruritus, unspecified |
L50 | Urticaria |
L50.0 | Allergic urticaria |
L50.1 | Idiopathic urticaria |
L50.2 | Urticaria due to cold and heat |
L50.3 | Dermatographic urticaria |
L50.3 | Dermatographic urticaria |
L50.4 | Vibratory urticaria |
L50.5 | Cholinergic urticaria |
L50.6 | Contact urticaria |
L50.8 | Other urticaria |
L50.9 | Urticaria, unspecified |
L56.3 | Solar urticaria |
O26.86 | Pruritic urticarial papules and plaques of pregnancy (PUPPp) |
R05 | Cough |
R05.1 | Acute cough |
R05.2 | Subacute cough |
R05.3 | Chronic cough |
R05.9 | Cough, unspecified |
R06.7 | Sneezing |
R09.81 | Nasal congestion |
R11 | Nausea and vomiting |
R11 | Nausea and vomiting |
R11 | Nausea and vomiting |
R11.0 | Nausea |
R11.1 | Vomiting |
R11.10 | Vomiting, unspecified |
R11.11 | Vomiting without nausea |
R11.12 | Projectile vomiting |
R11.13 | Vomiting of fecal matter |
R11.14 | Bilious vomiting |
R11.15 | Cyclical vomiting syndrome unrelated to migraine |
R11.2 | Nausea with vomiting, unspecified |
R11.2 | Nausea with vomiting, unspecified |
R11.2 | Nausea with vomiting, unspecified |
R42 | Dizziness and giddiness |
T75.23 | Vertigo from infrasound |
T75.23xA | Vertigo from infrasound, initial encounter |
T75.3xxA | Motion sickness, initial encounter |
T78.0 | Anaphylactic reaction due to food |
T78.00 | Anaphylactic reaction due to unspecified food |
T78.00xA | Anaphylactic reaction due to unspecified food, initial encounter |
T78.01 | Anaphylactic reaction due to peanuts |
T78.01xA | Anaphylactic reaction due to peanuts, initial encounter |
T78.02 | Anaphylactic reaction due to shellfish (crustaceans) |
T78.02xA | Anaphylactic reaction due to shellfish (crustaceans), initial encounter |
T78.03 | Anaphylactic reaction due to other fish |
T78.03xA | Anaphylactic reaction due to other fish, initial encounter |
T78.04 | Anaphylactic reaction due to fruits and vegetables |
T78.04xA | Anaphylactic reaction due to fruits and vegetables, initial encounter |
T78.05 | Anaphylactic reaction due to tree nuts and seeds |
T78.05xA | Anaphylactic reaction due to tree nuts and seeds, initial encounter |
T78.06 | Anaphylactic reaction due to food additives |
T78.06xA | Anaphylactic reaction due to food additives, initial encounter |
T78.07 | Anaphylactic reaction due to milk and dairy products |
T78.07xA | Anaphylactic reaction due to milk and dairy products, initial encounter |
T78.08 | Anaphylactic reaction due to eggs |
T78.08xA | Anaphylactic reaction due to eggs, initial encounter |
T78.09 | Anaphylactic reaction due to other food products |
T78.09xA | Anaphylactic reaction due to other food products, initial encounter |
T78.2 | Anaphylactic shock, unspecified |
T78.2xxA | Anaphylactic shock, unspecified, initial encounter |
T78.40 | Allergy, unspecified |
T78.40xA | Allergy, unspecified, initial encounter |
T80.5 | Anaphylactic reaction due to serum |
T80.51 | Anaphylactic reaction due to administration of blood and blood products |
T80.51xA | Anaphylactic reaction due to administration of blood and blood products, initial encounter |
T80.52 | Anaphylactic reaction due to vaccination |
T80.52xA | Anaphylactic reaction due to vaccination, initial encounter |
T80.59 | Anaphylactic reaction due to other serum |
T80.59xA | Anaphylactic reaction due to other serum, initial encounter |
T88.6 | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered |
T88.6xxA | Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered, initial encounter |