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VIRAMUNE (NEVIRAPINE)
- HIV infection
200 mg tablet
- 1 tablet (200 mg) by oral route once daily
50 mg/5 mL oral suspension
- 20 milliliters (200 mg) by oral route once daily
200 mg tablet
- 1 tablet (200 mg) by oral route once daily
50 mg/5 mL oral suspension
- 20 milliliters (200 mg) by oral route once daily
HIV infection
- 20 milliliters (200 mg) by oral route once daily
- 1 tablet (200 mg) by oral route once daily
- 1 tablet (200 mg) by oral route 2 times per day
- 1 tablet (200 mg) by oral route every 12 hours
- 1 tablet (200 mg) by oral route every 24 hours
- 1 tablet (200 mg) by oral route once daily for 14 days
- 1 tablet (200 mg) by oral route every 24 hours for 14 days
- 20 milliliters (200 mg) by oral route once daily for 14 days
- 20 milliliters (200 mg) by oral route every 24 hours for 14 days
- 20 milliliters (200 mg) by oral route every 24 hours
- 20 milliliters (200 mg) by oral route 2 times per day
- 20 milliliters (200 mg) by oral route every 12 hours
- atazanavir
- B cplx-C-St.Johnwrt-K.&S.ginsg
- calcium-mag-B complex-D3-hrb61
- Cold & Flu Fighter
- elvitegr-cobicist-emtric-tenof
- etravirine
- Fatigue Relief Complex
- Intelence
- isoniazid-rifamp-pyrazinamide
- Priftin
- Reyataz
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- St. John's wort
- Stribild
- vit C-St. John wort-elder-hb30
- Women's Complex
Contraindicated
- Altavera (28)
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- Apri
- Aranelle (28)
- Aubra
- Aviane
- Azurette (28)
- Balziva (28)
- Beyaz
- Brevicon (28)
- Briellyn
- Camila
- Camrese
- Camrese Lo
- Caziant (28)
- Chateal
- Crixivan
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- Depo-provera
- Depo-subq Provera 104
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- dolutegravir
- drospirenone-e.estradiol-lm.FA
- drospirenone-ethinyl estradiol
- Elinest
- Emoquette
- Enpresse
- Enskyce
- Errin
- Estarylla
- estradiol valerate-dienogest
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- Falmina (28)
- Femcon Fe
- fosamprenavir
- Generess Fe
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- Heather
- indinavir
- Introvale
- Invirase
- itraconazole
- Jencycla
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kariva (28)
- Kelnor 1/35 (28)
- ketoconazole
- Kurvelo
- L norgest&E estradiol-E estrad
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lexiva
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- medroxyprogesterone
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Minastrin 24 Fe
- Mircette (28)
- Mirena
- Modicon (28)
- Mono-linyah
- Mononessa (28)
- My Way
- Myzilra
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- nelfinavir
- Nexplanon
- Next Choice One Dose
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Nuvaring
- Ocella
- Ogestrel (28)
- Olysio
- Onmel
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- Philith
- Pimtrea (28)
- Pirmella
- Plan B One-step
- Portia
- Previfem
- Quartette
- Quasense
- Reclipsen (28)
- Safyral
- saquinavir mesylate
- Seasonique
- simeprevir
- Skyla
- Sporanox
- Sporanox Pulsepak
- Sprintec (28)
- Sronyx
- Syeda
- Tilia Fe
- Tivicay
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- Trinessa (28)
- Trivora (28)
- Velivet Triphasic Regimen (28)
- Vestura (28)
- Viorele (28)
- Viracept
- Vyfemla (28)
- Wera (28)
- Wymzya Fe
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- amoxicil-clarithromy-lansopraz
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- Cancidas
- caspofungin
- clarithromycin
- Diskets
- Dolophine
- Kaletra
- lopinavir-ritonavir
- methadone
- Methadone Intensol
- Methadose
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Prevpac
- Disease of liver
- Drug-induced hepatitis
- Hepatic failure
- Lactating mother
- Prevention of HIV infection after exposure
- Severe hepatic disease
Contraindicated
- Abnormal hepatic function tests
- Acute renal failure
- Chronic hepatitis B
- Chronic hepatitis C
- Rhabdomyolysis
- Viral hepatitis C
Severe
Moderate
- None
VIRAMUNE (NEVIRAPINE)
- HIV infection
- None
- Nausea
- Skin rash
More Frequent
Severe
Less Severe
- Aphthous stomatitis
- Fever
- Hepatitis
- Stevens-johnson syndrome
- Acute abdominal pain
- Diarrhea
- Fatigue
- Headache disorder
- Lipodystrophy associated with HIV
- Myalgias
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute hepatic failure
- Anaphylaxis
- Anemia
- Angioedema
- Bullous dermatitis
- Cholestatic hepatitis
- Conjunctivitis
- DRESS syndrome
- Eosinophilia
- Granulocytopenic disorder
- Graves' disease
- Guillain-barre syndrome
- Hepatic necrosis
- Hepatomegaly
- Hypersensitivity drug reaction
- Hypophosphatemia
- Jaundice
- Kidney disease with reduction in GFR
- Lymphadenopathy
- Polymyositis
- Rhabdomyolysis
- Toxic epidermal necrolysis
- Urticaria
Less Severe
- Arthralgias
- Drowsy
- Facial edema
- Paresthesia
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Nevirapine (Immediate Release)
Higher incidence of granulocytopenia in combination with zidovudine. Increased risk of rash.
- 1 Day – 13 Years
- Higher incidence of granulocytopenia in combination with zidovudine. Increased risk of rash.
Nevirapine
- Severity Level:
2
- Additional Notes: Reports of fatal hepatotoxicity after treatment with chronic combination therapy
Contraindicated
Nevirapine
Cdc does not recommend breastfeeding in hiv-positive women
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Excreted | Not known; no or inclusive data | Cdc does not recommend breastfeeding in hiv-positive women |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Rarely, nevirapine has caused severe (sometimes fatal) liver problems. Seek immediate medical attention if you develop symptoms of liver problems such as persistent nausea, loss of appetite, vomiting, stomach/abdominal pain, dark urine, pale stools, yellowing eyes/skin, unusual tiredness, rash. Rarely, nevirapine has also caused serious (sometimes fatal) skin/allergic reactions.<br /><br />Get medical help right away if you have any signs of skin/allergic reactions, including rash, itching/swelling/redness (especially of the eyes/face), blisters, fever, persistent sore throat, unusual tiredness, mouth sores, severe dizziness, trouble breathing, signs of kidney problems (such as change in the amount of urine), muscle pain/tenderness/weakness, joint pain. Women are at increased risk for developing these severe reactions. To help decrease the risk of skin/allergic reactions in all patients, nevirapine is started at a lower dose for the first 14 days.<br /><br />Also, people with higher T-cell counts at the start of nevirapine treatment are at greater risk for liver problems. Therefore, nevirapine is usually only started if the T-cell count is fewer than 250 in women or fewer than 400 in men. Keep all medical and laboratory appointments so your doctor can monitor how you are responding to nevirapine.<br /><br />The risk of these serious side effects is high in the first 18 weeks and highest during the first 6 weeks of nevirapine treatment. However, these side effects may occur at any time while taking this medication. If you have stopped taking nevirapine because of liver problems or skin/allergic reactions, you must never take any form of nevirapine again. Tell all of your doctors and pharmacists if you have ever stopped taking nevirapine because of these types of reactions.
| HIV infection | |
| B20 | Human immunodeficiency virus [HIv] disease |
| B97.35 | Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
| 0-9 | A-Z |
|---|---|
| B20 | Human immunodeficiency virus [HIv] disease |
| B97.35 | Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
Formulary Reference Tool