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AGGRENOX (ASPIRIN/DIPYRIDAMOLE)
- Prevention of cerebral thrombosis
- Aspirin-dipyridamole Er Capsule,ext.release 12 Hr Multiphas
- Aggrenox Capsule, Extended Release
- By Indication
aspirin 25 mg-dipyridamole 200 mg capsule,ext.release 12 hr multiphase
- 1 capsule by oral route 2 times per day in the morning and evening
25 mg-200 mg capsule, extended release
- 1 capsule by oral route 2 times per day in the morning and evening
Prevention of cerebral thrombosis
- 1 capsule by oral route 2 times per day in the morning and evening
- Adempas
- Mifeprex
- mifepristone
- riociguat
Contraindicated
- Adenocard
- Adenoscan
- adenosine
- adenosine (diagnostic)
- Agrylin
- anagrelide
- apixaban
- Eliquis
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- Lexiscan
- regadenoson
- rivaroxaban
- varicella virus vacc live (PF)
- Varivax (pf)
- Xarelto
Severe
Moderate
- A-hydrocort
- A-methapred
- abciximab
- Activase
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- alteplase
- Anaprox
- Anaprox Ds
- Ansaid
- Anucort-hc
- Anusol-hc
- Aristospan Intra-articular
- Aristospan Intralesional
- Arixtra
- Arthrotec 50
- betamethasone acet & sod phos
- Brintellix
- Brisdelle
- budesonide
- Caldolor
- Cambia
- Cataflam
- Celestone Soluspan
- Celexa
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- citalopram
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Colocort
- Cortef
- Cortenema
- Cortifoam
- cortisone
- Coumadin
- Cymbalta
- dalteparin (porcine)
- Daypro
- Depacon
- Depakene
- Depakote
- Depakote Er
- Depakote Sprinkles
- Depo-medrol
- desvenlafaxine
- desvenlafaxine fumarate
- desvenlafaxine succinate
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- diclofenac epolamine
- diclofenac potassium
- diclofenac sodium
- diclofenac submicronized
- diclofenac-misoprostol
- divalproex
- Duexis
- duloxetine
- Ec-naprosyn
- Effexor Xr
- Elmiron
- enoxaparin
- Entocort Ec
- eptifibatide
- escitalopram oxalate
- etodolac
- Ez Use Joint-tunnel-trigger
- Feldene
- fenoprofen
- Fetzima
- First-duke's
- First-mary's Mouthwash
- Flanax
- Flector
- Flo-pred
- fludrocortisone
- fluoxetine
- flurbiprofen
- fluvoxamine
- fondaparinux
- Fragmin
- Grx Hicort 25
- Hemril-30
- heparin (porcine)
- heparin (porcine) in D5W
- heparin(porcine) in 0.45% NaCl
- heparin, porcine (PF)
- hydrocodone-ibuprofen
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- Integrilin
- Jantoven
- Kenalog
- ketoprofen
- ketorolac
- Khedezla
- lepirudin
- levomilnacipran
- Lexapro
- Lovenox
- Luvox Cr
- Medi-profen
- Mediproxen
- Medrol
- Medrol (pak)
- mefenamic acid
- meloxicam
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- Midol (naproxen)
- Millipred
- Millipred Dp
- milnacipran
- Mobic
- Motrin Ib
- Motrin Pm
- nabumetone
- Nalfon
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- Neoprofen (ibuprofen Lysn)(pf)
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- olanzapine-fluoxetine
- Orapred
- Orapred Odt
- oxaprozin
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- Pediapred
- Pennsaid
- pentosan polysulfate sodium
- Pexeva
- Physicians Ez Use M-pred
- piroxicam
- Ponstel
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- Pristiq
- Proctocort
- Provil
- Prozac
- Prozac Weekly
- pseudoephedrine-ibuprofen
- Rayos
- Rectacort-hc
- Refludan
- Reopro
- Reprexain
- Retavase
- reteplase
- Sarafem
- Savella
- sertraline
- Sinus & Cold-d
- Solaraze
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Sprix
- Stavzor
- sulindac
- Symbyax
- tenecteplase
- ticlopidine
- Tnkase
- tolmetin
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- Uceris
- valproate sodium
- valproic acid
- valproic acid (as sodium salt)
- venlafaxine
- Veripred 20
- Vicoprofen
- Viibryd
- vilazodone
- Vimovo
- Voltaren-xr
- vortioxetine
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- warfarin
- Zipsor
- Zoloft
- Zorvolex
- Aspirin exacerbated respiratory disease
- Gastrointestinal hemorrhage
- Hemolytic anemia from PK and g6PD deficiencies
- Hemophilia
- Peptic ulcer
- Reye's syndrome
- Von willebrand's disease
Contraindicated
- Alcoholism
- Erosive gastritis
- Gastrointestinal ulcer
- Gout
- Hypoprothrombinemia
- Systemic mastocytosis
- Thrombocytopenic disorder
- Thrombotic thrombocytopenic purpura
Severe
Moderate
- Anemia
- Disease of liver
- Hypotension
- Kidney disease with reduction in GFR
- Nasal polyp
- Unstable angina pectoris
- Vitamin K deficiency
AGGRENOX (ASPIRIN/DIPYRIDAMOLE)
- Prevention of cerebral thrombosis
- None
- Abdominal pain with cramps
- Diarrhea
- Dizziness
- Gastric acid hypersecretory conditions
- Gastrointestinal irritation
- Heartburn
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Pruritus of skin
- Skin rash
- Urticaria
- Flushing
- Headache disorder
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Allergic dermatitis
- Anaphylaxis
- Anemia
- Angina
- Angioedema
- Biliary calculus
- Blistering skin
- Bronchospastic pulmonary disease
- Cardiac arrhythmia
- Drug-induced hepatitis
- Dyspnea
- Gastrointestinal hemorrhage
- Gastrointestinal perforation
- Gastrointestinal ulcer
- Hemolytic anemia
- Hemorrhage
- Hepatitis
- Hypotension
- Hypothermia
- Interstitial nephritis
- Intracerebral hemorrhage
- Intracranial bleeding
- Jaundice
- Laryngeal edema
- Leukopenia
- Platelet aggregation inhibition
- Purpura
- Rectal bleeding
- Seizure disorder
- Tachycardia
- Thrombocytopenic disorder
- Urticaria
- Wheezing
Less Severe
- Abnormal hepatic function tests
- Acute confusion
- Agitation
- Alopecia
- Anorexia
- Arthritis
- Black tarry stools
- Drowsy
- Dyspepsia
- Epistaxis
- Erythema
- Fatigue
- Gastritis
- Gingival bleeding
- Hematoma
- Malaise
- Myalgias
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin rash
- Syncope
- Tinnitus
Contraindicated
None
Severe Precaution
Aspirin
Reye syndrome risk with viral illness, fever, and/or flu symptoms.
- 1 Day – 16 Years
- Reye syndrome risk with viral illness, fever, and/or flu symptoms.
Management or Monitoring Precaution
None
Aspirin (low Dose 25-150Mg)
- Severity Level:
2
- Additional Notes: Premature closure of ductus arteriosus; mat benefit vs. fetal risks
Dipyridamole
- Severity Level:
B
- Additional Notes:
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Aspirin (low Dose 25-150Mg)
Monitor nursing infant for antiplatelet effects
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Not known; no or inclusive data | Monitor nursing infant for antiplatelet effects |
No Known Risk
Dipyridamole
Small quantity excreted, no reports of adverse effects in infants.
General | Excretion Potential | Effect on Infant | Notes |
No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Small quantity excreted, no reports of adverse effects in infants. |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
Prevention of cerebral thrombosis | |
I65 | Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction |
I65.0 | Occlusion and stenosis of vertebral artery |
I65.01 | Occlusion and stenosis of right vertebral artery |
I65.02 | Occlusion and stenosis of left vertebral artery |
I65.03 | Occlusion and stenosis of bilateral vertebral arteries |
I65.09 | Occlusion and stenosis of unspecified vertebral artery |
I65.1 | Occlusion and stenosis of basilar artery |
I65.2 | Occlusion and stenosis of carotid artery |
I65.21 | Occlusion and stenosis of right carotid artery |
I65.22 | Occlusion and stenosis of left carotid artery |
I65.23 | Occlusion and stenosis of bilateral carotid arteries |
I65.29 | Occlusion and stenosis of unspecified carotid artery |
I65.8 | Occlusion and stenosis of other precerebral arteries |
I65.9 | Occlusion and stenosis of unspecified precerebral artery |
I66 | Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction |
I66.0 | Occlusion and stenosis of middle cerebral artery |
I66.01 | Occlusion and stenosis of right middle cerebral artery |
I66.02 | Occlusion and stenosis of left middle cerebral artery |
I66.03 | Occlusion and stenosis of bilateral middle cerebral arteries |
I66.09 | Occlusion and stenosis of unspecified middle cerebral artery |
I66.1 | Occlusion and stenosis of anterior cerebral artery |
I66.11 | Occlusion and stenosis of right anterior cerebral artery |
I66.12 | Occlusion and stenosis of left anterior cerebral artery |
I66.13 | Occlusion and stenosis of bilateral anterior cerebral arteries |
I66.19 | Occlusion and stenosis of unspecified anterior cerebral artery |
I66.2 | Occlusion and stenosis of posterior cerebral artery |
I66.21 | Occlusion and stenosis of right posterior cerebral artery |
I66.22 | Occlusion and stenosis of left posterior cerebral artery |
I66.23 | Occlusion and stenosis of bilateral posterior cerebral arteries |
I66.29 | Occlusion and stenosis of unspecified posterior cerebral artery |
I66.3 | Occlusion and stenosis of cerebellar arteries |
I66.8 | Occlusion and stenosis of other cerebral arteries |
I66.9 | Occlusion and stenosis of unspecified cerebral artery |
I67.2 | Cerebral atherosclerosis |
Z86.73 | Personal history of transient ischemic attack (TIa), and cerebral infarction without residual deficits |
0-9 | A-Z |
---|---|
I65 | Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction |
I65.0 | Occlusion and stenosis of vertebral artery |
I65.01 | Occlusion and stenosis of right vertebral artery |
I65.02 | Occlusion and stenosis of left vertebral artery |
I65.03 | Occlusion and stenosis of bilateral vertebral arteries |
I65.09 | Occlusion and stenosis of unspecified vertebral artery |
I65.1 | Occlusion and stenosis of basilar artery |
I65.2 | Occlusion and stenosis of carotid artery |
I65.21 | Occlusion and stenosis of right carotid artery |
I65.22 | Occlusion and stenosis of left carotid artery |
I65.23 | Occlusion and stenosis of bilateral carotid arteries |
I65.29 | Occlusion and stenosis of unspecified carotid artery |
I65.8 | Occlusion and stenosis of other precerebral arteries |
I65.9 | Occlusion and stenosis of unspecified precerebral artery |
I66 | Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction |
I66.0 | Occlusion and stenosis of middle cerebral artery |
I66.01 | Occlusion and stenosis of right middle cerebral artery |
I66.02 | Occlusion and stenosis of left middle cerebral artery |
I66.03 | Occlusion and stenosis of bilateral middle cerebral arteries |
I66.09 | Occlusion and stenosis of unspecified middle cerebral artery |
I66.1 | Occlusion and stenosis of anterior cerebral artery |
I66.11 | Occlusion and stenosis of right anterior cerebral artery |
I66.12 | Occlusion and stenosis of left anterior cerebral artery |
I66.13 | Occlusion and stenosis of bilateral anterior cerebral arteries |
I66.19 | Occlusion and stenosis of unspecified anterior cerebral artery |
I66.2 | Occlusion and stenosis of posterior cerebral artery |
I66.21 | Occlusion and stenosis of right posterior cerebral artery |
I66.22 | Occlusion and stenosis of left posterior cerebral artery |
I66.23 | Occlusion and stenosis of bilateral posterior cerebral arteries |
I66.29 | Occlusion and stenosis of unspecified posterior cerebral artery |
I66.3 | Occlusion and stenosis of cerebellar arteries |
I66.8 | Occlusion and stenosis of other cerebral arteries |
I66.9 | Occlusion and stenosis of unspecified cerebral artery |
I67.2 | Cerebral atherosclerosis |
Z86.73 | Personal history of transient ischemic attack (TIa), and cerebral infarction without residual deficits |
Formulary Reference Tool