MIDOL (ACETAMINOPHEN/PYRILAMINE MALEATE/CAFFEINE)

Contraindicated



• dipyridamole

Severe



• Acid Reducer (cimetidine)
• Acid Relief (cimetidine)
• Adenocard
• Adenoscan
• adenosine
• adenosine (diagnostic)
• cimetidine
• Curad Enema
• Disposable Enema
• Enema
• Enema Disposable
• Fleet Enema
• Fleet Enema Extra
• Fleet Pediatric
• Heartburn Relief
• Lexiscan
• Oral Saline Laxative
• Osmoprep
• Phosphate Laxative
• Preparation Cleansing
• Ready-to-use Enema
• Reclast
• regadenoson
• sod phos mono-sod phos dibasic
• sodium phosphates
• Tagamet Hb
• zoledronic acid
• zoledronic acid-mannitol-water
• Zometa

Contraindicated



• 30 day risk period post-myocardial infarction
• Acetaminophen overdose
• Acute hepatic failure
• Acute hepatitis C

Severe



• Angle-closure glaucoma
• Benign prostatic hyperplasia
• Bladder outflow obstruction
• Chronic idiopathic constipation
• Disease of liver
• Necrotizing enterocolitis
• Peptic ulcer
• Protein-calorie malnutrition
• Severe renal impairment
• Shock
• Stenosing peptic ulcer
• Urinary retention

Contraindicated

Pyrilamine

Possible CNS excitation and seizure risk in newborns.

Do not use in pediatrics <6 years of age unless clinician consultation.

• 1 Day – 29 Days
• 1 Possible CNS excitation and seizure risk in newborns.
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 30 Days – 6 Years
• 1 Possible CNS excitation and seizure risk in newborns.
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.

Severe Precaution

None

Management or Monitoring Precaution

Acetaminophen (oral,rectal)

Use weight based dosing in children less than 12 years.

Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.

Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.

Consult clinician prior to use. Limited safety data,

• 1 Day – 12 Years
• Use weight based dosing in children less than 12 years.
• 1 Day – 364 Days
• Use weight based dosing in children less than 12 years.
• 1 Years – 13 Years
• Use weight based dosing in children less than 12 years.
• 1 Day – 18 Years
• Use weight based dosing in children less than 12 years.

Caffeine

Use weight based dosing in children less than 12 years.

Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.

Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.

Consult clinician prior to use. Limited safety data,

• 1 Day – 12 Years
• Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
• Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
• 1 Day – 364 Days
• Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
• Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
• 1 Years – 13 Years
• Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
• Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.
• 1 Day – 18 Years
• Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.
• Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.

Pamabrom

Use weight based dosing in children less than 12 years.

Caution in: seizure disorder, cardiovascular disease, or in premature neonates with renal or hepatic impairment.

Adverse CNS effects of insomnia, restlessness, nervousness, and mild delirium, more severe in children.

Consult clinician prior to use. Limited safety data,

• 1 Day – 12 Years
• Consult clinician prior to use. Limited safety data,
• 1 Day – 364 Days
• Consult clinician prior to use. Limited safety data,
• 1 Years – 13 Years
• Consult clinician prior to use. Limited safety data,
• 1 Day – 18 Years
• Consult clinician prior to use. Limited safety data,